(a.) Descending far below the surface; opening or reaching to a great depth; deep.
(a.) Intellectually deep; entering far into subjects; reaching to the bottom of a matter, or of a branch of learning; thorough; as, a profound investigation or treatise; a profound scholar; profound wisdom.
(a.) Characterized by intensity; deeply felt; pervading; overmastering; far-reaching; strongly impressed; as, a profound sleep.
(a.) Bending low, exhibiting or expressing deep humility; lowly; submissive; as, a profound bow.
(n.) The deep; the sea; the ocean.
(n.) An abyss.
(v. t.) To cause to sink deeply; to cause to dive or penetrate far down.
(v. i.) To dive deeply; to penetrate.
Example Sentences:
(1) With profound blockade, the slope of the edrophonium dose-response relationship was significantly flatter (P less than 0.05) than that of neostigmine.
(2) Cadavers have a multitude of possible uses--from the harvesting of organs, to medical education, to automotive safety testing--and yet their actual utilization arouses profound aversion no matter how altruistic and beneficial the motivation.
(3) Our positive experiences with IMACS discussed above should be even more profound and profitable for the larger medical institutions.
(4) This study compares the effects of 60 minutes of ischemic arrest with profound topical hypothermia (10 dogs) on myocardial (1) blood flow and distribution (microspheres), (2) metabolism (oxygen and lactate), (3) water content (wet to dry weights), (4) compliance (intraventricular balloon), and (5) performance (isovolumetric function curves) with 180 minutes of cardiopulmonary bypass with the heart in the beating empty state (seven dogs).
(5) About one out of three profoundly deaf children has an autosomal recessive form of inherited deafness.
(6) This continuing influence of Nazi medicine raises profound questions for the epistemology and morality of medicine.
(7) However six equivocal studies were observed in profoundly jaundiced patients with bilirubin levels above 400 mumol l-1 due to difficulties in differentiating extrahepatic obstruction from severe intrahepatic cholestasis.
(8) After a 2-day incubation with IL-4, expression of IL-2R p55 was markedly induced, but expression of IL2-R p70-75 was profoundly suppressed in a dose-dependent manner.
(9) "For those people who are able to use the laws, the change is profound."
(10) Most striking finding was his difficulty in identifying common objects and colours along with a profound alexia.
(11) This BOA technique was used to test the hearing of 82 profoundly involved handicapped children.
(12) These tools will allow us to manipulate the mammalian immune response in a variety of different ways that will have a profound impact both on our understanding of immunology and on medicine in the future.
(13) Based on the fact that all hibernators, at their regulated minimal body temperature, display a uniform turnover rate, related to body weight, the hypothesis is developed that cold tolerance of mammals is generally limited by a common specific minimal metabolic rate, which larger organisms, because of their lower basal metabolism, already attain in less profound hypothermia.
(14) Insulin-like growth factor II (IGF-II) is present at high levels in fetal and early neonatal rat plasma, and decreases profoundly following birth.
(15) The reduction in level of activity and adverse changes in body composition caused by SCI have profound metabolic consequences that may influence the progression and severity of coronary artery disease.
(16) The case of a 32-year-old man who suffered a blow to his left supraorbital region and eyebrow in an automatic closing door is reported to draw attention to the uncommon but trivial nature of this injury which may result in profound visual loss.
(17) In the paper life-threatening diseases which may be accompanied by profound unconsciousness are explained from the laboratory-chemical point of view.
(18) However pneumonia to PC points to a poor prognosis because they are always associated with a profound deficit or cellular immunity.
(19) Thus, it is possible that the loss of these dendritic cells may contribute to the profound immunological abnormalities seen in AIDS.
(20) They produce a more profound effect on clinical and biochemical aspects of rheumatoid arthritis than do the aspirin-like non steroidals.
Strong
Definition:
(superl.) Having active physical power, or great physical power to act; having a power of exerting great bodily force; vigorous.
(superl.) Having passive physical power; having ability to bear or endure; firm; hale; sound; robust; as, a strong constitution; strong health.
(superl.) Solid; tough; not easily broken or injured; able to withstand violence; able to sustain attacks; not easily subdued or taken; as, a strong beam; a strong rock; a strong fortress or town.
(superl.) Having great military or naval force; powerful; as, a strong army or fleet; a nation strong at sea.
(superl.) Having great wealth, means, or resources; as, a strong house, or company of merchants.
(superl.) Reaching a certain degree or limit in respect to strength or numbers; as, an army ten thousand strong.
(superl.) Moving with rapidity or force; violent; forcible; impetuous; as, a strong current of water or wind; the wind was strong from the northeast; a strong tide.
(superl.) Adapted to make a deep or effectual impression on the mind or imagination; striking or superior of the kind; powerful; forcible; cogent; as, a strong argument; strong reasons; strong evidence; a strong example; strong language.
(superl.) Ardent; eager; zealous; earnestly engaged; as, a strong partisan; a strong Whig or Tory.
(superl.) Having virtues of great efficacy; or, having a particular quality in a great degree; as, a strong powder or tincture; a strong decoction; strong tea or coffee.
(superl.) Full of spirit; containing a large proportion of alcohol; intoxicating; as, strong liquors.
(superl.) Affecting any sense powerfully; as, strong light, colors, etc.; a strong flavor of onions; a strong scent.
(superl.) Solid; nourishing; as, strong meat.
(superl.) Well established; firm; not easily overthrown or altered; as, a strong custom; a strong belief.
(superl.) Violent; vehement; earnest; ardent.
(superl.) Having great force, vigor, power, or the like, as the mind, intellect, or any faculty; as, a man of a strong mind, memory, judgment, or imagination.
(superl.) Tending to higher prices; rising; as, a strong market.
(superl.) Pertaining to, or designating, a verb which forms its preterit (imperfect) by a variation in the root vowel, and the past participle (usually) by the addition of -en (with or without a change of the root vowel); as in the verbs strive, strove, striven; break, broke, broken; drink, drank, drunk. Opposed to weak, or regular. See Weak.
(superl.) Applied to forms in Anglo-Saxon, etc., which retain the old declensional endings. In the Teutonic languages the vowel stems have held the original endings most firmly, and are called strong; the stems in -n are called weak other constant stems conform, or are irregular.
Example Sentences:
(1) For some time now, public opinion polls have revealed Americans' strong preference to live in comparatively small cities, towns, and rural areas rather than in large cities.
(2) Perinatal mortality is strongly associated with obstetrical factors, respiratory distress syndrome, and prematurity.
(3) We conclude that the SHBG concentration strongly affects this estimation.
(4) When the data correlating DHT with protein synthesis using both labelling techniques were combined, the curves were parallel and a strong correlation was noted between DHT and protein synthesis over a wide range of values (P less than 0.001).
(5) A strong block to the elongation of nascent RNA transcripts by RNA polymerase II occurs in the 5' part of the mammalian c-fos proto-oncogene.
(6) Importantly, these characteristics were strong predictors of subsequent mortality.
(7) These clones, designated as TcHMC-2, showed strong cytotoxicity against both HMC-2 and K562 cells.
(8) Results demonstrate that the development of biliary strictures is strongly associated with the duration of cold ischemic storage of allografts in both Euro-Collins solution and University of Wisconsin solution.
(9) "There is … a risk that the political, trade, and gas frictions with Russia could lead to strong deterioration in economic relations between the two countries, with a significant drop in Ukraine's exports to and imports from Russia.
(10) Univariate and multivariate analyses indicated previous LBP or back pain in another location of the spine were strongly associated with LBP during the study year.
(11) Environment groups Environment groups that have strongly backed low-carbon power have barely wavered in their opposition to nuclear in the last decade, although their arguments now are now much about the cost than the danger it might pose.
(12) Although the productions of deoxycortisol and androstenedione from 17 alpha-hydroxyprogesterone were strongly inhibited by progesterone, androstenedione formation from progesterone was not inhibited by a high concentration of progesterone.
(13) Simple cells that are nearly equally dominated by each eye always exhibit strong phase-specific interaction.
(14) The activity is strongly inhibited by SH-blocking reagents (e.g.
(15) Nice (the National Institute for Health and Clinical Excellence) has also published new guidance on good patient experience that provides a strong framework on which to build good engagement practice.
(16) In 0.17 M Na+(aq), tRNA(Phe) exists in its native conformation and the number of strong binding sites (Ka greater than or equal to 10(4)) was estimated to be 3-4 by titration experiments, in agreement with X-ray structural data for crystalline tRNA(Phe) (Jack et al., 1977).
(17) The remaining 33 sera (13.3 per cent) were classified as low, moderate or strong positives.
(18) This study provides strong and unexpected evidence that one admission to hospital of more than a week's duration or repeated admissions before the age of five years (in particular between six months and four years) are associated with an increased risk of behaviour disturbance and poor reading in adolescence.
(19) The accumulated evidence would strongly favor an affirmative answer.
(20) Incubation of membrane with DL-Hcys alone (5 X 10(-5) M), the combination of both Ad (5 X 10(-5)) and DL-Hcys (5 X 10(-5)), or S-adenosyl-L-homocysteine (SAH) (1 X 10(-6)) strongly decreased the methyl ester formation.