(a.) Descending far below the surface; opening or reaching to a great depth; deep.
(a.) Intellectually deep; entering far into subjects; reaching to the bottom of a matter, or of a branch of learning; thorough; as, a profound investigation or treatise; a profound scholar; profound wisdom.
(a.) Characterized by intensity; deeply felt; pervading; overmastering; far-reaching; strongly impressed; as, a profound sleep.
(a.) Bending low, exhibiting or expressing deep humility; lowly; submissive; as, a profound bow.
(n.) The deep; the sea; the ocean.
(n.) An abyss.
(v. t.) To cause to sink deeply; to cause to dive or penetrate far down.
(v. i.) To dive deeply; to penetrate.
Example Sentences:
(1) With profound blockade, the slope of the edrophonium dose-response relationship was significantly flatter (P less than 0.05) than that of neostigmine.
(2) Cadavers have a multitude of possible uses--from the harvesting of organs, to medical education, to automotive safety testing--and yet their actual utilization arouses profound aversion no matter how altruistic and beneficial the motivation.
(3) Our positive experiences with IMACS discussed above should be even more profound and profitable for the larger medical institutions.
(4) This study compares the effects of 60 minutes of ischemic arrest with profound topical hypothermia (10 dogs) on myocardial (1) blood flow and distribution (microspheres), (2) metabolism (oxygen and lactate), (3) water content (wet to dry weights), (4) compliance (intraventricular balloon), and (5) performance (isovolumetric function curves) with 180 minutes of cardiopulmonary bypass with the heart in the beating empty state (seven dogs).
(5) About one out of three profoundly deaf children has an autosomal recessive form of inherited deafness.
(6) This continuing influence of Nazi medicine raises profound questions for the epistemology and morality of medicine.
(7) However six equivocal studies were observed in profoundly jaundiced patients with bilirubin levels above 400 mumol l-1 due to difficulties in differentiating extrahepatic obstruction from severe intrahepatic cholestasis.
(8) After a 2-day incubation with IL-4, expression of IL-2R p55 was markedly induced, but expression of IL2-R p70-75 was profoundly suppressed in a dose-dependent manner.
(9) "For those people who are able to use the laws, the change is profound."
(10) Most striking finding was his difficulty in identifying common objects and colours along with a profound alexia.
(11) This BOA technique was used to test the hearing of 82 profoundly involved handicapped children.
(12) These tools will allow us to manipulate the mammalian immune response in a variety of different ways that will have a profound impact both on our understanding of immunology and on medicine in the future.
(13) Based on the fact that all hibernators, at their regulated minimal body temperature, display a uniform turnover rate, related to body weight, the hypothesis is developed that cold tolerance of mammals is generally limited by a common specific minimal metabolic rate, which larger organisms, because of their lower basal metabolism, already attain in less profound hypothermia.
(14) Insulin-like growth factor II (IGF-II) is present at high levels in fetal and early neonatal rat plasma, and decreases profoundly following birth.
(15) The reduction in level of activity and adverse changes in body composition caused by SCI have profound metabolic consequences that may influence the progression and severity of coronary artery disease.
(16) The case of a 32-year-old man who suffered a blow to his left supraorbital region and eyebrow in an automatic closing door is reported to draw attention to the uncommon but trivial nature of this injury which may result in profound visual loss.
(17) In the paper life-threatening diseases which may be accompanied by profound unconsciousness are explained from the laboratory-chemical point of view.
(18) However pneumonia to PC points to a poor prognosis because they are always associated with a profound deficit or cellular immunity.
(19) Thus, it is possible that the loss of these dendritic cells may contribute to the profound immunological abnormalities seen in AIDS.
(20) They produce a more profound effect on clinical and biochemical aspects of rheumatoid arthritis than do the aspirin-like non steroidals.
Shallow
Definition:
(superl.) Not deep; having little depth; shoal.
(superl.) Not deep in tone.
(superl.) Not intellectually deep; not profound; not penetrating deeply; simple; not wise or knowing; ignorant; superficial; as, a shallow mind; shallow learning.
(n.) A place in a body of water where the water is not deep; a shoal; a flat; a shelf.
(n.) The rudd.
(v. t.) To make shallow.
(v. i.) To become shallow, as water.
Example Sentences:
(1) Intestinal glands are not observed until 8.5cm, and are shallow in depth even in the adult.
(2) Terrorist groups need to be tackled at root, interdicting flows of weapons and finance, exposing the shallowness of their claims, channelling their followers into democratic politics.
(3) Those with shallow roots are least likely to mourn change.
(4) In comparison gradients of transcript levels are more shallow in either lytically or persistently infected cultured cells, where the transcripts of the fifth MV gene are only about five times less abundant than those of the first.
(5) With commonly used experimental procedures, it is difficult to know whether a shallow psychometric function slope is a true reflection of the sensory process, or is a result of "averaging" a highly variable underlying function.
(6) The lesions varied in length from 0.5 to 2 cm and were very shallow, generally 1 mm deep.
(7) Further purification of the fraction by equilibrium centrifugation on shallow sucrose gradients reduces further the contaminating activities and results in a PA distribution that closely parallels the distribution of the membrane enzyme, 5'-nucleotidase.
(8) A case of acute angle-closure glaucoma precipitated by oculomotor nerve palsy in a patient with shallow anterior chambers is reported.
(9) From the shallow pool of talent to the lack of a definable playing style and questions over whether they can handle the step up from qualification to tournament football, this is now England.
(10) In Experiment 1, it was found that deviations of observed recognition failure from predictions of the Tulving-Wiseman function (Tulving & Wiseman, 1975) were produced by shallow, nonsemantic encoding.
(11) Recordings from single neurons in the primary somatosensory cortex of the monkey during force regulation between the fingers showed following characteristics: the existence of classes of discharge patterns similar to those in motor cortex, but with differences in their distribution, a late onset of activity changes in relation to force increase and a linear relation to force, but with shallow mean rate-force slope.
(12) Families picnic between games of crazy golf or volleyball, bathers brave the shallows, children splash in the saltwater lido.
(13) Angiotensin II induced a weak secretion of both adrenaline and noradrenaline, with a threshold of 10-100 pM and a shallow concentration-dependence up to 10 microM.
(14) The threshold of instantaneous change of stage 2 to shallower stages due to the sound of a passing truck was at the peak level at less than 55 dB (A), and that of stage REM to other stages at 55 to 60 dB (A).
(15) Maybe this is symptomatic of how the possibilities of social media have just made our friendships shallower, an economy of “likes” and thoughtless “adds”.
(16) In addition, it was a shallow event with a source that was only 11km below ground.
(17) Some of the stomata overlie a deep pit; others overlie a shallower pit in which the surface of another cell can be seen beneath the opening.
(18) Initially each primordium forms a shallow depression in the ectodermal surface.
(19) Under the scanning electron microscope, the clear dentine tubules in the resorption lacuna, the shallow, unclear resorption lacuna with deposition of the hard tissue and the various steps between them were observed.
(20) We found shallow serpiginous, longitudinal ulcerations in the descending colon at the first examination of a 17-year-old female patient with Crohn's disease.