(a.) First; chief; principal; as, the premier place; premier minister.
(a.) Most ancient; -- said of the peer bearing the oldest title of his degree.
(n.) The first minister of state; the prime minister.
Example Sentences:
(1) In order for the club to grow and sustain its ability to be a competitive force in the Premier League, the board has made a number of decisions which will strengthen the club, support the executive team, manager and his staff and enhance shareholder return.
(2) Mary's grief, which lasts for about the first half of the two-hour premiere special, is the finest work of the series so far by Michelle Dockery.
(3) There was also acknowledgement for two long-term servants to the men’s game who will both leave the Premier League for Major League Soccer this summer.
(4) The company also confirmed on Thursday as it launched its sports pay-TV offering at its new broadcasting base in the Olympic Park in Stratford, east London, that former BBC presenter Jake Humphrey will anchor its Premier League coverage.
(5) Huth, a Stoke player for more than five years, has made only one Premier League appearance since suffering a knee injury in November 2013.
(6) I would like to see much more of that money go down to the grassroots.” The Premier League argues that its focus must remain on investing in the best players and facilities and claims it invests more in so-called “good causes” than any other football league.
(7) The mayor of London had said in a Twitter exchange in July that it was a “ludicrous urban myth” that Britain’s premier shopping street was one of the world’s most polluted thoroughfares, saying that the capital’s air quality was “better than Paris and other European cities”.
(8) John Carver witnessed signs of much-needed improvement from the visitors in a purposeful spell either side of the interval but it was not enough to prevent a fifth successive Premier League defeat.
(9) The joint Premier League leaders announced the 21-year-old, who can play in central midfield or at right-back, had signed a contract until 2020.
(10) FC Terek Grozny, the newly energised team based in the troubled Caucasus republic of Chechnya , is hoping a slew of high-profile international acquisitions will help it make waves in the Russian premier league, which kicked off last weekend.
(11) Absolute has raised its profile with big-name signings such as Frank Skinner and bought live Premier League football rights for the first time for this season .
(12) With Everton heading for a sixth-placed finish in the Premier League, the additional television revenue and prospect of further funds from Fellaini, the club are confident of appointing an "equally significant" successor to Moyes, according to the chairman, Bill Kenwright.
(13) It is trying to position Sky Arts as the country's premier cultural channel as it attempts to demonstrate to politicians and regulators that it can produce programming that was once the preserve of public service broadcasters like the BBC.
(14) United do not need permission from the Premier League or any other governing body to arrange the games, so the decision will be taken on a logistical basis.
(15) The Liverpool manager was incensed by Lee Mason's performance at the Etihad Stadium on Boxing Day, when a 2-1 defeat cost his team the Premier League leadership and Raheem Sterling had a first half goal disallowed for an incorrect offside call.
(16) Newcastle United are “devastated” by their relegation from the Premier League, according to the club’s managing director Lee Charnley.
(17) Following a run which included eight straight draws in the Premier League and a 3-0 defeat at Tottenham last Wednesday, Mubarak had reached the conclusion that Hughes and his coaching staff were not realising the potential of the players City had assembled.
(18) They watch the Premier League everywhere in Africa."
(19) It’s a huge crisis,” added Allan, who is a director of Premier Oil in addition to chairing Brindex.
(20) Watford confirm signing of Uruguay defender Miguel Britos from Napoli Read more Gestede, 26, saw a move to the Premier League fall through in January after Blackburn turned down an offer from Crystal Palace.
Primer
Definition:
(n.) One who, or that which, primes
(n.) an instrument or device for priming; esp., a cap, tube, or water containing percussion powder or other compound for igniting a charge of gunpowder.
(a.) First; original; primary.
(n.) Originally, a small prayer book for church service, containing the little office of the Virgin Mary; also, a work of elementary religious instruction.
(n.) A small elementary book for teaching children to read; a reading or spelling book for a beginner.
(n.) A kind of type, of which there are two species; one, called long primer, intermediate in size between bourgeois and small pica [see Long primer]; the other, called great primer, larger than pica.
Example Sentences:
(1) The following conclusions emerge: (i) when the 3' or the 3' penultimate base of the oligonucleotide mismatched an allele, no amplification product could be detected; (ii) when the mismatches were 3 and 4 bases from the 3' end of the primer, differential amplification was still observed, but only at certain concentrations of magnesium chloride; (iii) the mismatched allele can be detected in the presence of a 40-fold excess of the matched allele; (iv) primers as short as 13 nucleotides were effective; and (v) the specificity of the amplification could be overwhelmed by greatly increasing the concentration of target DNA.
(2) Elongation of existing RNA primers by the human polymerase-primase was semi-processive; following primer binding the DNA polymerase continuously incorporated 20 to 50 nucleotides, then it dissociated from the template DNA.
(3) This cDNA was obtained because of an identical 10 bp match with the 3' end of one of the GnRH primers.
(4) When PCR products in each of the 12 cats were subjected to a second amplification using the same primer pair (two-step amplification: double PCR), FIV proviral DNA was detected in all of the cats.
(5) In junctions, 3' PSS termini are preserved by fill-in DNA synthesis, although their 5' recessed ends cannot serve as a primer.
(6) Previous studies demonstrated that, when poly(dT).oligo(dA) was used as a template-primer, both proteins were required for poly(dA) synthesis.
(7) 5'-Ends of transcripts of the region were located by S1 nuclease mapping and primer extension.
(8) Nucleotide incorporation kinetics were determined and sequence specific pausing was analyzed by primer-extension.
(9) Primer extension and S1 nuclease protection analysis demonstrate that the hepatic and kidney specific mRNAs are transcriptionally initiated at different sites within the sialyltransferase gene.
(10) alpha 1 and alpha 2 were very similar as DNA polymerases in their sensitivity to several inhibitors and their preference for template-primers, except that alpha 1 had a slightly greater preference for poly (dT) X (rA)10 than alpha 2 did.
(11) Our results indicate that provirus expression occurs by two different mechanisms: one provirus acquired a single base pair mutation in the retrovirus tRNA primer binding site, permitting provirus expression; expression of three proviruses was mediated by 5'-flanking DNA sequences.
(12) Cognate sites in genomes that diverged approximately 100 million years ago can be detected by PCR assays based on primer pairs from unique sequences.
(13) HDV cDNA was then directly amplified with Taq polymerase using three pairs of specific primers.
(14) This reaction involved the synthesis of a short oligoribonucleotide primer which was then extended into a DNA chain.
(15) cDNA was prepared by reverse transcription of peripheral blood mRNA and amplified by the polymerase chain reaction (PCR) using primers corresponding to sequences 400 bp apart on the cDNA, spanning the last three exons (X, Y, Z) of the beta-Sp gene.
(16) B.subtilis phage M2 uses a protein, instead of RNA, as the primer of its DNA replication.
(17) Optimum specific amplification resulted when the primer annealing temperature was 60 degrees C. The gene fragment was amplifiable in 25 different Brucella species and strains.
(18) Primer extension experiments show that in fission yeast transcripts are initiated at the same starting point as in tomato, indicating for the first time that a plant promoter can be correctly recognized in fission yeast.
(19) Genomic clones for the mouse estrogen receptor have been isolated from a cosmid library and used in conjunction with the cDNA clones to study the expression of the receptor in vivo by RNase mapping, primer extension, and Northern blotting.
(20) By using primer 1 (5'-AAAGAATTCATGGAATCCAGGATCTG-3', upstream nucleotides 157 to 2877), primer 2 (5'-AAAGAATTCATGAACGTGAAGGAATCG-3', upstream nucleotides 1846 to 2877), and primer 4(5'-ATAAAGCTTAATCAGACGTTCTCTTCTTC-3', downstream nucleotides 157 to 2877 and 1846 to 2877), the HCMV B gene code region sequence and its glycoprotein 52 kd antigenic domain sequence were amplified from the recombinant plasmid pBH1 DNA containing the HCMV B gene.