(a.) Descending far below the surface; opening or reaching to a great depth; deep.
(a.) Intellectually deep; entering far into subjects; reaching to the bottom of a matter, or of a branch of learning; thorough; as, a profound investigation or treatise; a profound scholar; profound wisdom.
(a.) Characterized by intensity; deeply felt; pervading; overmastering; far-reaching; strongly impressed; as, a profound sleep.
(a.) Bending low, exhibiting or expressing deep humility; lowly; submissive; as, a profound bow.
(n.) The deep; the sea; the ocean.
(n.) An abyss.
(v. t.) To cause to sink deeply; to cause to dive or penetrate far down.
(v. i.) To dive deeply; to penetrate.
Example Sentences:
(1) With profound blockade, the slope of the edrophonium dose-response relationship was significantly flatter (P less than 0.05) than that of neostigmine.
(2) Cadavers have a multitude of possible uses--from the harvesting of organs, to medical education, to automotive safety testing--and yet their actual utilization arouses profound aversion no matter how altruistic and beneficial the motivation.
(3) Our positive experiences with IMACS discussed above should be even more profound and profitable for the larger medical institutions.
(4) This study compares the effects of 60 minutes of ischemic arrest with profound topical hypothermia (10 dogs) on myocardial (1) blood flow and distribution (microspheres), (2) metabolism (oxygen and lactate), (3) water content (wet to dry weights), (4) compliance (intraventricular balloon), and (5) performance (isovolumetric function curves) with 180 minutes of cardiopulmonary bypass with the heart in the beating empty state (seven dogs).
(5) About one out of three profoundly deaf children has an autosomal recessive form of inherited deafness.
(6) This continuing influence of Nazi medicine raises profound questions for the epistemology and morality of medicine.
(7) However six equivocal studies were observed in profoundly jaundiced patients with bilirubin levels above 400 mumol l-1 due to difficulties in differentiating extrahepatic obstruction from severe intrahepatic cholestasis.
(8) After a 2-day incubation with IL-4, expression of IL-2R p55 was markedly induced, but expression of IL2-R p70-75 was profoundly suppressed in a dose-dependent manner.
(9) "For those people who are able to use the laws, the change is profound."
(10) Most striking finding was his difficulty in identifying common objects and colours along with a profound alexia.
(11) This BOA technique was used to test the hearing of 82 profoundly involved handicapped children.
(12) These tools will allow us to manipulate the mammalian immune response in a variety of different ways that will have a profound impact both on our understanding of immunology and on medicine in the future.
(13) Based on the fact that all hibernators, at their regulated minimal body temperature, display a uniform turnover rate, related to body weight, the hypothesis is developed that cold tolerance of mammals is generally limited by a common specific minimal metabolic rate, which larger organisms, because of their lower basal metabolism, already attain in less profound hypothermia.
(14) Insulin-like growth factor II (IGF-II) is present at high levels in fetal and early neonatal rat plasma, and decreases profoundly following birth.
(15) The reduction in level of activity and adverse changes in body composition caused by SCI have profound metabolic consequences that may influence the progression and severity of coronary artery disease.
(16) The case of a 32-year-old man who suffered a blow to his left supraorbital region and eyebrow in an automatic closing door is reported to draw attention to the uncommon but trivial nature of this injury which may result in profound visual loss.
(17) In the paper life-threatening diseases which may be accompanied by profound unconsciousness are explained from the laboratory-chemical point of view.
(18) However pneumonia to PC points to a poor prognosis because they are always associated with a profound deficit or cellular immunity.
(19) Thus, it is possible that the loss of these dendritic cells may contribute to the profound immunological abnormalities seen in AIDS.
(20) They produce a more profound effect on clinical and biochemical aspects of rheumatoid arthritis than do the aspirin-like non steroidals.
Unqualified
Definition:
Example Sentences:
(1) That means scrapping David Cameron’s unqualified teacher policy, which has produced a 16% increase in the number of unqualified teachers in our schools.
(2) The palace and the politicians expect a smooth succession to the reign of Charles III, even though he is a man who has spent his life demonstrating how woefully unqualified he is to be a constitutional king.
(3) Former acting director of the CIA, Michael Morell, also weighed in for Clinton in a New York Times opinion piece on Friday, declaring: “Donald J Trump is not only unqualified for the job, but he may well pose a threat to our national security.” Republicans stumbling from the wreckage of a terrible week are worrying about how to contain the damage further down the ballot paper in November as people running for seats in Congress and at state level risk being swept away.
(4) The only unqualified support appears to come from David Cameron and Mr Osborne, and from French president François Hollande who confirmed at his meeting with the PM last week that he wanted it to go ahead.
(5) Its submissions to the consultation, which it forced the MoJ to rerun, states: “There will certainly be plenty of redundancies among qualified solicitors … Given the rates of pay under the new scheme, firms will not be recruiting qualified solicitors but unqualified paralegals.” Nicola Hill, president of the LCCSA, said: “We’re seeing the effect of a policy which puts the cost of justice above its value.
(6) How dare this unqualified mother of three challenge RGCB orthodoxy or attack the hypocrisy of those who condemned viable neighbourhoods as slums in order to build their own golden city from which anyone with choice escaped?
(7) But the institutions suffer from curricula being abandoned due to funding cuts, unqualified – but party-loyal – lecturers, and shoddily built institutions.
(8) On Wednesday, Seth Klarman, a billionaire hedge fund manager and sometime Republican donor, said he would work to get Hillary Clinton elected, condemning Trump’s “shockingly unacceptable” remarks and calling the candidate “completely unqualified for the highest office in the land”.
(9) But freedom of movement has never been an unqualified right, and we now need to allow it to operate on a more sustainable basis in the light of the experience of recent years.
(10) The issues surrounding skill mix are often highly contentious and, not surprisingly, various interest groups either welcome or reject attempts to examine the different combinations of staff, qualified and unqualified, experienced and inexperienced, in relation to costs, outcomes and quality of nursing care.
(11) There are only 14,800 unqualified teachers in schools.
(12) The authors review the literature cited to support this hypothesis and demonstrate that its unqualified acceptance is unfounded.
(13) In the pattern of factors predisposing to newly diagnosed cases of the disease, unsatisfactory housing and living conditions as well as unqualified physical labour performed under unfavourable production and extreme climatic conditions, which are often combined with hazardous habits and concomitant diseases, are becoming more common.
(14) There are clear majorities against unqualified teaching, especially emphatic among Labour voters (68%) and even more particularly Ukip supporters (73%).
(15) Unqualified NIs and older NIs revealed more features of technical nursing and outer teaching than other teachers.
(16) The treasurer, Joe Hockey, who is expected to lose his portfolio if Abbott loses the prime ministership, told reporters Abbott had his “unqualified support”.
(17) Though the results cannot yet be satisfactorily interpreted, they suggest possible reasons for previous conflicting results and show that it is impossible to make the unqualified statement that transport of glycylsarcosine is 'Na+-dependent'.
(18) Thankfully, there is no sign so far of another Oswald Mosley, and the British National party performed poorly in the election, but Gray detects some of the hallmarks of populism – "a diffuse sense of grievance directed at the political class" and "an indeterminate, unlimited hope" – in the 2008 election of the unqualified Boris Johnson as mayor of London, in the carelessly vengeful mood of many voters after the MPs' expenses scandal, and in the three-week wonder of Cleggmania.
(19) This discussion of contraception, pregnancy, and childbirth covers the following: accepting and discharging patients; legal duty of care; contract law; consent; records; time limit; criminal law; sanctions; children under 16; contraception; failed sterilization, vasectomy, and abortion; abortions; pregnancy; delivery; postnatal care; birth at home; and unqualified persons.
(20) These include the appointment of unqualified teachers and inadequate levels of supervision, because local education authorities have little role in monitoring schools.