(a.) Descending far below the surface; opening or reaching to a great depth; deep.
(a.) Intellectually deep; entering far into subjects; reaching to the bottom of a matter, or of a branch of learning; thorough; as, a profound investigation or treatise; a profound scholar; profound wisdom.
(a.) Characterized by intensity; deeply felt; pervading; overmastering; far-reaching; strongly impressed; as, a profound sleep.
(a.) Bending low, exhibiting or expressing deep humility; lowly; submissive; as, a profound bow.
(n.) The deep; the sea; the ocean.
(n.) An abyss.
(v. t.) To cause to sink deeply; to cause to dive or penetrate far down.
(v. i.) To dive deeply; to penetrate.
Example Sentences:
(1) With profound blockade, the slope of the edrophonium dose-response relationship was significantly flatter (P less than 0.05) than that of neostigmine.
(2) Cadavers have a multitude of possible uses--from the harvesting of organs, to medical education, to automotive safety testing--and yet their actual utilization arouses profound aversion no matter how altruistic and beneficial the motivation.
(3) Our positive experiences with IMACS discussed above should be even more profound and profitable for the larger medical institutions.
(4) This study compares the effects of 60 minutes of ischemic arrest with profound topical hypothermia (10 dogs) on myocardial (1) blood flow and distribution (microspheres), (2) metabolism (oxygen and lactate), (3) water content (wet to dry weights), (4) compliance (intraventricular balloon), and (5) performance (isovolumetric function curves) with 180 minutes of cardiopulmonary bypass with the heart in the beating empty state (seven dogs).
(5) About one out of three profoundly deaf children has an autosomal recessive form of inherited deafness.
(6) This continuing influence of Nazi medicine raises profound questions for the epistemology and morality of medicine.
(7) However six equivocal studies were observed in profoundly jaundiced patients with bilirubin levels above 400 mumol l-1 due to difficulties in differentiating extrahepatic obstruction from severe intrahepatic cholestasis.
(8) After a 2-day incubation with IL-4, expression of IL-2R p55 was markedly induced, but expression of IL2-R p70-75 was profoundly suppressed in a dose-dependent manner.
(9) "For those people who are able to use the laws, the change is profound."
(10) Most striking finding was his difficulty in identifying common objects and colours along with a profound alexia.
(11) This BOA technique was used to test the hearing of 82 profoundly involved handicapped children.
(12) These tools will allow us to manipulate the mammalian immune response in a variety of different ways that will have a profound impact both on our understanding of immunology and on medicine in the future.
(13) Based on the fact that all hibernators, at their regulated minimal body temperature, display a uniform turnover rate, related to body weight, the hypothesis is developed that cold tolerance of mammals is generally limited by a common specific minimal metabolic rate, which larger organisms, because of their lower basal metabolism, already attain in less profound hypothermia.
(14) Insulin-like growth factor II (IGF-II) is present at high levels in fetal and early neonatal rat plasma, and decreases profoundly following birth.
(15) The reduction in level of activity and adverse changes in body composition caused by SCI have profound metabolic consequences that may influence the progression and severity of coronary artery disease.
(16) The case of a 32-year-old man who suffered a blow to his left supraorbital region and eyebrow in an automatic closing door is reported to draw attention to the uncommon but trivial nature of this injury which may result in profound visual loss.
(17) In the paper life-threatening diseases which may be accompanied by profound unconsciousness are explained from the laboratory-chemical point of view.
(18) However pneumonia to PC points to a poor prognosis because they are always associated with a profound deficit or cellular immunity.
(19) Thus, it is possible that the loss of these dendritic cells may contribute to the profound immunological abnormalities seen in AIDS.
(20) They produce a more profound effect on clinical and biochemical aspects of rheumatoid arthritis than do the aspirin-like non steroidals.
Treatise
Definition:
(n.) A written composition on a particular subject, in which its principles are discussed or explained; a tract.
(n.) Story; discourse.
Example Sentences:
(1) In tracts and treatises they furiously debated such issues as the nature of man, the powers of God, and the true path to salvation.
(2) It is not a theological treatise.” Furthermore, the writer meant that as praise.
(3) Coming off an honorary Oscar win at last month’s Governors Awards , Lee has delivered one of his most daring and accomplished films to date with Chi-Raq, which transplants the Greek play Lysistrata to modern-day Chicago, to offer a passionate treatise on the gun epidemic that has crippled America.
(4) "The text in itself is probably not a landmark work of Islamic jurisprudence, but it is important because it adds to … a corpus of treatises by former militants challenging al-Qaida on theological grounds," Thomas Hegghammer of Harvard University said on the Jihadica website.
(5) Squeaky-clean Leona Lewis has covered Trent Reznor's hara-kiri-themed treatise Hurt, Beyoncé pre-empted Ke$ha on last year's Rather Die Young, and the Lynchian pretend-we're-dead poise of Lana "Born To Die" Del Rey couldn't be more cadaver chic if she started shaking with rigor mortis, maggots spilling from her eyeballs.
(6) He studied Hippocrates' Airs, Waters and Places, which deals with environmental factors, and the treatise On Regimen especially thoroughly.
(7) During his stay in Berlin for many years Bilguer wrote a number of treatises, in which he expressed his opinion to many medical scientific problems and again to questions of an improved treatment of patients.
(8) Described in an excellent clinical treatise some 8 decades before the advent of radiographs, this fracture of the distal radius continues to pose a source of some disability to large numbers of patients.
(9) The writer Jon Savage is the author of the punk rock history England's Dreaming, and the epic cultural treatise Teenage, recently turned into a feature-length documentary .
(10) His pervasive influence within the field of philanthropy stems more than anything from his treatise on 'wealth' , known as 'The Gospel of Wealth' , where he concludes: "the problem of our age is the proper administration of wealth, so that the ties of brotherhood may still bind together the rich and the poor in harmonious relationship."
(11) In 1627, William Harvey was writing notes for a treatise on the movement of animals, De motu locali animalium, which in the event he neither published nor completed.
(12) Resuming his treatise the author confirms that not yet all sources are used to solve the problems regarded.
(13) Rameau reminded his readers that mathematics is as important in music as it is in astronomy, and saw no conflict between the charts and formulae that fill his treatise and his ravishing operas and instrumental music.
(14) In this part of the treatise is accentuated above all the situation of the forties of our century, in which the processes of academic graduation more than ever before could become a political fact.
(15) The third part of a treatise concerning a viatorium medico-historicum which deals with the region of Saxony-Anhalt leads through the areas of the Harz mountains and their piedmont.
(16) 20, 934-940] pathway for the formation of triacylglycerols when compared with other oil-rich plant species that have been studied [Stymne & Stobart (1987) The Biochemistry of Plants: a Comprehensive Treatise (Stumpf, P.K., ed.
(17) Friedrich Arnold's neuroanatomical treatise Icones nervorum capitis published in its first edition in Heidelberg 1834 ranks scientifically and iconographically among the most brilliant works of 19th century anatomical literature.
(18) Some implications of this treatise for modern psychiatry are discussed.
(19) During these years in Italy, Twombly's output sometimes reflected developments in the rest of the world: for example, as minimalist artists were creating a stir in America and Europe , in the late 1960s Twombly executed six monochrome canvases, the Treatise on the Veil, which are completely blank apart from measurements written in crayon over the grey paint.
(20) In her seminal treatise Man Made Language , the feminist theorist Dale Spender makes the argument that language is a system that embodies sexual inequality.