(a.) Highest in rank, authority, character, importance, or degree; most considerable or important; chief; main; as, the principal officers of a Government; the principal men of a state; the principal productions of a country; the principal arguments in a case.
(a.) Of or pertaining to a prince; princely.
(n.) A leader, chief, or head; one who takes the lead; one who acts independently, or who has controlling authority or influence; as, the principal of a faction, a school, a firm, etc.; -- distinguished from a subordinate, abettor, auxiliary, or assistant.
(n.) The chief actor in a crime, or an abettor who is present at it, -- as distinguished from an accessory.
(n.) A chief obligor, promisor, or debtor, -- as distinguished from a surety.
(n.) One who employs another to act for him, -- as distinguished from an agent.
(n.) A thing of chief or prime importance; something fundamental or especially conspicuous.
(n.) A capital sum of money, placed out at interest, due as a debt or used as a fund; -- so called in distinction from interest or profit.
(n.) The construction which gives shape and strength to a roof, -- generally a truss of timber or iron, but there are roofs with stone principals. Also, loosely, the most important member of a piece of framing.
(n.) In English organs the chief open metallic stop, an octave above the open diapason. On the manual it is four feet long, on the pedal eight feet. In Germany this term corresponds to the English open diapason.
(n.) A heirloom; a mortuary.
(n.) The first two long feathers of a hawk's wing.
(n.) One of turrets or pinnacles of waxwork and tapers with which the posts and center of a funeral hearse were formerly crowned.
(n.) A principal or essential point or rule; a principle.
Example Sentences:
(1) In addition to their involvement in thrombosis, activated platelets release growth factors, most notably a platelet-derived growth factor (PDGF) which may be the principal mediator of smooth muscle cell migration from the media into the intima and of smooth muscle cell proliferation in the intima as well as of vasoconstriction.
(2) While stereology is the principal technique, particularly in its application to the parenchyma, other compartments such as the airways and vasculature demand modifications or different methods altogether.
(3) Chromatography and immunoassays are the two principal techniques used in research and clinical laboratories for the measurement of drug concentrations in biological fluids.
(4) This paper reports, principally, the caries results of the first three surveys of 5, 12 and 5-year-olds undertaken at the end of 1987, 1988 and 1989, respectively.
(5) Rigidly fixing the pubic symphysis stiffened the model and resulted in principal stress patterns that did not reflect trabecular density or orientations as well as those of the deformable pubic symphysis model.
(6) The binding parameters indicate that the principal activating effect of UMP is not simply to increase the affinity of the enzyme for glucose.
(7) Mononuclear phagocytic cells from patients with either principal form of leprosy functioned similarly to normal monocytes in phagocytosis while their fungicidal activity for C. pseudotropicalis was statistically significantly altered and was more evident in the lepromatous than in the tuberculoid type.
(8) In the terminal segment of the hamster epididymidis there was some evidence of micro-merocrine protein secretion a the level of the principal cells and clear evidence of granular secretion in the light cells, presumable of glycoproteins.
(9) In the analysis of background fluorescence, the principal components were, as for the two-step technique, autofluorescence and propidium spectral overlap.
(10) However, at Period B, neutrophil numbers in the BAL fluid were increased in the principal but not in the control animals.
(11) Principal conclusions are: 1) rapid change to predominantly heterosexual HIV transmission can occur in North America, with serious societal impact; 2) gender-specific clinical features can lead to earlier diagnosis of HIV infection in women; 3) HIV infection in women does not pursue an inherently more rapid course than that observed in men.
(12) The concentrations of the principal extratesticular androgens and estradiol do not seem to have a quantitative influence on these androphilic proteins either.
(13) A principal function of GPIb is its attachment to von Willebrand Factor (vWF) on injured blood vessels which leads to the adhesion of platelets to these vessels.
(14) The principal variables influencing a particular configuration and their effects are indicated.
(15) The principal form of HMTs produced by these human peripheral blood monocytes has been subjected to biochemical, functional, and serological characterization.
(16) Micronutrient antioxidants such as alpha-tocopherol, the principal lipid-soluble antioxidant, assume potential significance because levels can be manipulated by dietary measures without resulting in side effects.
(17) Cytochrome oxidase histochemistry revealed patchy patterns of the enzyme activity in transverse sections through the caudal part of the ventral subnucleus of the principal sensory trigeminal nucleus, interpolar spinal trigeminal nucleus, and layer IV of the caudal spinal trigeminal nucleus in the cat.
(18) 3. an up-to-date review of the principal methods and systems used to measure the sedimentation rate--Automation of the Westergren initial methodology.
(19) • Queen Margaret Union, one of the University of Glasgow's two student unions, says 200 students there are marching on the principal's office at the moment to present an anti-cuts petition.
(20) This observation provides corroboration for the identification of the principal CCK-I neuron in the rat olfactory bulb as the centrally projecting middle tufted cell.
Ringleader
Definition:
(n.) The leader of a circle of dancers; hence, the leader of a number of persons acting together; the leader of a herd of animals.
(n.) Opprobriously, a leader of a body of men engaged in the violation of law or in an illegal enterprise, as rioters, mutineers, or the like.
Example Sentences:
(1) The government blamed the opposition, jailing alleged ringleader Vladimir Kozlov amid an international outcry, closing down his party and shutting dozens of independent media outlets.
(2) Albums include Viva Hate, Vauxhall And I, and Ringleader Of The Tormentors.
(3) French, who has joined the nightly marches, said police appeared to have caught agitator ringleaders the previous 24 hours.
(4) Prison staff are working with Nottinghamshire Police to identify the ringleaders.
(5) Muktar Said-Ibrahim, the suspected ringleader, was seen in Rome several weeks before the failed attack, two witnesses told the Guardian yesterday.
(6) A former journalist, Vladimir Anikeev, believed to be the ringleader of the group, is also among those arrested, according to reports.
(7) And the BBC reports that Spanish police targeted "ringleaders" behind the "Occupy Congress" movement.
(8) When soldiers eventually broke their siege and killed the ringleaders, Bin Laden was seething.
(9) They were arrested reportedly because they were believed to have been ringleaders in earlier protests over the weekend.
(10) French media stressed that it was a public tip-off that ultimately helped police locate Abdeslam, just as it had been for the ringleader, Abaaoud.
(11) Abdeslam hunt map Belgian investigators have placed Abdeslam – a childhood friend of the terror cell’s ringleader, Abdelhamid Abaaoud – in Budapest in early September, and later on the Austrian border, allegedly picking up two of the attackers who had joined the flow of refugees and migrants heading up through the Balkans.
(12) The court, however, accepted a petition from lawyers for the accused ringleader – Yosef Haim Ben David, 31 – to reconsider a claim of insanity.
(13) Along with Abdelhamid Abaaoud, the ringleader of the 13 November attacks in Paris, Kriket was convicted in absentia last July of recruiting Islamist fighters for Syria in Belgium .
(14) Reader’s fellow ringleaders, John “Kenny” Collins, 75, Daniel Jones, 61, and Terry Perkins, 67, were each jailed for seven years after pleading guilty to conspiracy to commit burglary last September.
(15) Australia’s immigration minister, Peter Dutton , has praised Papua New Guinean authorities for “professionally” moving to end the standoff at the Manus Island detention centre by taking away alleged ringleaders.
(16) The support networks are so deeply implanted into Serbia's most powerful institutions that some question whether Vukcevic will go after their ringleaders.
(17) One of the Hatton Garden heist ringleaders has had a stroke, is being tested for suspected cancer and may not have long to live, a court has heard.
(18) We also need to consider if Singh's death, as the alleged ringleader of the conspiracy, will hurt the chances of bringing the other five suspects to justice.
(19) The files, which contained information dating back to the 1980s, contained descriptions such as "militant ringleader", "agitator", "is a good worker but has proved to be very militant", "do not touch", and "that subject is a very bad troublemaker and would not be re-employed".
(20) The Revolutionary Guards have accused Zaghari-Ratcliffe of fomenting a “soft overthrow” of the Islamic Republic and being the ringleader of a network of “hostile institutions” associated with foreign intelligence agencies, allegations that her husband has said are untrue.