(a.) Descending far below the surface; opening or reaching to a great depth; deep.
(a.) Intellectually deep; entering far into subjects; reaching to the bottom of a matter, or of a branch of learning; thorough; as, a profound investigation or treatise; a profound scholar; profound wisdom.
(a.) Characterized by intensity; deeply felt; pervading; overmastering; far-reaching; strongly impressed; as, a profound sleep.
(a.) Bending low, exhibiting or expressing deep humility; lowly; submissive; as, a profound bow.
(n.) The deep; the sea; the ocean.
(n.) An abyss.
(v. t.) To cause to sink deeply; to cause to dive or penetrate far down.
(v. i.) To dive deeply; to penetrate.
Example Sentences:
(1) With profound blockade, the slope of the edrophonium dose-response relationship was significantly flatter (P less than 0.05) than that of neostigmine.
(2) Cadavers have a multitude of possible uses--from the harvesting of organs, to medical education, to automotive safety testing--and yet their actual utilization arouses profound aversion no matter how altruistic and beneficial the motivation.
(3) Our positive experiences with IMACS discussed above should be even more profound and profitable for the larger medical institutions.
(4) This study compares the effects of 60 minutes of ischemic arrest with profound topical hypothermia (10 dogs) on myocardial (1) blood flow and distribution (microspheres), (2) metabolism (oxygen and lactate), (3) water content (wet to dry weights), (4) compliance (intraventricular balloon), and (5) performance (isovolumetric function curves) with 180 minutes of cardiopulmonary bypass with the heart in the beating empty state (seven dogs).
(5) About one out of three profoundly deaf children has an autosomal recessive form of inherited deafness.
(6) This continuing influence of Nazi medicine raises profound questions for the epistemology and morality of medicine.
(7) However six equivocal studies were observed in profoundly jaundiced patients with bilirubin levels above 400 mumol l-1 due to difficulties in differentiating extrahepatic obstruction from severe intrahepatic cholestasis.
(8) After a 2-day incubation with IL-4, expression of IL-2R p55 was markedly induced, but expression of IL2-R p70-75 was profoundly suppressed in a dose-dependent manner.
(9) "For those people who are able to use the laws, the change is profound."
(10) Most striking finding was his difficulty in identifying common objects and colours along with a profound alexia.
(11) This BOA technique was used to test the hearing of 82 profoundly involved handicapped children.
(12) These tools will allow us to manipulate the mammalian immune response in a variety of different ways that will have a profound impact both on our understanding of immunology and on medicine in the future.
(13) Based on the fact that all hibernators, at their regulated minimal body temperature, display a uniform turnover rate, related to body weight, the hypothesis is developed that cold tolerance of mammals is generally limited by a common specific minimal metabolic rate, which larger organisms, because of their lower basal metabolism, already attain in less profound hypothermia.
(14) Insulin-like growth factor II (IGF-II) is present at high levels in fetal and early neonatal rat plasma, and decreases profoundly following birth.
(15) The reduction in level of activity and adverse changes in body composition caused by SCI have profound metabolic consequences that may influence the progression and severity of coronary artery disease.
(16) The case of a 32-year-old man who suffered a blow to his left supraorbital region and eyebrow in an automatic closing door is reported to draw attention to the uncommon but trivial nature of this injury which may result in profound visual loss.
(17) In the paper life-threatening diseases which may be accompanied by profound unconsciousness are explained from the laboratory-chemical point of view.
(18) However pneumonia to PC points to a poor prognosis because they are always associated with a profound deficit or cellular immunity.
(19) Thus, it is possible that the loss of these dendritic cells may contribute to the profound immunological abnormalities seen in AIDS.
(20) They produce a more profound effect on clinical and biochemical aspects of rheumatoid arthritis than do the aspirin-like non steroidals.
Profundity
Definition:
(n.) The quality or state of being profound; depth of place, knowledge, feeling, etc.
Example Sentences:
(1) The substances released by algae in the profundal are taken up by aquatic bacteria which explains the lower release and PER measured.
(2) Thirty patients with 43 ischaemic limbs were treated by profundal revascularization.
(3) PCB and sigma DDT concentrations were greater in the predatory bottom animals than in the herbivores or detritus feeders, and the amounts of chlorinated hydrocarbons were greater in profundal animals than in littoral animals.
(4) The ganglia of the anterodorsal lateral line and profundal-trigeminal nerves are totally separate throughout their rostrocaudal extent.
(5) The constrictor effects of sympathetic nerve activity (SNA) on the profundal femoral, circumflex femoral, saphenous, and popliteal arteries varied among 19 out of 20 sites.
(6) "Contrast that with the 'deep-voiced' man, and its connotations of profundity.
(7) This syndrome, which was first described in 1959, is characterized by mechanical pain in one or both hips and profund osteoporosis occurring shortly before or during the third trimester of pregnancy.
(8) He veered between profundity and giggles, sometimes all in one sentence.
(9) The higher release of algal products of photosynthesis in the photic zone than in the profundal is probably caused by the inhibition of physiological activity of bacteria by antibacterial substances produced by algae.
(10) The mathematical probability of procervical activity (1.0 if all procervical; 0.0 if all profundal), and thus the transport, was 0.59 in eumenorrheic and 0.68 in dysmenorrheic patients, the average for the whole series being 0.65.
(11) "Their words carry a profundity and eloquence that deserves to be heard alongside George Washington or Shakespeare or St Catherine of Siena."
(12) Because of its safety and the profundity of its hypolipidemic action, it is suggested that charcoal may find applicability in the management of azotemic diabetic and nephrotic hyperlipidemia.
(13) Naegleria and Vahlkampfia were the most frequently encountered FLA in littoral sediment and surface water samples whereas Acanthamoeba was most commonly isolated from profundal sediment, especially during late summer.
(14) Populations in profundal sediment underwent dramatic seasonal shifts, apparently in response to the seasonal chemical changes in the hypolimnion.
(15) 1 aorto-profundal and 2 iliaco-femoral bypasses have remaint.
(16) Acanthamoeba was most prevalent in late summer, representing as much as 82% of the FLA in profundal sediment.
(17) Microbial biomass and activity were examined in four different arctic sediments: littoral lake sediment and profundal lake sediment from Toolik Lake, Alaska, thaw pond sediment, and eroding river bank peat.
(18) He looked up to see a lissome figure with gentle brown eyes that held a profundity of experience rarely encountered in someone of her age.
(19) Quantitative estimation of the priority ranges made it possible to determine the profundity of the functional relations between the cerebral structures.
(20) The sainted Richard Dawkins habitually manages to frame the questions involved with his customary profundity – claiming in The God Delusion, for example, that: “When my life is taken out, I want to be under general anaesthetic, as if it were my diseased appendix.” But Pharoah’s story shines light on the nuance and complexity that surrounds the whole question, and the cultural factors that are in danger of pushing the argument somewhere very unpleasant.