(a.) Broken down in respect of rectitude, principle, virtue, or decency; openly and shamelessly immoral or vicious; dissolute; as, profligate man or wretch.
(n.) An abandoned person; one openly and shamelessly vicious; a dissolute person.
(v. t.) To drive away; to overcome.
Example Sentences:
(1) But this is not to say that I do not have a working knowledge of true bedsitters - and yes, they do still exist, in spite of estate agents' profligate use of the term 'studio flat'.
(2) But it relies too much on the myth that booms enrich everyone, a myth easily exposed by pointing out that under that supposedly profligate Labour administration, now accused of recklessly taking from the rich and giving to the poor, the gap between the richest and the poorest didn't narrow.
(3) "With a 53 per cent increase in energy consumption forecast by 2035, those who are commercially savvy will recognise that in a resource poor future, we cannot be captured by a profligate economic model from the past.
(4) Reasonable use” sounds … well, reasonable, but a “use it or lose it” clause incentivizes profligate use: if you don’t use your historic water allocation in a beneficial way, you forfeit your water rights, Gray said.
(5) The coalition succeeded an unbelievably profligate government that took state spending from 34% of GDP to over 45% in a decade .
(6) Other critics say low water prices are the culprits as they result in profligate water use and low investment in water-efficient infrastructure.
(7) All the debt ceiling ends up becoming is a political football used by the opposition party to suggest the government are profligate spenders.
(8) He believes that Osborne's decision to veto the measures in February shows that the Tories want to put spending cuts ahead of tackling child poverty as he seeks to depict Labour as profligate.
(9) The credit crunch hit, which might have been terminal to a project so palpably of the profligate boom years, but then the cavalry appeared, in the form of the property arm of the ruling family of Qatar.
(10) Thatcherism liked to present itself as a rejection of the postwar, state-driven, more profligate way of doing things.
(11) There is no reason why a constitutional solution that involves debt limitation should not command a large measure of public acceptance, especially in debtor countries, which have experienced the political and economic damage caused by previous profligate governments.
(12) In Brussels, right-of-centre German economists, who until recently dominated the European Central Bank's main decision-making board, lobbied for a "can't-pay, won't-pay" stance towards southern European countries seen as profligate spenders who need to understand the moral hazard of raising their living standards on a mountain of debt.
(13) The latest shock wave has served to ram home the reality that this remains first of all a crisis of the banks and the private sector – not, as the British government would have it, of profligate governments and public debt, which only ballooned to fill the gap left by market failure.
(14) Election officials have also disqualified Raja Pervaiz Ashraf, the man who until just a few weeks ago was the country's prime minister, under articles ensuring candidates are, among many other things, "sagacious, righteous and non-profligate".
(15) As inspectors from Brussels demanded answers this week from the Spanish government about how it plans to bring profligate regional governments under control, senior officials admitted they were clueless as to the real size of the debt in the biggest region – party-loving Andalucía.
(16) "People have far more confidence in Britain than in many other western countries who have got into trouble through profligate economic policies," he said.
(17) London, which has less annual rainfall than cities such as Athens and Sydney, is classed as "seriously water-stressed" by the Environment Agency , but critics of the Beckton plant – including former mayor of London Ken Livingstone – told the inquiry that desalination was energy-profligate, unnecessary and unsustainable.
(18) More and more people feel the gap between the profligate promises of individual freedom and sovereignty, and the incapacity of their political and economic organisations to realise them.
(19) His party has no members of parliament, a situation unlikely to change at the next election, and offers promiscuous and profligate policies that add up to errant nonsense as a platform for government.
(20) That debacle shows the Conservatives as being as profligate as sailors on shore leave.
Prolific
Definition:
(a.) Having the quality of generating; producing young or fruit; generative; fruitful; productive; -- applied to plants producing fruit, animals producing young, etc.; -- usually with the implied idea of frequent or numerous production; as, a prolific tree, female, and the like.
(a.) Serving to produce; fruitful of results; active; as, a prolific brain; a controversy prolific of evil.
(a.) Proliferous.
Example Sentences:
(1) The telencephalic proliferative response has been studied in adult newts after lesion on the central nervous system.
(2) Research efforts in the Swedish schools are of high quality and are remarkably prolific.
(3) The effect of mycobacterial phenolic glycolipids from Mycobacterium leprae, M. bovis BCG, and M. kansasii on in vitro proliferative responses by human blood mononuclear cells from healthy BCG vaccinees was investigated.
(4) In the fimbria a significantly higher concentration (P less than 0.01) was observed in the proliferative phase.
(5) Confirming a low proliferative activity in CN and a high activity in melanomas (MIS, IM, MM), the results showed that dysplastic nevi (NAA, NCAA) had a proliferative activity intermediate between common nevi and melanomas.
(6) The mixed leukocyte reaction proliferative response against the B7 transfectant is inhibited by either anti-CD28 or B7 mAb.
(7) Following BHT administration, the alveolar stem cells (type II pneumocytes) proliferate and differentiate according to a biphasic pattern, with proliferative peaks at d 3 and 7.
(8) At autopsy, this DOCA-hypertensive rat was found to have a form of hepatitis associated with proliferative activity, i.e., cellular unrest, mitotic figures and oval cell hyperplasia.
(9) There was no significant difference in sialic acid concentration in the uterus during the proliferative and luteal phases of the menstrual cycle.
(10) To find out whether the deeper inhibition of replicative activity in ventricular myocytes influences fibroblasts and endothelial cells from ventricles, the proliferative activity of non-muscle cells was studied.
(11) We infer from these results that endotoxin ameliorates the cyclical changes in blood cell counts by regulating hematopoietic proliferative activity at the stem cell level.
(12) In diabetic patients with proliferative retinopathy, K was lower (P less than 0.05) than in diabetic patients without retinopathy.
(13) We suggest that radiation-induced specific chromosome 2 rearrangement associated with IL-1 beta deregulation may initiate murine leukemogenesis through the uncoupling of normal proliferative control mechanisms in multipotential hemopoietic cells.
(14) However, cytophotometric DNA analysis disclosed that significant increases in proliferative activity of mucosa had occurred 4 weeks before the appearance of histopathological dysplasia, and 8 weeks prior to development of grossly visible tumors.
(15) Proliferative responses to env were seen in 9% of control children compared with 27% of infected children (p less than 0.02).
(16) The relationship between interphase cytogenetics and tumor grade, stage, and proliferative activity was investigated in 27 transitional cell carcinomas of the urinary bladder.
(17) Although T cells exposed to antigen in B-depleted LN of mu sm and irradiated mice gave negligible T proliferative responses in vitro, low but significant levels of primed T helper function were detected in a sensitive T helper assay in vivo.
(18) These results suggest that HGF may act as a proliferative factor during fetal liver growth.
(19) Proliferative and cytollytical activity of lymphocytes was compared in lymphocyte alloimmunization of the spleen and intact thymus.
(20) The high proteolytic activity of BCC demonstrated in this study may be an important factor in the proliferative, invasive and destructive behaviour of this tumour.