(a.) Descending far below the surface; opening or reaching to a great depth; deep.
(a.) Intellectually deep; entering far into subjects; reaching to the bottom of a matter, or of a branch of learning; thorough; as, a profound investigation or treatise; a profound scholar; profound wisdom.
(a.) Characterized by intensity; deeply felt; pervading; overmastering; far-reaching; strongly impressed; as, a profound sleep.
(a.) Bending low, exhibiting or expressing deep humility; lowly; submissive; as, a profound bow.
(n.) The deep; the sea; the ocean.
(n.) An abyss.
(v. t.) To cause to sink deeply; to cause to dive or penetrate far down.
(v. i.) To dive deeply; to penetrate.
Example Sentences:
(1) With profound blockade, the slope of the edrophonium dose-response relationship was significantly flatter (P less than 0.05) than that of neostigmine.
(2) Cadavers have a multitude of possible uses--from the harvesting of organs, to medical education, to automotive safety testing--and yet their actual utilization arouses profound aversion no matter how altruistic and beneficial the motivation.
(3) Our positive experiences with IMACS discussed above should be even more profound and profitable for the larger medical institutions.
(4) This study compares the effects of 60 minutes of ischemic arrest with profound topical hypothermia (10 dogs) on myocardial (1) blood flow and distribution (microspheres), (2) metabolism (oxygen and lactate), (3) water content (wet to dry weights), (4) compliance (intraventricular balloon), and (5) performance (isovolumetric function curves) with 180 minutes of cardiopulmonary bypass with the heart in the beating empty state (seven dogs).
(5) About one out of three profoundly deaf children has an autosomal recessive form of inherited deafness.
(6) This continuing influence of Nazi medicine raises profound questions for the epistemology and morality of medicine.
(7) However six equivocal studies were observed in profoundly jaundiced patients with bilirubin levels above 400 mumol l-1 due to difficulties in differentiating extrahepatic obstruction from severe intrahepatic cholestasis.
(8) After a 2-day incubation with IL-4, expression of IL-2R p55 was markedly induced, but expression of IL2-R p70-75 was profoundly suppressed in a dose-dependent manner.
(9) "For those people who are able to use the laws, the change is profound."
(10) Most striking finding was his difficulty in identifying common objects and colours along with a profound alexia.
(11) This BOA technique was used to test the hearing of 82 profoundly involved handicapped children.
(12) These tools will allow us to manipulate the mammalian immune response in a variety of different ways that will have a profound impact both on our understanding of immunology and on medicine in the future.
(13) Based on the fact that all hibernators, at their regulated minimal body temperature, display a uniform turnover rate, related to body weight, the hypothesis is developed that cold tolerance of mammals is generally limited by a common specific minimal metabolic rate, which larger organisms, because of their lower basal metabolism, already attain in less profound hypothermia.
(14) Insulin-like growth factor II (IGF-II) is present at high levels in fetal and early neonatal rat plasma, and decreases profoundly following birth.
(15) The reduction in level of activity and adverse changes in body composition caused by SCI have profound metabolic consequences that may influence the progression and severity of coronary artery disease.
(16) The case of a 32-year-old man who suffered a blow to his left supraorbital region and eyebrow in an automatic closing door is reported to draw attention to the uncommon but trivial nature of this injury which may result in profound visual loss.
(17) In the paper life-threatening diseases which may be accompanied by profound unconsciousness are explained from the laboratory-chemical point of view.
(18) However pneumonia to PC points to a poor prognosis because they are always associated with a profound deficit or cellular immunity.
(19) Thus, it is possible that the loss of these dendritic cells may contribute to the profound immunological abnormalities seen in AIDS.
(20) They produce a more profound effect on clinical and biochemical aspects of rheumatoid arthritis than do the aspirin-like non steroidals.
Sea
Definition:
(n.) One of the larger bodies of salt water, less than an ocean, found on the earth's surface; a body of salt water of second rank, generally forming part of, or connecting with, an ocean or a larger sea; as, the Mediterranean Sea; the Sea of Marmora; the North Sea; the Carribean Sea.
(n.) An inland body of water, esp. if large or if salt or brackish; as, the Caspian Sea; the Sea of Aral; sometimes, a small fresh-water lake; as, the Sea of Galilee.
(n.) The ocean; the whole body of the salt water which covers a large part of the globe.
(n.) The swell of the ocean or other body of water in a high wind; motion of the water's surface; also, a single wave; a billow; as, there was a high sea after the storm; the vessel shipped a sea.
(n.) A great brazen laver in the temple at Jerusalem; -- so called from its size.
(n.) Fig.: Anything resembling the sea in vastness; as, a sea of glory.
Example Sentences:
(1) A full-scale war is unlikely but there is clear concern in Seoul about the more realistic threat of a small-scale attack on the South Korean military or a group of islands near the countries' disputed maritime border in the Yellow Sea.
(2) Blood samples were collected from an antecubital vein at sea level (S1), in a base camp at 1515 m prior to the summit ascent (S2), on the summit at 3285 m after 6.5 hours of climbing (S3), at base camp immediately after the descent (S4), and at sea level following a trail descent from the base camp (S5).
(3) "In a sea of bubblegum-cute popsters, Sistar stand out for their cool and sexy image," says Scobie.
(4) The compromised ice sheet tilts and he sinks into the Arctic Sea on the back of his faltering white Icelandic pony.
(5) This is an edited extract from Across the Seas – Australia’s Response to Refugees: A History by Klaus Neumann, published by Black Inc. Books and on-sale now .
(6) Two years ago, the Intergovernmental Panel on Climate Change declared Egypt's Nile Delta to be among the top three areas on the planet most vulnerable to a rise in sea levels, and even the most optimistic predictions of global temperature increase will still displace millions of Egyptians from one of the most densely populated regions on earth.
(7) It is shown that the combined effects of altitude and wind assistance yielded an increment in the length of the jump of about 31 cm, compared to a corresponding jump at sea level under still air conditions.
(8) Two similar calici agents, San Miguel sea lion virus (SMSV) and vesicular exanthema of swine virus (VESV) are susceptible to the virucidal activity of disinfectants of differing formulation.
(9) The sea ice usually then begins to freeze again over the winter.
(10) The sequential resonance assignment of the 1H NMR spectrum of the antihypertensive and antiviral protein BDS-I from the sea anemone Anemonia sulcata is presented.
(11) In the present work by the method of molecular DNA hybridization there was shown a low degree of affinity of the standard museum strains of cholera vibrios to the respresentatives of the sea species V. parahaemolyticus and V. alginolyticus, and also halophilic vibrios identified earlier on the basis of phenotypical characteristics of the nucleotide DNA composition as Marinovibrio.
(12) A guide, £44pp, is compulsory ( rscn.org.jo ) 2 Discover the Nuweiba coast: Red Sea, Egypt Beach, Nuweiba, Sinai, Egypt.
(13) In Tokyo, the US president warned China against forcibly pressing its maritime claims, following Beijing's unilateral declaration last autumn of an air exclusion zone over Japanese-controlled islands in the East China Sea.
(14) The highest rates were observed where the inhabitants' activities were related to the sea.
(15) CyIIIa.CAT) expression simultaneously in embryos bearing excess competitor regulatory DNA, we developed, and here describe, a new procedure for generating transgenic sea urchin embryos in which all of the cells in many embryos, and most in others, bear the exogenous DNA.
(16) All have territorial disputes with Beijing over the South China Sea , a route for about $4.5tn (£3.4tn) in trade that the US is concerned China wants to fully control.
(17) This time, as a journalist covering the event, I was arrested on the high seas, briefly imprisoned and interrogated on Mururoa itself while the tests continued.
(18) The cytolytic activity of peritoneal SEA reactive effector cells was confined to the TCR alpha beta+ CD4- CD8+ CD45RC- cell population.
(19) A light rain pattered the rooftops of Los Mochis in Friday’s pre-dawn darkness, the town silent and still as the Sea of Cortez lapped its shore.
(20) With grievous amazement, never self-pitying but sometimes bordering on a sort of numbed wonderment, Levi records the day-to-day personal and social history of the camp, noting not only the fine gradations of his own descent, but the capacity of some prisoners to cut a deal and strike a bargain, while others, destined by their age or character for the gas ovens, follow "the slope down to the bottom, like streams that run down to the sea".