(n.) The act of predisposing, or the state of being predisposed; previous inclination, tendency, or propensity; predilection; -- applied to the mind; as, a predisposition to anger.
(n.) Previous fitness or adaptation to any change, impression, or purpose; susceptibility; -- applied to material things; as, the predisposition of the body to disease.
Example Sentences:
(1) Pedigree studies have suggested that there may be an inherited predisposition to many apparently nonfamilial colorectal cancers and a genetic model of tumorigenesis in common colorectal cancer has been proposed that includes the activation of dominantly acting oncogenes and the inactivation of growth suppressor genes.
(2) Thus, a4 and a2 alleles of the c-Ha-ras-1 may perhaps be viewed as genetic markers of predisposition to lung, ovarian and thyroid cancer, respectively, in combination with other clinical parameters.
(3) The reported findings strongly support the predisposition hypothesis.
(4) The characteristic predisposition to neoplasia exists, however, as probably does that to diabetes mellitus.
(5) Our knowledge of the pathogenesis of ordinary baldness is far from complete but a genetic predisposition is necessary and androgen production must be present.
(6) Predisposition to pancreatitis relates to duct size rather than stone size per se.
(7) Of CD patients, 92% (50% DR3 and 42% DR5,7) compared to 18% of the controls carry both DQA1*0501 and DQB1*0201 alleles, so that the combination confers an RR of 52, higher than both the risks of the single alleles (DQA1*0501 RR = 19, DQB1*0201 RR = 30), confirming the primary role of the dimer in determining genetic predisposition to CD both in DR3 and in DR5,7 subjects.
(8) For over two decades, evidence has been accumulating that supports a genetic predisposition to alcoholism and the presence of subgroups among alcoholics.
(9) A thromboembolism is sometimes predictable in individuals if there is migraine, visual disturbance, or certain predispositions seen in pregnancy such as toxemia or hypertension.
(10) Questionnaires assessing symptoms, disability and handicap, predisposition to anxiety, and current anxiety and depression were completed by 127 people attending neuro-otology clinics with a major complaint of vertigo or dysequilibrium.
(11) The functional interaction between prostacyclin and thromboxane was examined in terms of a number of risk factors for coronary heart disease (CHD), such as ageing, atherosclerosis, arterial hypertension, diabetes mellitus, obesity, hypokinesia, smoking, alcoholism, sex differences, and predisposition to the disease.
(12) Because the predisposition locus for multiple endocrine neoplasia type 2A (MEN2A) has been mapped to chromosome 10 by genetic linkage analysis, it has become possible to identify gene carriers by following the transmission of linked genetic markers from affected parents to offspring at risk for MEN2A.
(13) The findings suggest that migraine, major depression and anxiety disorders might share common predispositions.
(14) Microstructural rearrangements and nonhomologous recombination in nondisjunction of chromosomes during cell division are considered parallel with mosaicism as one of possible reasons of genetic predisposition.
(15) There was no correlation between specific HLA antigens and predisposition to develop cytomegalovirus infection.
(16) The certainty of a strong genetic predisposition to malignant melanoma was first established over 35 years ago.
(17) The sampling was balanced with respect to age, gender, and predisposition across the three ordinal exposure categories.
(18) Trait anxiety levels (predisposition to anxiety) and personality profiles were recorded in four novice anaesthetists prior to the start of their training in anaesthesia.
(19) Genetic predisposition to diabetes is characterized by immunodeficiency as evident from inadequate levels of antibodies to infectious or noninfectious antigens and absolute and relative deficiency in spleen lymphocyte subsets and total numbers of spleen cells.
(20) Tumor suppressor genes have been identified by genetic analysis either as loci associated with an inherited predisposition to certain tumors or by mapping studies that demonstrate allelic loss (reduction to homozygosity or loss of heterozygosity) during tumor development.
(1) This suggests that isolation increases sexual proclivity.
(2) Although one person may seem more sensitive than another, the difference may lie in a greater proclivity to complain.
(3) Infants' proclivity to imitate was used to investigate early memory.
(4) In general, proclivity and arousal had different effects on behavior.
(5) The proclivity for complications to evolve varies with age, brain areas involved, whether the event is hemorrhagic or nonhemorrhagic in nature, and the presence of concomitant systemic disease.
(6) As a result, the data suggest that such cells express an increased proclivity to undergo metaplastic change and complete neoplastic transformation.
(7) At the time the tabloids were nearly herniating themselves in order to expose lesser celebrities' chemical proclivities – the Sun went to the bother of flying Tulisa Contostavlos to both Las Vegas and then LA as part of a sting operation that eventually extracted the information that she knew someone who could get hold of some coke – but the matter quietly blew over.
(8) Through the flexibility of the membrane prism is a definite advantage, because of its proclivity to reduce visual acuity and increase aberrations its prescription for adults often must be limited to only one eye.
(9) Inasmuch as the colons of these patients have a clear proclivity to neoplastic transformation and recurrence, subtotal colectomy as the initial curative colon procedure is practiced.
(10) Later, he developed the Substance Abuse Proclivity Scale (SAP; MacAndrew, 1986), specifically for screening younger males, using adolescent and young adult substance misusing and nonmisusing males 16 to 22 years of age.
(11) This study investigated cross-modal transfer in infants by their proclivity to respond differentially to novel and familiar stimuli after familiarization in a different sensory modality.
(12) Choroid plexus neoplasm may be a manifestation of the inherited proclivity to tumor development in the breast cancer-sarcoma syndrome.
(13) It does not appear to be associated with a particular proclivity to evolve into carcinoma and short-term follow-up suggests that excisional biopsy is probably adequate therapy.
(14) They maintain that "one has within oneself proclivity toward growth and unity of personality ... and an automatic thrust toward expression" of these qualities (Yalom, 1980, p. 9).
(15) Meanwhile Igor Mladenovic writes: "Based on what you've seen so far in the tournament, would you say Becker has started implementing any visible modifications to Djokovic's game, especially with regards to his proclivity to finish points at the net?
(16) Entitlement and narcissistic proclivities are viewed according to the developmental history as well as the clinical manifestations (intensity, frequency, duration, and spread).
(17) These points are illustrated by discussions of how the structures of headgroup- and backbone-modified phospholipid analogues influence their proclivities to form distinct types of hydrated solid phases, dehydrated "crystralline" phases and nonlamellar phases.
(18) We conclude that MIP-101 has a high tumorigenic and invasive potential but a low metastatic proclivity, except when grown in the peritoneum, and that pretreatment of tumor-bearing animals with CEA affects the metastatic proclivity.
(19) He was stripped of his paternal dignity as details of his sexual proclivities were extracted.
(20) But the apparent disconnect between the film's subject and the technological proclivities of its key crew provoked some comment following the film's cinematic release.