(v. t.) To examine, as a wound, an ulcer, or some cavity of the body, with a probe.
(v. t.) Fig.: to search to the bottom; to scrutinize or examine thoroughly.
(n.) An instrument for examining the depth or other circumstances of a wound, ulcer, or cavity, or the direction of a sinus, of for exploring for bullets, for stones in the bladder, etc.
Example Sentences:
(1) A series of human cDNA clones of various sizes and relative localizations to the mRNA molecule were isolated by using the human p53-H14 (2.35-kilobase) cDNA probe which we previously cloned.
(2) Theophylline kinetics, as an in vivo probe for the potentially toxic cytochrome P-450I pathway of drug metabolism, were studied in 11 healthy volunteers and 11 patients with calcific chronic pancreatitis at Madras, South India.
(3) Five probes of high specificity to individual chromosomes (chromosomes 3, 11, 17, 18 and X) were hybridized in situ to metaphase chromosomes of different individuals.
(4) In order to determine the extent of this similarity, I have developed a panel of probes for many of the Pacl restriction fragments and have shown that most of the Pacl and Notl fragments found in MBa are also present in MBb.
(5) The haplotype of the recombinant X chromosome of each of 241 backcross progeny has been established using the X-linked anchor loci Otc, Hprt, Dmd, Pgk-1, and Amg and the additional probes DXSmh43 and Cbx-rs1.
(6) Periodontal disease activity is defined clinically by progressive loss of probing attachment and radiographically by progressive loss of alveolar bone.
(7) The mean histamine level in the first 10-min sample following probe insertion was 39.4 nM.
(8) Five of them had a fast-moving Eco RI fragment 5.6 kb long that hybridized with zeta-specific probe but not with alpha-specific probe.
(9) We studied the haemodynamic (ultrasound Doppler flow probes) effects of synthetic atriopeptin II at natriuretic doses in conscious rats.
(10) DNA from 9% (47 of 529) of the E. coli colonies tested hybridized with the ST probe, whereas only 5% (28 of 529) produced ST as measured by the suckling mouse bioassay.
(11) Likewise, they had little or no effects on the fluorescence anisotropy of TMA-DPH, which is also thought to be located in the interfacial region of the lipid bilayer, either when the probe was located in the outer layer of the plasma membrane or when the probe was located in the inner membrane compartment.
(12) Sequence specific binding of protein extracts from 13 different yeast species to three oligonucleotide probes and two points mutants derived from Saccharomyces cerevisiae DNA binding proteins were tested using mobility shift assays.
(13) The probe has been used for the identification of new Legionella-like strains isolated from the environment.
(14) Therefore, we conclude this is a bovine DR beta-like pseudogene, BoDR beta I. Exon-containing regions have been used as probes in Southern blot analyses of bovine genomic DNA digested with EcoRI.
(15) The adherence of 51Cr-labeled platelets to rabbit aortae everted on probes rotated in platelet-red cell suspensions has been measured.
(16) A 2.7-kilobase DNA fragment carrying the entire exotoxin A (ETA) structural gene was divided into three nonoverlapping probes.
(17) The indication of the DNA probe method would be considered in the four cases as follows, 1. necessity of the special equipment to isolate the pathogen, 2. necessity of the long period to isolate the pathogen, 3. existence of the cross reaction among the pathogen and relative organisms in the immunological procedure, 4. existence of the difficulty to identify the species of the pathogen by the ordinary procedure.
(18) Slight cross-reactivity was apparent when crude preparations of cellular or culture filtrate antigens, used in this laboratory to detect antibodies to Candida albicans, Coccidioides immitis and Cryptococcus neoformans, were probed with hyperimmune rabbit antisera to A. fumigatus.
(19) The results, together with the known geometry of the enzyme, indicate that active site probes in the dodecamer are widely separated and that energy transfer occurs from a single donor to two or three acceptors on adjacent subunits.
(20) The availability of locus-specific probes should significantly expand the role of minisatellite markers in population biology.
Prove
Definition:
(v. t.) To try or to ascertain by an experiment, or by a test or standard; to test; as, to prove the strength of gunpowder or of ordnance; to prove the contents of a vessel by a standard measure.
(v. t.) To evince, establish, or ascertain, as truth, reality, or fact, by argument, testimony, or other evidence.
(v. t.) To ascertain or establish the genuineness or validity of; to verify; as, to prove a will.
(v. t.) To gain experience of the good or evil of; to know by trial; to experience; to suffer.
(v. t.) To test, evince, ascertain, or verify, as the correctness of any operation or result; thus, in subtraction, if the difference between two numbers, added to the lesser number, makes a sum equal to the greater, the correctness of the subtraction is proved.
(v. t.) To take a trial impression of; to take a proof of; as, to prove a page.
(v. i.) To make trial; to essay.
(v. i.) To be found by experience, trial, or result; to turn out to be; as, a medicine proves salutary; the report proves false.
(v. i.) To succeed; to turn out as expected.
Example Sentences:
(1) During the performance of propulsive waves of the oesophagus the implanted vagus nerve caused clonic to tetanic contractions of the sternohyoid muscle, thus proving the oesophagomotor genesis of the reinnervating nerve fibres.
(2) Treatment termination due to lack of efficacy or combined insufficient therapeutic response and toxicity proved to be influenced by the initial disease activity and by the rank order of prescription.
(3) "The Samaras government has proved to be dangerous; it cannot continue handling the country's fate."
(4) 119 representatives of this population were checked in their sexual contacts; of these, 13 persons proved to be infected with HIV.
(5) Basing the prediction of student performance in medical school on intellective-cognitive abilities alone has proved to be more pertinent to academic achievement than to clinical practice.
(6) Well tolerated from the clinical and laboratory points of view, it proved remarkably effective.
(7) It arguably became too comfortable for Rodgers' team, with complacency and slack defending proving a dangerous brew.
(8) She was organised, good with people, very grown up and quickly proved herself to be indispensable.
(9) Proving that not all teens are content with being part of a purely digital community, Adele Mayr attended a YouTube meet-up in London’s Hyde Park.
(10) Gamma-irradiated splenic homogenates of armadillos infected with M. leprae proved sterile by conventional tests and media.
(11) None of the compounds proved active against the replication of retroviruses (human immunodeficiency virus, murine sarcoma virus) at concentrations that were not toxic to the host cells.
(12) A polypotent mechanism of the stimulating effect of fibronectin instillations during all the stages of the reparative process in the corneal tissue was proved.
(13) Platelet survival time in patients with Crohn's disease proved to be significantly shortened (p less than 0.001), whereas platelet turnover appeared augmented.
(14) The data obtained from all groups proved to be consistent.
(15) A newborn presenting with persistent umbilical stump bleeding should be screened for factor XIII deficiency when routine coagulation tests prove normal.
(16) Treatment was monitored by simple measurements, and it's toxicity proved to be scanty.
(17) The resistance proved to be directly dependent upon the specific antisense RNA and to be inversely proportional to the multiplicity of infecting polyoma.
(18) Accordingly, LPA proved an extremely stable characteristic which did not show any substantial variations in the course of five years.
(19) The obtained protein fraction proved to be a glycoprotein according to the positive staining with periodic acid Schiff.
(20) The consequences of proved hypersensitivity in patients with metal-to-plastic prostheses, either present prior to insertion of the prosthesis or evoked by the implant material, are not known.