(v. t.) To examine, as a wound, an ulcer, or some cavity of the body, with a probe.
(v. t.) Fig.: to search to the bottom; to scrutinize or examine thoroughly.
(n.) An instrument for examining the depth or other circumstances of a wound, ulcer, or cavity, or the direction of a sinus, of for exploring for bullets, for stones in the bladder, etc.
Example Sentences:
(1) A series of human cDNA clones of various sizes and relative localizations to the mRNA molecule were isolated by using the human p53-H14 (2.35-kilobase) cDNA probe which we previously cloned.
(2) Theophylline kinetics, as an in vivo probe for the potentially toxic cytochrome P-450I pathway of drug metabolism, were studied in 11 healthy volunteers and 11 patients with calcific chronic pancreatitis at Madras, South India.
(3) Five probes of high specificity to individual chromosomes (chromosomes 3, 11, 17, 18 and X) were hybridized in situ to metaphase chromosomes of different individuals.
(4) In order to determine the extent of this similarity, I have developed a panel of probes for many of the Pacl restriction fragments and have shown that most of the Pacl and Notl fragments found in MBa are also present in MBb.
(5) The haplotype of the recombinant X chromosome of each of 241 backcross progeny has been established using the X-linked anchor loci Otc, Hprt, Dmd, Pgk-1, and Amg and the additional probes DXSmh43 and Cbx-rs1.
(6) Periodontal disease activity is defined clinically by progressive loss of probing attachment and radiographically by progressive loss of alveolar bone.
(7) The mean histamine level in the first 10-min sample following probe insertion was 39.4 nM.
(8) Five of them had a fast-moving Eco RI fragment 5.6 kb long that hybridized with zeta-specific probe but not with alpha-specific probe.
(9) We studied the haemodynamic (ultrasound Doppler flow probes) effects of synthetic atriopeptin II at natriuretic doses in conscious rats.
(10) DNA from 9% (47 of 529) of the E. coli colonies tested hybridized with the ST probe, whereas only 5% (28 of 529) produced ST as measured by the suckling mouse bioassay.
(11) Likewise, they had little or no effects on the fluorescence anisotropy of TMA-DPH, which is also thought to be located in the interfacial region of the lipid bilayer, either when the probe was located in the outer layer of the plasma membrane or when the probe was located in the inner membrane compartment.
(12) Sequence specific binding of protein extracts from 13 different yeast species to three oligonucleotide probes and two points mutants derived from Saccharomyces cerevisiae DNA binding proteins were tested using mobility shift assays.
(13) The probe has been used for the identification of new Legionella-like strains isolated from the environment.
(14) Therefore, we conclude this is a bovine DR beta-like pseudogene, BoDR beta I. Exon-containing regions have been used as probes in Southern blot analyses of bovine genomic DNA digested with EcoRI.
(15) The adherence of 51Cr-labeled platelets to rabbit aortae everted on probes rotated in platelet-red cell suspensions has been measured.
(16) A 2.7-kilobase DNA fragment carrying the entire exotoxin A (ETA) structural gene was divided into three nonoverlapping probes.
(17) The indication of the DNA probe method would be considered in the four cases as follows, 1. necessity of the special equipment to isolate the pathogen, 2. necessity of the long period to isolate the pathogen, 3. existence of the cross reaction among the pathogen and relative organisms in the immunological procedure, 4. existence of the difficulty to identify the species of the pathogen by the ordinary procedure.
(18) Slight cross-reactivity was apparent when crude preparations of cellular or culture filtrate antigens, used in this laboratory to detect antibodies to Candida albicans, Coccidioides immitis and Cryptococcus neoformans, were probed with hyperimmune rabbit antisera to A. fumigatus.
(19) The results, together with the known geometry of the enzyme, indicate that active site probes in the dodecamer are widely separated and that energy transfer occurs from a single donor to two or three acceptors on adjacent subunits.
(20) The availability of locus-specific probes should significantly expand the role of minisatellite markers in population biology.
Quest
Definition:
(n.) The act of seeking, or looking after anything; attempt to find or obtain; search; pursuit; as, to rove in quest of game, of a lost child, of property, etc.
(n.) Request; desire; solicitation.
(n.) Those who make search or inquiry, taken collectively.
(n.) Inquest; jury of inquest.
(n.) To search for; to examine.
(v. i.) To go on a quest; to make a search; to go in pursuit; to beg.
Example Sentences:
(1) The Broken King by Philip Womack Photograph: Troika Books The Sword in the Stone begins with Wart on a "quest" to find a tutor.
(2) Alternative interpretations of these investigations, however, suggest important hypotheses for further research in our quest to understand information-processing deficits associated with schizophrenia.
(3) At the time, he described his scientific quest by gesturing to the ocean: "We're just trying to figure out who fucking lives out there."
(4) Lula responded by insisting that his government would not stray from its quest to protect the Amazon and appointed another high-profile environmentalist, Green party founder Carlos Minc, as his new minister.
(5) The American president at the time, George HW Bush, captured the mood well in his September 1990 address to Congress when he articulated his vision of a “new world order … freer from the threat of terror, stronger in the pursuit of justice, and more secure in the quest for peace”.
(6) While it is not directly related to the name issue, the plaintiffs were hoping that Abe’s quest to raise the profile of women in the workplace would help their cause.
(7) I can’t see they’d be able to ameliorate this.” Malcolm Turnbull’s quest for power leaves him at odds with the electorate | Peter Lewis Read more Xenophon said the aspects of the plebiscite that troubled him were the cost, the amount of “national oxygen” spent on the issue and its non-binding nature.
(8) There’s a lot to break down with the NCAA Tournament, what with 68 teams playing a tournament that lasts several weeks, but this FAQ should at least clear a few things up about college basketball’s month-long quest to crown a champion.
(9) The country’s post-Soviet history has been defined by two diplomatic disputes with its neighbours: a quest to get Turkey to agree that the massacre of hundreds of thousands of Armenians during the late Ottoman era constituted genocide; and the search for a political settlement to a conflict with Azerbaijan over the Nagorno-Karabakh territory .
(10) A suppression of questing activity with increased ambient temperature was evident at the highest observed temperatures, implying an upper temperature limit for this activity.
(11) Evidently fuelled by the agony of losing a series twelve months ago when the trophy was almost within their grasp, they also had the teamwork, technique and experience to turn their quest for revenge into a reality.
(12) With Ukip's clear "in-out" referendum pledge snapping at his heels and devastation beckoning at this year's European elections, Cameron needs a form of words that honours his quest for European reform while calming his party.
(13) Most ticks (99%) used grass as questing sites at a height of approximately 45 cm (range 10-97 cm), which correlates with the size of host animals.
(14) The quest for a deal in Paris is intensifying, according to Laurence Tubiana, the French ambassador for climate change, speaking during a Google hangout on Friday .
(15) In view of the results of CAST, researchers working in the field of experimental arrhythmia have been increasingly focusing on the quest for new anti-arrhythmic modes of action and ways of detecting pro-arrhythmic properties of antiarrhythmic drugs at an early stage.
(16) Here's what happened the last time these two sides played here in mid-October: Facebook Twitter Pinterest Share Share this post Facebook Twitter Pinterest close 3.27am GMT Preamble Hello, and welcome to the Western Conference semi-final second leg between Portland Timbers and Seattle Sounders , in which Portland try to defend a slim lead and Seattle continue their annual quest to make a second leg playoff comeback actually count.
(17) She put herself above everyone else.” Ultimately, Mayer failed in her impossible quest.
(18) Not because of a statistical quest to have every school an academy, but because the academy in which you work will be part of a wider family and the independence this brings creates opportunity for innovation and choice.” The Department for Education defended the changes facing primary schools.
(19) "Saturday nights are the World Cup finals for people who create TV formats – it's still the most exciting quest there is – and the premium on new ideas and the next big thing is even higher.
(20) In their quest to avoid relegation from the Premier League, Sunderland Association Football Club have appointed a self-declared fascist as manager .