(v. t.) To examine, as a wound, an ulcer, or some cavity of the body, with a probe.
(v. t.) Fig.: to search to the bottom; to scrutinize or examine thoroughly.
(n.) An instrument for examining the depth or other circumstances of a wound, ulcer, or cavity, or the direction of a sinus, of for exploring for bullets, for stones in the bladder, etc.
(1) A series of human cDNA clones of various sizes and relative localizations to the mRNA molecule were isolated by using the human p53-H14 (2.35-kilobase) cDNA probe which we previously cloned.
(2) Theophylline kinetics, as an in vivo probe for the potentially toxic cytochrome P-450I pathway of drug metabolism, were studied in 11 healthy volunteers and 11 patients with calcific chronic pancreatitis at Madras, South India.
(3) Five probes of high specificity to individual chromosomes (chromosomes 3, 11, 17, 18 and X) were hybridized in situ to metaphase chromosomes of different individuals.
(4) In order to determine the extent of this similarity, I have developed a panel of probes for many of the Pacl restriction fragments and have shown that most of the Pacl and Notl fragments found in MBa are also present in MBb.
(5) The haplotype of the recombinant X chromosome of each of 241 backcross progeny has been established using the X-linked anchor loci Otc, Hprt, Dmd, Pgk-1, and Amg and the additional probes DXSmh43 and Cbx-rs1.
(6) Periodontal disease activity is defined clinically by progressive loss of probing attachment and radiographically by progressive loss of alveolar bone.
(7) The mean histamine level in the first 10-min sample following probe insertion was 39.4 nM.
(8) Five of them had a fast-moving Eco RI fragment 5.6 kb long that hybridized with zeta-specific probe but not with alpha-specific probe.
(9) We studied the haemodynamic (ultrasound Doppler flow probes) effects of synthetic atriopeptin II at natriuretic doses in conscious rats.
(10) DNA from 9% (47 of 529) of the E. coli colonies tested hybridized with the ST probe, whereas only 5% (28 of 529) produced ST as measured by the suckling mouse bioassay.
(11) Likewise, they had little or no effects on the fluorescence anisotropy of TMA-DPH, which is also thought to be located in the interfacial region of the lipid bilayer, either when the probe was located in the outer layer of the plasma membrane or when the probe was located in the inner membrane compartment.
(12) Sequence specific binding of protein extracts from 13 different yeast species to three oligonucleotide probes and two points mutants derived from Saccharomyces cerevisiae DNA binding proteins were tested using mobility shift assays.
(13) The probe has been used for the identification of new Legionella-like strains isolated from the environment.
(14) Therefore, we conclude this is a bovine DR beta-like pseudogene, BoDR beta I. Exon-containing regions have been used as probes in Southern blot analyses of bovine genomic DNA digested with EcoRI.
(15) The adherence of 51Cr-labeled platelets to rabbit aortae everted on probes rotated in platelet-red cell suspensions has been measured.
(16) A 2.7-kilobase DNA fragment carrying the entire exotoxin A (ETA) structural gene was divided into three nonoverlapping probes.
(17) The indication of the DNA probe method would be considered in the four cases as follows, 1. necessity of the special equipment to isolate the pathogen, 2. necessity of the long period to isolate the pathogen, 3. existence of the cross reaction among the pathogen and relative organisms in the immunological procedure, 4. existence of the difficulty to identify the species of the pathogen by the ordinary procedure.
(18) Slight cross-reactivity was apparent when crude preparations of cellular or culture filtrate antigens, used in this laboratory to detect antibodies to Candida albicans, Coccidioides immitis and Cryptococcus neoformans, were probed with hyperimmune rabbit antisera to A. fumigatus.
(19) The results, together with the known geometry of the enzyme, indicate that active site probes in the dodecamer are widely separated and that energy transfer occurs from a single donor to two or three acceptors on adjacent subunits.
(20) The availability of locus-specific probes should significantly expand the role of minisatellite markers in population biology.
(a.) Bending forward; inclined; not erect.
(a.) Prostrate; flat; esp., lying with the face down; -- opposed to supine.
(a.) Headlong; running downward or headlong.
(a.) Sloping, with reference to a line or surface; declivous; inclined; not level.
(a.) Inclined; propense; disposed; -- applied to the mind or affections, usually in an ill sense. Followed by to.
(1) Anhidrotic ectodermal dysplasia is characterized by an absence of seromucous glands in the oropharynx and tracheobronchial tree, making children with this disease prone to viral and bacterial respiratory infections.
(2) Moreover, the mucoid substances of the sensillum lymph are probably involved in water conservation, since sensilla are prone to water loss, because the overlying cuticle must be permeable to the chemical stimuli.
(3) Analysis of mice injected with helper-free P90A virus stocks demonstrates that the variants are generated during viral replication in vivo, probably as a consequence of error-prone reverse transcription.
(4) The effects of chronic dietary salt-loading and nifedipine therapy on hypertension-prone (SBH), -resistant (SBN) and parental (SB) Sabra rats were investigated.
(5) The major behavioural assessment was the Jenkins Activity Survey (JAS) designed to measure the coronary-prone behaviour pattern (Type A).
(6) In 25 patients we evaluated the efficacy of the prone position to counter these technical difficulties and found that the prone position offers visualization superior to the supine, especially in obese and uncooperative patients and those with abundant bowel gas.
(7) However, nonsuppression in the dexamethasone suppression test was not specifically associated with the pain-prone disorder, which was further characterized by the factor models of the Hamilton Depression Scale.
(8) Advancing age was associated with a reduction in cell proliferative responses to PHA in both substrains, although the rate of decline was significantly more rapid in the senescence-prone animals.
(9) Surviving cells show such cancer-prone genetic consequences.
(10) Aneurysms enlarge rapidly when coupled with infection and are prone to rupture, thus requiring extensive surgical repair.
(11) Asymmetrical gait pattern with mild gait disturbance was found more often in infants lying in supine than in prone.
(12) Using a biopsy procedure, splenic pancreas was removed from both 65 and from 80 day old diabetes prone BB rats.
(13) However, DIO-prone [3H]PAC binding was only 14-39% of DR-prone levels in 9 areas including 4 amygdalar nuclei, the lateral area, dorso- and ventromedial nuclei of the hypothalamus, median eminence and medial dorsal thalamic n. Although it is unclear whether this widespread decrease in [3H]PAC binding implicates brain alpha 2-adrenoceptors in the pathophysiology of DIO, it does correlate with a phenotypic marker (increase glucose-induced NE release) which predicts the subsequent development of DIO on a high-energy diet.
(14) The effect of varying amounts of dietary magnesium in conjunction with potassium (K) on hypertension and stroke mortality in hypertensive stroke prone (SHRsp) rats was studied.
(15) The results indicate the beta-globin domain is a mosaic of aggregation-resistant and aggregation-prone regions with the latter being associated with H1 and H5.
(16) Under the influence of immunosuppression cutaneous hyperkeratoses more rapidly evolve into squamous-cell carcinoma, multiple skin cancers occur in some patients, and keratoacanthoma is not only more frequent but also prone to early recurrence.
(17) This chromosome region in T cells is unusually prone to develop breaks in vivo, perhaps reflecting instability generated by somatic rearrangement of T-cell receptor genes during normal differentiation in this cell lineage.
(18) These data suggest that the error-prone repair pathway participates in mutagenesis by quercetin and its metabolites.
(19) The City is rife with gambling addicts whose habits contribute to a risk-prone culture of the sort which helped Kweku Adoboli lose UBS £1.5bn, according to one London trader.
(20) The spontaneously diabetic BB rat syndrome is associated with a marked lymphopenia, which affects all members of litters of diabetes-prone rats, and may be a necessary condition for the development of the disease.