(v. t.) To examine, as a wound, an ulcer, or some cavity of the body, with a probe.
(v. t.) Fig.: to search to the bottom; to scrutinize or examine thoroughly.
(n.) An instrument for examining the depth or other circumstances of a wound, ulcer, or cavity, or the direction of a sinus, of for exploring for bullets, for stones in the bladder, etc.
(1) A series of human cDNA clones of various sizes and relative localizations to the mRNA molecule were isolated by using the human p53-H14 (2.35-kilobase) cDNA probe which we previously cloned.
(2) Theophylline kinetics, as an in vivo probe for the potentially toxic cytochrome P-450I pathway of drug metabolism, were studied in 11 healthy volunteers and 11 patients with calcific chronic pancreatitis at Madras, South India.
(3) Five probes of high specificity to individual chromosomes (chromosomes 3, 11, 17, 18 and X) were hybridized in situ to metaphase chromosomes of different individuals.
(4) In order to determine the extent of this similarity, I have developed a panel of probes for many of the Pacl restriction fragments and have shown that most of the Pacl and Notl fragments found in MBa are also present in MBb.
(5) The haplotype of the recombinant X chromosome of each of 241 backcross progeny has been established using the X-linked anchor loci Otc, Hprt, Dmd, Pgk-1, and Amg and the additional probes DXSmh43 and Cbx-rs1.
(6) Periodontal disease activity is defined clinically by progressive loss of probing attachment and radiographically by progressive loss of alveolar bone.
(7) The mean histamine level in the first 10-min sample following probe insertion was 39.4 nM.
(8) Five of them had a fast-moving Eco RI fragment 5.6 kb long that hybridized with zeta-specific probe but not with alpha-specific probe.
(9) We studied the haemodynamic (ultrasound Doppler flow probes) effects of synthetic atriopeptin II at natriuretic doses in conscious rats.
(10) DNA from 9% (47 of 529) of the E. coli colonies tested hybridized with the ST probe, whereas only 5% (28 of 529) produced ST as measured by the suckling mouse bioassay.
(11) Likewise, they had little or no effects on the fluorescence anisotropy of TMA-DPH, which is also thought to be located in the interfacial region of the lipid bilayer, either when the probe was located in the outer layer of the plasma membrane or when the probe was located in the inner membrane compartment.
(12) Sequence specific binding of protein extracts from 13 different yeast species to three oligonucleotide probes and two points mutants derived from Saccharomyces cerevisiae DNA binding proteins were tested using mobility shift assays.
(13) The probe has been used for the identification of new Legionella-like strains isolated from the environment.
(14) Therefore, we conclude this is a bovine DR beta-like pseudogene, BoDR beta I. Exon-containing regions have been used as probes in Southern blot analyses of bovine genomic DNA digested with EcoRI.
(15) The adherence of 51Cr-labeled platelets to rabbit aortae everted on probes rotated in platelet-red cell suspensions has been measured.
(16) A 2.7-kilobase DNA fragment carrying the entire exotoxin A (ETA) structural gene was divided into three nonoverlapping probes.
(17) The indication of the DNA probe method would be considered in the four cases as follows, 1. necessity of the special equipment to isolate the pathogen, 2. necessity of the long period to isolate the pathogen, 3. existence of the cross reaction among the pathogen and relative organisms in the immunological procedure, 4. existence of the difficulty to identify the species of the pathogen by the ordinary procedure.
(18) Slight cross-reactivity was apparent when crude preparations of cellular or culture filtrate antigens, used in this laboratory to detect antibodies to Candida albicans, Coccidioides immitis and Cryptococcus neoformans, were probed with hyperimmune rabbit antisera to A. fumigatus.
(19) The results, together with the known geometry of the enzyme, indicate that active site probes in the dodecamer are widely separated and that energy transfer occurs from a single donor to two or three acceptors on adjacent subunits.
(20) The availability of locus-specific probes should significantly expand the role of minisatellite markers in population biology.
(n.) Tried virtue or integrity; approved moral excellence; honesty; rectitude; uprightness.
(1) The alleged conduct was not conduct that could adversely affect the probity of the exercise of an official function by a public official.
(2) Members of the board of the Food Standards Agency (FSA) have been ordered to declare any contact they have with its former chief executivefor two years following Tim Smith's controversial move to Tesco to ensure "proper governance and probity".
(3) The Biological Stain Commission-sponsored workshop was convened to address the following issues: a manufacturers' testing program for probity of commercial antibodies, development of a manual for performance criteria and quality control assurance procedures, standardization of package inserts, standardization of information provided in the Materials and Methods sections of publications, establishment of a reagent and procedure clearing house, study of the effects of different fixation regimes on tissue antigens, and investigation of the environmental conditions needed for antigen-antibody interaction.
(4) Douglas has always advocated new politics, probity, transparency – this is his public image.
(5) We will establish partnerships between different countries’ institutions and professions to help build a shared culture of honesty and probity.
(6) In the circumstances, you do have to marvel at that mulishly self-regarding "for any offence caused" – the classic non-apology apology typically proffered by those with a belief in their own absolute probity, which is as unshakeable as it is misplaced.
(7) This British bank has generally enjoyed a high reputation for probity (as these places go) until yesterday, when some New York regulator apparently denounced Standard as a 'rogue institution.'
(8) She has had her problems with the Tories, in particular over Boris Johnson's attempted appointment of former London Evening Standard editor Veronica Wadley to the chair of Arts Council London (a letter of Forgan's to Bradshaw, questioning the probity of the recruitment process, was leaked last year; there have been Tory mutterings that Forgan is too bound up with the Labour establishment).
(9) Looking into the Eds’ eyes, wavering voters do not spy the cutting zeal that reassures them of fiscal probity; but nor do they offer a genuine alternative to those fed up of Osborne’s botch job.
(10) If a leader can convince voters they will not back-slide in this way, then – with probity, empathy and practical balms for a country gripped by a sustained squeeze on living standards – they might still cut through.
(11) And, while the emphasis has mostly been on the probity of Mann's hockey stick, most researchers I have spoken to regard the M&M study as far more deeply flawed.
(12) "He had a complete loss of confidence when he described Jeffrey Archer as a man of probity and integrity – only for us to watch him go to jail.
(13) • Focus on technical skills as well as probity of approved persons.
(14) One energy industry analyst said the prospect of a $1bn government loan for Adani’s railway showed a lack of financier interest and raised probity questions, given public money would go to a private entity controlled by the Adani family through offshore tax havens.
(15) Manipulating the system, or indeed any unscrupulous behaviour, would have been unthinkable, Zombanakis says, because the system was based not only on the probity of men in bowler hats and pinstripe suits but on something more important still: an unwritten code of conduct inspired entirely by fair play.
(16) But I and my family - my father and my two uncles, although they've all gone now - have had an enduring reputation for probity, integrity and honesty," he added.
(17) To spread best practice, ensure probity and the equitable use of public funds, and to ensure transparency and accountability locally, we need a devolved schools system.
(18) If the party did much more of what it says on the tin, the doubts about honesty, trust and appeal would dissolve as its reputation would be enhanced by probity and authenticity.
(19) Ensuring the probity of the foreign exchange rates is “incredibly important” for the FX market and “fundamentally important” for the credibility of the Bank of England itself , Carney added.
(20) Bailey said the initiative to seek written promises of probity from editorial executives did not extend to former staff such as Morgan.