(v. t.) To examine, as a wound, an ulcer, or some cavity of the body, with a probe.
(v. t.) Fig.: to search to the bottom; to scrutinize or examine thoroughly.
(n.) An instrument for examining the depth or other circumstances of a wound, ulcer, or cavity, or the direction of a sinus, of for exploring for bullets, for stones in the bladder, etc.
Example Sentences:
(1) A series of human cDNA clones of various sizes and relative localizations to the mRNA molecule were isolated by using the human p53-H14 (2.35-kilobase) cDNA probe which we previously cloned.
(2) Theophylline kinetics, as an in vivo probe for the potentially toxic cytochrome P-450I pathway of drug metabolism, were studied in 11 healthy volunteers and 11 patients with calcific chronic pancreatitis at Madras, South India.
(3) Five probes of high specificity to individual chromosomes (chromosomes 3, 11, 17, 18 and X) were hybridized in situ to metaphase chromosomes of different individuals.
(4) In order to determine the extent of this similarity, I have developed a panel of probes for many of the Pacl restriction fragments and have shown that most of the Pacl and Notl fragments found in MBa are also present in MBb.
(5) The haplotype of the recombinant X chromosome of each of 241 backcross progeny has been established using the X-linked anchor loci Otc, Hprt, Dmd, Pgk-1, and Amg and the additional probes DXSmh43 and Cbx-rs1.
(6) Periodontal disease activity is defined clinically by progressive loss of probing attachment and radiographically by progressive loss of alveolar bone.
(7) The mean histamine level in the first 10-min sample following probe insertion was 39.4 nM.
(8) Five of them had a fast-moving Eco RI fragment 5.6 kb long that hybridized with zeta-specific probe but not with alpha-specific probe.
(9) We studied the haemodynamic (ultrasound Doppler flow probes) effects of synthetic atriopeptin II at natriuretic doses in conscious rats.
(10) DNA from 9% (47 of 529) of the E. coli colonies tested hybridized with the ST probe, whereas only 5% (28 of 529) produced ST as measured by the suckling mouse bioassay.
(11) Likewise, they had little or no effects on the fluorescence anisotropy of TMA-DPH, which is also thought to be located in the interfacial region of the lipid bilayer, either when the probe was located in the outer layer of the plasma membrane or when the probe was located in the inner membrane compartment.
(12) Sequence specific binding of protein extracts from 13 different yeast species to three oligonucleotide probes and two points mutants derived from Saccharomyces cerevisiae DNA binding proteins were tested using mobility shift assays.
(13) The probe has been used for the identification of new Legionella-like strains isolated from the environment.
(14) Therefore, we conclude this is a bovine DR beta-like pseudogene, BoDR beta I. Exon-containing regions have been used as probes in Southern blot analyses of bovine genomic DNA digested with EcoRI.
(15) The adherence of 51Cr-labeled platelets to rabbit aortae everted on probes rotated in platelet-red cell suspensions has been measured.
(16) A 2.7-kilobase DNA fragment carrying the entire exotoxin A (ETA) structural gene was divided into three nonoverlapping probes.
(17) The indication of the DNA probe method would be considered in the four cases as follows, 1. necessity of the special equipment to isolate the pathogen, 2. necessity of the long period to isolate the pathogen, 3. existence of the cross reaction among the pathogen and relative organisms in the immunological procedure, 4. existence of the difficulty to identify the species of the pathogen by the ordinary procedure.
(18) Slight cross-reactivity was apparent when crude preparations of cellular or culture filtrate antigens, used in this laboratory to detect antibodies to Candida albicans, Coccidioides immitis and Cryptococcus neoformans, were probed with hyperimmune rabbit antisera to A. fumigatus.
(19) The results, together with the known geometry of the enzyme, indicate that active site probes in the dodecamer are widely separated and that energy transfer occurs from a single donor to two or three acceptors on adjacent subunits.
(20) The availability of locus-specific probes should significantly expand the role of minisatellite markers in population biology.
Proof
Definition:
(n.) Any effort, process, or operation designed to establish or discover a fact or truth; an act of testing; a test; a trial.
(n.) That degree of evidence which convinces the mind of any truth or fact, and produces belief; a test by facts or arguments that induce, or tend to induce, certainty of the judgment; conclusive evidence; demonstration.
(n.) The quality or state of having been proved or tried; firmness or hardness that resists impression, or does not yield to force; impenetrability of physical bodies.
(n.) Firmness of mind; stability not to be shaken.
(n.) A trial impression, as from type, taken for correction or examination; -- called also proof sheet.
(n.) A process for testing the accuracy of an operation performed. Cf. Prove, v. t., 5.
(v. t.) Armor of excellent or tried quality, and deemed impenetrable; properly, armor of proof.
(a.) Used in proving or testing; as, a proof load, or proof charge.
(a.) Firm or successful in resisting; as, proof against harm; waterproof; bombproof.
(a.) Being of a certain standard as to strength; -- said of alcoholic liquors.
Example Sentences:
(1) Now, as the Senate takes up a weakened House bill along with the House's strengthened backdoor-proof amendment, it's time to put focus back on sweeping reform.
(2) Immunohistochemical insulin proofs were positive in the peritoneum over a period of 3 months and in the liver up to one year after implantation.
(3) Although histologic proof of regression is not available, this experience suggests a more favorable prognosis than previously thought possible.
(4) I never accuse a student of plagiarizing unless I have proof, almost always in the form of sources easily found by Googling a few choice phrases.
(5) The appearance of plasma cells suggests local maturation of B cells and represents a morphologic proof of local production of immunoglobulins.
(6) Sharif Mobley, 30, whose lawyers consider him to be disappeared, managed to call his wife in Philadelphia on Thursday, the first time they had spoken since February and a rare independent proof he is alive since a brief phone call with his mother in July.
(7) There is general agreement that suicides are likely to be undercounted, both for structural reasons (the burden-of-proof issue, the requirement that the coroner or medical examiner suspect the possibility of suicide) and for sociocultural reasons.
(8) At least Depay departed having had a shot on target, something his manager will probably offer as proof United are improving.
(9) And Pippi Longstocking, her most famous character, comes really close to being the personified proof of that… So where did Pippi come from?
(10) The data are presented in proof of the existence of different as well as common pathways for virus inhibiting effects of different preparations.
(11) Proof of the eye's potent antimicrobial environment was demonstrated.
(12) Agüero tried to retreive the situation – proof that City had more than enough finishers on hand to take advantage of momentary Burnley disarray – though, forced away from goal, he shot from a narrow angle and missed the target.
(13) These case histories, and very substantial background proof of efficacy and safety, justify treating with CoQ10 patients in failure awaiting transplantation.
(14) There's no doubt Twitter is, for those who are into that kind of thing, a first-class social networking medium (the proof: pretty much every other social networking site, including Facebook, has tried to buy it and, having failed, adopted a whole raft of blatantly Twitter-like features of their own).
(15) When the Washington Post reports a boom in bullet-proof backpacks for children, it is not a good time to be a resident of a place colloquially known as The Arms.
(16) Proof stress, ultimate tensile strength, elongation, and plastic stiffness have been measured and results compared by use of analyses of variance.
(17) Jonathan's party and the biggest opposition coalition have traded accusations about who is sponsoring and arming Boko Haram, but none have provided any proof.
(18) Many drugs have been proposed although the documentary proof of their efficacy varies.
(19) Fielding said: "He [Stewart] mentioned that on the day before the execution, when Allen was visited by his wife for the last time, they were separated by a piece of what was supposed to be bullet-proofed glass.
(20) He compared the situation to insider trading or corruption, in which there may not be direct proof of a criminal quid pro quo taking place, but where there is a pattern of behaviour that warrants attention.