(v. t.) To examine, as a wound, an ulcer, or some cavity of the body, with a probe.
(v. t.) Fig.: to search to the bottom; to scrutinize or examine thoroughly.
(n.) An instrument for examining the depth or other circumstances of a wound, ulcer, or cavity, or the direction of a sinus, of for exploring for bullets, for stones in the bladder, etc.
Example Sentences:
(1) A series of human cDNA clones of various sizes and relative localizations to the mRNA molecule were isolated by using the human p53-H14 (2.35-kilobase) cDNA probe which we previously cloned.
(2) Theophylline kinetics, as an in vivo probe for the potentially toxic cytochrome P-450I pathway of drug metabolism, were studied in 11 healthy volunteers and 11 patients with calcific chronic pancreatitis at Madras, South India.
(3) Five probes of high specificity to individual chromosomes (chromosomes 3, 11, 17, 18 and X) were hybridized in situ to metaphase chromosomes of different individuals.
(4) In order to determine the extent of this similarity, I have developed a panel of probes for many of the Pacl restriction fragments and have shown that most of the Pacl and Notl fragments found in MBa are also present in MBb.
(5) The haplotype of the recombinant X chromosome of each of 241 backcross progeny has been established using the X-linked anchor loci Otc, Hprt, Dmd, Pgk-1, and Amg and the additional probes DXSmh43 and Cbx-rs1.
(6) Periodontal disease activity is defined clinically by progressive loss of probing attachment and radiographically by progressive loss of alveolar bone.
(7) The mean histamine level in the first 10-min sample following probe insertion was 39.4 nM.
(8) Five of them had a fast-moving Eco RI fragment 5.6 kb long that hybridized with zeta-specific probe but not with alpha-specific probe.
(9) We studied the haemodynamic (ultrasound Doppler flow probes) effects of synthetic atriopeptin II at natriuretic doses in conscious rats.
(10) DNA from 9% (47 of 529) of the E. coli colonies tested hybridized with the ST probe, whereas only 5% (28 of 529) produced ST as measured by the suckling mouse bioassay.
(11) Likewise, they had little or no effects on the fluorescence anisotropy of TMA-DPH, which is also thought to be located in the interfacial region of the lipid bilayer, either when the probe was located in the outer layer of the plasma membrane or when the probe was located in the inner membrane compartment.
(12) Sequence specific binding of protein extracts from 13 different yeast species to three oligonucleotide probes and two points mutants derived from Saccharomyces cerevisiae DNA binding proteins were tested using mobility shift assays.
(13) The probe has been used for the identification of new Legionella-like strains isolated from the environment.
(14) Therefore, we conclude this is a bovine DR beta-like pseudogene, BoDR beta I. Exon-containing regions have been used as probes in Southern blot analyses of bovine genomic DNA digested with EcoRI.
(15) The adherence of 51Cr-labeled platelets to rabbit aortae everted on probes rotated in platelet-red cell suspensions has been measured.
(16) A 2.7-kilobase DNA fragment carrying the entire exotoxin A (ETA) structural gene was divided into three nonoverlapping probes.
(17) The indication of the DNA probe method would be considered in the four cases as follows, 1. necessity of the special equipment to isolate the pathogen, 2. necessity of the long period to isolate the pathogen, 3. existence of the cross reaction among the pathogen and relative organisms in the immunological procedure, 4. existence of the difficulty to identify the species of the pathogen by the ordinary procedure.
(18) Slight cross-reactivity was apparent when crude preparations of cellular or culture filtrate antigens, used in this laboratory to detect antibodies to Candida albicans, Coccidioides immitis and Cryptococcus neoformans, were probed with hyperimmune rabbit antisera to A. fumigatus.
(19) The results, together with the known geometry of the enzyme, indicate that active site probes in the dodecamer are widely separated and that energy transfer occurs from a single donor to two or three acceptors on adjacent subunits.
(20) The availability of locus-specific probes should significantly expand the role of minisatellite markers in population biology.
Scrutiny
Definition:
(n.) Close examination; minute inspection; critical observation.
(n.) An examination of catechumens, in the last week of Lent, who were to receive baptism on Easter Day.
(n.) A ticket, or little paper billet, on which a vote is written.
(n.) An examination by a committee of the votes given at an election, for the purpose of correcting the poll.
(v. t.) To scrutinize.
Example Sentences:
(1) That is why you will be held relentlessly to account for those choices; why what you said in February invites forensic scrutiny.
(2) A role for cAMP in the process of LHRH release was suggested several years ago, but only recently has the validity of this notion come under close scrutiny.
(3) Even so, the controversy over the last assessment, and the political polarisation in America and other countries around climate science and the need for climate action, have created an additional layer of scrutiny around next week's report.
(4) Recommendations are made suggesting closer scrutiny of this region of the spine.
(5) This proposal is a purely partisan move that will backfire on the government disastrously.” The Green party accused Osborne of making “efforts to limit the democratic scrutiny of his austerity agenda”.
(6) Trump and Hillary Clinton’s dismal honesty ratings, he says, show scrutiny is working.
(7) Lord Thomson of Monifieth , the now deceased chairman of the political honours scrutiny committee, was a former Labour minister but then sat in the Lords as a Liberal Democrat peer.
(8) The surgical modality used was the modified Widman flap operation and the pockets under scrutiny were those with an initial probing depth of 4-6 mm.
(9) Over the last few days a former member of parliament's intelligence and security committee, Lord King, a former director of GCHQ, Sir David Omand, and a former director general of MI5, Dame Stella Rimington, have questioned whether the agencies need to be more transparent and accept more rigorous scrutiny of their work.
(10) "There is understandable scrutiny on how we are doing things and that should act as a conduit to look at labor issues across the region.
(11) In most developing countries abortion is illegal, and scrutiny of hospital records on complication (a 49% rate in a study in Latin America and 46% hospitalization) is a source.
(12) There is all sorts of opacity which makes it easy for an employee to suffer retaliation.” Despite recent reforms to improve transparency and accountability, the organisation remains impervious to public scrutiny, with no established mechanism for freedom of information – a right which more than 100 governments around the world have enshrined in law, and is openly advocated by UN bodies such as Unesco.
(13) Those seeking to stop the project contend that the $997m joint venture, signed in May 2010, did not undergo parliamentary scrutiny because it was concluded under the previous military regime.
(14) It is essential, therefore, to submit one's loyalties and value judgments to constant scrutiny and questioning and to those theological criteria that make abortion also (though not only) a theological question, a task not without its risks.
(15) But the damage from the whole affair and inevitable scrutiny of her successor might just mean they take a more even-handed approach to the job.
(16) WikiLeaks has demanded that Google and Facebook reveal which of their users are under similar scrutiny.
(17) Reacting to the announcement of the government review, Lady Smith of Basildon, the shadow leader of the Lords, said: “This is a massive over-reaction from a prime minister that clearly resents any challenge or meaningful scrutiny.
(18) But when they show up in Manchester at lunchtime on Tuesday to take part in a Conservative conference fringe meeting entitled Challenges for the EU in 2010, they may find themselves under the kind of scrutiny they rarely face at home.
(19) On the back of the disclosures, President Obama ordered a White House review into data surveillance , a number of congressional reform bills have been introduced, and protections have begun to be put in place to safeguard privacy for foreign leaders and to increase scrutiny over the NSA’s mass data collection.
(20) Alternative taxonomic structures require careful scrutiny and comparison to establish whether one structure will meet the needs of the profession or whether multiple structures of nursing diagnoses relative to outcomes are required.