(a.) Highest in rank, authority, character, importance, or degree; most considerable or important; chief; main; as, the principal officers of a Government; the principal men of a state; the principal productions of a country; the principal arguments in a case.
(a.) Of or pertaining to a prince; princely.
(n.) A leader, chief, or head; one who takes the lead; one who acts independently, or who has controlling authority or influence; as, the principal of a faction, a school, a firm, etc.; -- distinguished from a subordinate, abettor, auxiliary, or assistant.
(n.) The chief actor in a crime, or an abettor who is present at it, -- as distinguished from an accessory.
(n.) A chief obligor, promisor, or debtor, -- as distinguished from a surety.
(n.) One who employs another to act for him, -- as distinguished from an agent.
(n.) A thing of chief or prime importance; something fundamental or especially conspicuous.
(n.) A capital sum of money, placed out at interest, due as a debt or used as a fund; -- so called in distinction from interest or profit.
(n.) The construction which gives shape and strength to a roof, -- generally a truss of timber or iron, but there are roofs with stone principals. Also, loosely, the most important member of a piece of framing.
(n.) In English organs the chief open metallic stop, an octave above the open diapason. On the manual it is four feet long, on the pedal eight feet. In Germany this term corresponds to the English open diapason.
(n.) A heirloom; a mortuary.
(n.) The first two long feathers of a hawk's wing.
(n.) One of turrets or pinnacles of waxwork and tapers with which the posts and center of a funeral hearse were formerly crowned.
(n.) A principal or essential point or rule; a principle.
Example Sentences:
(1) In addition to their involvement in thrombosis, activated platelets release growth factors, most notably a platelet-derived growth factor (PDGF) which may be the principal mediator of smooth muscle cell migration from the media into the intima and of smooth muscle cell proliferation in the intima as well as of vasoconstriction.
(2) While stereology is the principal technique, particularly in its application to the parenchyma, other compartments such as the airways and vasculature demand modifications or different methods altogether.
(3) Chromatography and immunoassays are the two principal techniques used in research and clinical laboratories for the measurement of drug concentrations in biological fluids.
(4) This paper reports, principally, the caries results of the first three surveys of 5, 12 and 5-year-olds undertaken at the end of 1987, 1988 and 1989, respectively.
(5) Rigidly fixing the pubic symphysis stiffened the model and resulted in principal stress patterns that did not reflect trabecular density or orientations as well as those of the deformable pubic symphysis model.
(6) The binding parameters indicate that the principal activating effect of UMP is not simply to increase the affinity of the enzyme for glucose.
(7) Mononuclear phagocytic cells from patients with either principal form of leprosy functioned similarly to normal monocytes in phagocytosis while their fungicidal activity for C. pseudotropicalis was statistically significantly altered and was more evident in the lepromatous than in the tuberculoid type.
(8) In the terminal segment of the hamster epididymidis there was some evidence of micro-merocrine protein secretion a the level of the principal cells and clear evidence of granular secretion in the light cells, presumable of glycoproteins.
(9) In the analysis of background fluorescence, the principal components were, as for the two-step technique, autofluorescence and propidium spectral overlap.
(10) However, at Period B, neutrophil numbers in the BAL fluid were increased in the principal but not in the control animals.
(11) Principal conclusions are: 1) rapid change to predominantly heterosexual HIV transmission can occur in North America, with serious societal impact; 2) gender-specific clinical features can lead to earlier diagnosis of HIV infection in women; 3) HIV infection in women does not pursue an inherently more rapid course than that observed in men.
(12) The concentrations of the principal extratesticular androgens and estradiol do not seem to have a quantitative influence on these androphilic proteins either.
(13) A principal function of GPIb is its attachment to von Willebrand Factor (vWF) on injured blood vessels which leads to the adhesion of platelets to these vessels.
(14) The principal variables influencing a particular configuration and their effects are indicated.
(15) The principal form of HMTs produced by these human peripheral blood monocytes has been subjected to biochemical, functional, and serological characterization.
(16) Micronutrient antioxidants such as alpha-tocopherol, the principal lipid-soluble antioxidant, assume potential significance because levels can be manipulated by dietary measures without resulting in side effects.
(17) Cytochrome oxidase histochemistry revealed patchy patterns of the enzyme activity in transverse sections through the caudal part of the ventral subnucleus of the principal sensory trigeminal nucleus, interpolar spinal trigeminal nucleus, and layer IV of the caudal spinal trigeminal nucleus in the cat.
(18) 3. an up-to-date review of the principal methods and systems used to measure the sedimentation rate--Automation of the Westergren initial methodology.
(19) • Queen Margaret Union, one of the University of Glasgow's two student unions, says 200 students there are marching on the principal's office at the moment to present an anti-cuts petition.
(20) This observation provides corroboration for the identification of the principal CCK-I neuron in the rat olfactory bulb as the centrally projecting middle tufted cell.
Proprietor
Definition:
(n.) One who has the legal right or exclusive title to anything, whether in possession or not; an owner; as, the proprietor of farm or of a mill.
Example Sentences:
(1) The Lib Dems and Labour, after frantic consultations, announced they would table alternative amendments to introduce an element of statute and ensure the new press regulatory body was free from industry interference – two issues that the majority of newspaper proprietors have stoutly opposed.
(2) Desmond, the straight-talking media proprietor whose empire including the Daily Star, Daily Express and OK!
(3) Shortly after her appearance she was appointed the main producer of Today on Radio 4, running coverage of major stories including the trial of former Daily Telegraph proprietor Conrad Black in Chicago.
(4) But that is hardly surprising given that the editor in chief of the Daily Mail this month condemned the fact that the multimillionaire proprietor "who'd made his money from porn" was deemed "a fit and proper person to own a newspaper" in a speech at the Leveson inquiry.
(5) Hotel and accommodation managers and proprietors 10.
(6) Hotel and accommodation managers and proprietors £32,470 7.795 10.
(7) Adel Abbas is the proprietor of the Top Coast coffee shop and restaurant in the Karrada district.
(8) You had a tumultuous tenure as editor of The Lady during which you got into trouble with the proprietors for carrying an interview with Tracey Emin in which she talked about sewing being a good distraction from masturbation.
(9) The ill-fated free paper war cost both proprietors millions, and with its circulation spiralling downwards ultimately led Lebedev to take the Standard free as well .
(10) The government’s hold over main-stream media proprietors has meant that disillusioned liberal commentators who may have supported Erdogan’s reform efforts in the past have found themselves out of a job.
(11) Journalists who work here are not part of the press pack who must always keep one eye looking over their shoulder at their proprietor’s political whims – on business, on taxation or the European Union.
(12) For the sake of clarity it is worth pointing out that "the rich" Lord Lester is referring to are the rich who complain of being defamed, not the rich newspaper proprietors.
(13) "The transaction can only affect a cross-media audience and there is no reduction in the number of independent newspaper proprietors or TV broadcasters in the UK as a result of the transaction.
(14) It is standard for newspaper proprietors, however, to offer a month or four weeks' salary for every year worked, although many place limits on any lump sum received.
(15) Yet the proprietors, Minnie, Sweet Dave and her other colleagues, are nowhere to be found.
(16) MacKenzie denied Diamond's claim that News International proprietor Rupert Murdoch had instructed his editors to target her after she confronted him at a social event.
(17) He remains available for the occasional newspaper interview with a friendly proprietor and, at conference time, finds time for a 20-minute breakfast inquisition.
(18) He said the hacking affairs and the Leveson and committee inquiries had proven that politicians, the media and media proprietors had become far too close.
(19) Dominic Mohan told the inquiry that the proprietor of what is arguably Britain's most influential paper at election time supported the decision but was not solely responsible for it.
(20) Former KGB officer Alexander Lebedev yesterday finally signed the deal to become proprietor of the London Evening Standard .