(a.) Descending far below the surface; opening or reaching to a great depth; deep.
(a.) Intellectually deep; entering far into subjects; reaching to the bottom of a matter, or of a branch of learning; thorough; as, a profound investigation or treatise; a profound scholar; profound wisdom.
(a.) Characterized by intensity; deeply felt; pervading; overmastering; far-reaching; strongly impressed; as, a profound sleep.
(a.) Bending low, exhibiting or expressing deep humility; lowly; submissive; as, a profound bow.
(n.) The deep; the sea; the ocean.
(n.) An abyss.
(v. t.) To cause to sink deeply; to cause to dive or penetrate far down.
(v. i.) To dive deeply; to penetrate.
Example Sentences:
(1) With profound blockade, the slope of the edrophonium dose-response relationship was significantly flatter (P less than 0.05) than that of neostigmine.
(2) Cadavers have a multitude of possible uses--from the harvesting of organs, to medical education, to automotive safety testing--and yet their actual utilization arouses profound aversion no matter how altruistic and beneficial the motivation.
(3) Our positive experiences with IMACS discussed above should be even more profound and profitable for the larger medical institutions.
(4) This study compares the effects of 60 minutes of ischemic arrest with profound topical hypothermia (10 dogs) on myocardial (1) blood flow and distribution (microspheres), (2) metabolism (oxygen and lactate), (3) water content (wet to dry weights), (4) compliance (intraventricular balloon), and (5) performance (isovolumetric function curves) with 180 minutes of cardiopulmonary bypass with the heart in the beating empty state (seven dogs).
(5) About one out of three profoundly deaf children has an autosomal recessive form of inherited deafness.
(6) This continuing influence of Nazi medicine raises profound questions for the epistemology and morality of medicine.
(7) However six equivocal studies were observed in profoundly jaundiced patients with bilirubin levels above 400 mumol l-1 due to difficulties in differentiating extrahepatic obstruction from severe intrahepatic cholestasis.
(8) After a 2-day incubation with IL-4, expression of IL-2R p55 was markedly induced, but expression of IL2-R p70-75 was profoundly suppressed in a dose-dependent manner.
(9) "For those people who are able to use the laws, the change is profound."
(10) Most striking finding was his difficulty in identifying common objects and colours along with a profound alexia.
(11) This BOA technique was used to test the hearing of 82 profoundly involved handicapped children.
(12) These tools will allow us to manipulate the mammalian immune response in a variety of different ways that will have a profound impact both on our understanding of immunology and on medicine in the future.
(13) Based on the fact that all hibernators, at their regulated minimal body temperature, display a uniform turnover rate, related to body weight, the hypothesis is developed that cold tolerance of mammals is generally limited by a common specific minimal metabolic rate, which larger organisms, because of their lower basal metabolism, already attain in less profound hypothermia.
(14) Insulin-like growth factor II (IGF-II) is present at high levels in fetal and early neonatal rat plasma, and decreases profoundly following birth.
(15) The reduction in level of activity and adverse changes in body composition caused by SCI have profound metabolic consequences that may influence the progression and severity of coronary artery disease.
(16) The case of a 32-year-old man who suffered a blow to his left supraorbital region and eyebrow in an automatic closing door is reported to draw attention to the uncommon but trivial nature of this injury which may result in profound visual loss.
(17) In the paper life-threatening diseases which may be accompanied by profound unconsciousness are explained from the laboratory-chemical point of view.
(18) However pneumonia to PC points to a poor prognosis because they are always associated with a profound deficit or cellular immunity.
(19) Thus, it is possible that the loss of these dendritic cells may contribute to the profound immunological abnormalities seen in AIDS.
(20) They produce a more profound effect on clinical and biochemical aspects of rheumatoid arthritis than do the aspirin-like non steroidals.
Propound
Definition:
(v. t.) To offer for consideration; to exhibit; to propose; as, to propound a question; to propound an argument.
(v. t.) To propose or name as a candidate for admission to communion with a church.
Example Sentences:
(1) A critical review of these regimens quickly reveals that the majority are propounded with considerably more confidence than statistical proof of their efficacy.
(2) This paper, presented as part of a panel on the subject, has propounded the view that the defense is unconscionable, using that aspect of the definition dealing with unreasonableness.
(3) While the classical theory of menstrual reflux easily accounts for the genital locations, other theories, notably metaplasia, have been propounded to explain more remote locations.
(4) We can see from the examples discussed that there are many instances where principles, guidelines, rules or laws propounded for the benefit of one party may restrain autonomy, beneficence and justice done to another.
(5) In 1975 in southern Tamil Nadu, an aged practitioner of Ayurveda conducted for the author's benefit a series of lectures about cancer, in which he propounded his own idiosyncratic theory regarding the nature of this disease.
(6) This conclusion is contrary to that which has been propounded to explain the nonlinear dose curves obtained for specific locus mutations.
(7) Various theories about its pathogenesis have been propounded.
(8) A purely catabolic function of 5'-nucleotidase, as propounded in the literature, seems dubious since high 5'-nucleotidase activity was demonstrated in rapidly proliferating tissue too.
(9) Various theories on the best therapy have been propounded in the literature.
(10) In the light of two case-histories, one of which never published before, and on the basis of the Freudian theory of masochism, an interpretation of the data is propounded.
(11) This phenomenon is interpreted in the framework of an ongoing intergroup interaction among patients and between patients and staff, as conceptualized in the Tavistock Model propounded by Bion.
(12) However already propounded several years earlier by Leonhard, a distinction between bipolar and unipolar affective disorders has first been taken into general consideration during the last quarter of a century.
(13) In my book published in Paris (1986) I propound a new, radically different approach which takes into account Man's whole lifespan, without separating the various ages, and without separating old age from those that precede it.
(14) The pathoanatomic view ascribed to Virchow and propounded by Thomas Szasz has coexisted with the patient-centered or phenomenologic view for millenia.
(15) A clinical and mythological analysis is propounded.
(16) The efficacy of autogenous dermal grafts for carotid artery protection in head and neck surgery has been investigated experimentally and propounded clinically.
(17) The fact that I was originally one half of a duo gave rise to a theory, much propounded in newspaper profiles, that my life has been one desperate effort to compensate for that stillborn brother.
(18) On the basis of the analysis of five original and of 181 previously published observations since 1975: the histological, histogenetic, evolutive and epidemiologic patterns of renal angiomyolipoma are exposed; the symptoms at presentation and the clinical manifestations are analysed; some morbid associations of this affection are considered and, particularly, its particular relationship with the tuberous sclerosis is debated; the diagnosis of these angiomyolipomas is studied with special regard to the role of modern radiologic explorations; finally, is propounded a therapeutic codification, which relies mainly on surgery.
(19) Since the term traumatic pseudolipoma of the buccal mucosa was originally propounded to describe a traumatic herniation of the buccal fat pad, five additional cases have been reported.
(20) The traditional teaching of the subject in the Faculty of Medical Sciences of Rosario National University, Santa Fe, Rosario, Argentina, up to 1974 is subjected to critical analysis, and on this basis the need for the innovation is propounded and the method for applying it proposed.