(v. t.) To examine, as a wound, an ulcer, or some cavity of the body, with a probe.
(v. t.) Fig.: to search to the bottom; to scrutinize or examine thoroughly.
(n.) An instrument for examining the depth or other circumstances of a wound, ulcer, or cavity, or the direction of a sinus, of for exploring for bullets, for stones in the bladder, etc.
Example Sentences:
(1) A series of human cDNA clones of various sizes and relative localizations to the mRNA molecule were isolated by using the human p53-H14 (2.35-kilobase) cDNA probe which we previously cloned.
(2) Theophylline kinetics, as an in vivo probe for the potentially toxic cytochrome P-450I pathway of drug metabolism, were studied in 11 healthy volunteers and 11 patients with calcific chronic pancreatitis at Madras, South India.
(3) Five probes of high specificity to individual chromosomes (chromosomes 3, 11, 17, 18 and X) were hybridized in situ to metaphase chromosomes of different individuals.
(4) In order to determine the extent of this similarity, I have developed a panel of probes for many of the Pacl restriction fragments and have shown that most of the Pacl and Notl fragments found in MBa are also present in MBb.
(5) The haplotype of the recombinant X chromosome of each of 241 backcross progeny has been established using the X-linked anchor loci Otc, Hprt, Dmd, Pgk-1, and Amg and the additional probes DXSmh43 and Cbx-rs1.
(6) Periodontal disease activity is defined clinically by progressive loss of probing attachment and radiographically by progressive loss of alveolar bone.
(7) The mean histamine level in the first 10-min sample following probe insertion was 39.4 nM.
(8) Five of them had a fast-moving Eco RI fragment 5.6 kb long that hybridized with zeta-specific probe but not with alpha-specific probe.
(9) We studied the haemodynamic (ultrasound Doppler flow probes) effects of synthetic atriopeptin II at natriuretic doses in conscious rats.
(10) DNA from 9% (47 of 529) of the E. coli colonies tested hybridized with the ST probe, whereas only 5% (28 of 529) produced ST as measured by the suckling mouse bioassay.
(11) Likewise, they had little or no effects on the fluorescence anisotropy of TMA-DPH, which is also thought to be located in the interfacial region of the lipid bilayer, either when the probe was located in the outer layer of the plasma membrane or when the probe was located in the inner membrane compartment.
(12) Sequence specific binding of protein extracts from 13 different yeast species to three oligonucleotide probes and two points mutants derived from Saccharomyces cerevisiae DNA binding proteins were tested using mobility shift assays.
(13) The probe has been used for the identification of new Legionella-like strains isolated from the environment.
(14) Therefore, we conclude this is a bovine DR beta-like pseudogene, BoDR beta I. Exon-containing regions have been used as probes in Southern blot analyses of bovine genomic DNA digested with EcoRI.
(15) The adherence of 51Cr-labeled platelets to rabbit aortae everted on probes rotated in platelet-red cell suspensions has been measured.
(16) A 2.7-kilobase DNA fragment carrying the entire exotoxin A (ETA) structural gene was divided into three nonoverlapping probes.
(17) The indication of the DNA probe method would be considered in the four cases as follows, 1. necessity of the special equipment to isolate the pathogen, 2. necessity of the long period to isolate the pathogen, 3. existence of the cross reaction among the pathogen and relative organisms in the immunological procedure, 4. existence of the difficulty to identify the species of the pathogen by the ordinary procedure.
(18) Slight cross-reactivity was apparent when crude preparations of cellular or culture filtrate antigens, used in this laboratory to detect antibodies to Candida albicans, Coccidioides immitis and Cryptococcus neoformans, were probed with hyperimmune rabbit antisera to A. fumigatus.
(19) The results, together with the known geometry of the enzyme, indicate that active site probes in the dodecamer are widely separated and that energy transfer occurs from a single donor to two or three acceptors on adjacent subunits.
(20) The availability of locus-specific probes should significantly expand the role of minisatellite markers in population biology.
Prod
Definition:
(n.) A pointed instrument for pricking or puncturing, as a goad, an awl, a skewer, etc.
(n.) A prick or stab which a pointed instrument.
(n.) A light kind of crossbow; -- in the sense, often spelled prodd.
(v. t.) To thrust some pointed instrument into; to prick with something sharp; as, to prod a soldier with a bayonet; to prod oxen; hence, to goad, to incite, to worry; as, to prod a student.
Example Sentences:
(1) Anatomists involved with studies of the hippocampal formation are being prodded by computational modelers and physiologists who demand detailed and quantitative information concerning hippocampal neurons and circuits.
(2) When exposed to the nonelectrified prod after 24 h, total burying time was reduced in the 2mA group but still significantly longer than in the 0mA group.
(3) New Jersey environmentalists credit Jackson with prodding Governor Jon Corzine to adopt environmentally friendly policies.
(4) Both in the presence and absence of bedding material, rats explored the nonelectrified prod and showed a small increase in plasma NA and CS contents.
(5) While the Nexus One's single-finger prodding works well enough, there's none of the pinching action to zoom into maps and photographs that makes the iPhone feel so advanced, nor its realistic-feel friction.
(6) Barratt, a housebuilder not always associated with design quality, has built the St Andrews and Barrier Park projects in east London, albeit only after prodding from the London Development Agency, the public body that sold it the land.
(7) Unfortunately for the assembled crowds, Ting kept his powder dry, despite much prodding and questioning, revealing nothing about the year's worth of data from AMS except to say that they would be "important" results and would be made public when he submitted them to a scientific journal within a few weeks.
(8) Lamine Koné pounced on a knockdown from Jan Kirchhoff in the penalty area, evaded a tackle and squared for the substitute to prod home from seven yards and prompt scenes of unbridled jubilation in the away end.
(9) Olsson, totally unmarked, had the simple task of prodding over the line.
(10) Stun guns, shock batons and cattle prods are electric shock devices which can be used as weapons against the human body.
(11) While the degree of anxiety is measured by burying behavior, elicited by the novelty of prod shock, immobility was the prevalent response of WKY rats.
(12) Cut through the fine print and this is the bottom line: p eople with children over the age of six will be prodded back into the workforce.
(13) In microsomal fractions, enzyme activities measured were pentoxyresorufin O-dealkylase (PROD), ethoxyresorufin O-dealkylase (EROD), and epoxide hydrolase (mEH).
(14) They don't even get to go home for a sleep because dough requires contant prodding, waiting, more prodding and worrying.
(15) The enriched Clara cell fraction possessed (per 10(6) cells) greater P-450 and reduced GSH contents and higher enzyme activities (i.e., NADPH- and NADH cytochrome c reductases, benzyloxy (BROD)-, pentoxy (PROD)- and etoxyresorufin (EROD)-O-dealkylases, GSH transferase, GSH peroxidase, GSH reductase and NADPH quinone oxidoreductase) than either the enriched type II cell or endothelial cell preparations.
(16) UN officials said in advance they hoped new commitments from the big industrialised states, such as Japan and China, would prod other countries into action so that they not be seen as the spoilers of a potential deal at Copenhagen.
(17) It will need lots of tweaking to avoid annoying people – it's already being prodded to see whether it takes more or fewer clicks to reach the phone-dialer (more), and whether you can still set wallpaper (no, but your friends do with their picture – you may need to prune your friends).
(18) The Arsenal defender was caught in possession on the edge of the box by the striker Haris Tabakovic and he crossed for Kamberi who could only prod wide.
(19) Superstars where they attended college, hopefuls suddenly find themselves in unusual situations – as lambs in the middle of an Indianapolis field, being poked, prodded, measured and assessed; then as masters and conquerors, listening to famous GMs and coaches playing salesmen and extolling the virtues of their organisation.
(20) Funding for Lending lets the banks borrow billions at just 0.25% interest to prod them to loosen the purse strings, especially for first-time buyers who face huge hurdles when finding loans.