(a.) Descending far below the surface; opening or reaching to a great depth; deep.
(a.) Intellectually deep; entering far into subjects; reaching to the bottom of a matter, or of a branch of learning; thorough; as, a profound investigation or treatise; a profound scholar; profound wisdom.
(a.) Characterized by intensity; deeply felt; pervading; overmastering; far-reaching; strongly impressed; as, a profound sleep.
(a.) Bending low, exhibiting or expressing deep humility; lowly; submissive; as, a profound bow.
(n.) The deep; the sea; the ocean.
(n.) An abyss.
(v. t.) To cause to sink deeply; to cause to dive or penetrate far down.
(v. i.) To dive deeply; to penetrate.
Example Sentences:
(1) With profound blockade, the slope of the edrophonium dose-response relationship was significantly flatter (P less than 0.05) than that of neostigmine.
(2) Cadavers have a multitude of possible uses--from the harvesting of organs, to medical education, to automotive safety testing--and yet their actual utilization arouses profound aversion no matter how altruistic and beneficial the motivation.
(3) Our positive experiences with IMACS discussed above should be even more profound and profitable for the larger medical institutions.
(4) This study compares the effects of 60 minutes of ischemic arrest with profound topical hypothermia (10 dogs) on myocardial (1) blood flow and distribution (microspheres), (2) metabolism (oxygen and lactate), (3) water content (wet to dry weights), (4) compliance (intraventricular balloon), and (5) performance (isovolumetric function curves) with 180 minutes of cardiopulmonary bypass with the heart in the beating empty state (seven dogs).
(5) About one out of three profoundly deaf children has an autosomal recessive form of inherited deafness.
(6) This continuing influence of Nazi medicine raises profound questions for the epistemology and morality of medicine.
(7) However six equivocal studies were observed in profoundly jaundiced patients with bilirubin levels above 400 mumol l-1 due to difficulties in differentiating extrahepatic obstruction from severe intrahepatic cholestasis.
(8) After a 2-day incubation with IL-4, expression of IL-2R p55 was markedly induced, but expression of IL2-R p70-75 was profoundly suppressed in a dose-dependent manner.
(9) "For those people who are able to use the laws, the change is profound."
(10) Most striking finding was his difficulty in identifying common objects and colours along with a profound alexia.
(11) This BOA technique was used to test the hearing of 82 profoundly involved handicapped children.
(12) These tools will allow us to manipulate the mammalian immune response in a variety of different ways that will have a profound impact both on our understanding of immunology and on medicine in the future.
(13) Based on the fact that all hibernators, at their regulated minimal body temperature, display a uniform turnover rate, related to body weight, the hypothesis is developed that cold tolerance of mammals is generally limited by a common specific minimal metabolic rate, which larger organisms, because of their lower basal metabolism, already attain in less profound hypothermia.
(14) Insulin-like growth factor II (IGF-II) is present at high levels in fetal and early neonatal rat plasma, and decreases profoundly following birth.
(15) The reduction in level of activity and adverse changes in body composition caused by SCI have profound metabolic consequences that may influence the progression and severity of coronary artery disease.
(16) The case of a 32-year-old man who suffered a blow to his left supraorbital region and eyebrow in an automatic closing door is reported to draw attention to the uncommon but trivial nature of this injury which may result in profound visual loss.
(17) In the paper life-threatening diseases which may be accompanied by profound unconsciousness are explained from the laboratory-chemical point of view.
(18) However pneumonia to PC points to a poor prognosis because they are always associated with a profound deficit or cellular immunity.
(19) Thus, it is possible that the loss of these dendritic cells may contribute to the profound immunological abnormalities seen in AIDS.
(20) They produce a more profound effect on clinical and biochemical aspects of rheumatoid arthritis than do the aspirin-like non steroidals.
(1) Labour’s vertiginous decline in Scotland has shrivelled what used to be the primary unionist party north of the border.
(2) We report on the therapeutic effect of a combination of piracetam and dihydroergocristine in 55 vertiginous patients, of both sexes, between 20 and 67 years of age, from different causes (not scheduled for surgery).
(3) Vestibular nerve section, however, converts this active lesion to a static peripheral lesion, allowing for brainstem compensation and cessation of optokinetic-induced vertiginous symptoms.
(4) Peripheral labyrinthine abnormalities are responsible for the majority of vertiginous symptoms.
(5) Its infamous clubs – The Viper Room, Whisky A Go Go – are the backdrops for a thousand rock memoirs; its vertiginous hills contain more celebrity homes per square mile than anywhere else in the world.
(6) • Rorbu for four from £140 a night, svinoya.no Grande Hytteutleige, Geirangerfjord Facebook Twitter Pinterest Waterfalls, vertiginous green slopes and a meandering, idyllic waterway explain why Unesco-protected Geirangerfjord is one of Norway’s premier tourist spots.
(7) In the acute, vertiginous phase of the disease, the VOR time constant was reduced but was almost normalized 1 year later, both among patients who regained normal caloric side-difference and among those who did not.
(8) There is no question that dizziness and vertiginous-like symptoms occur in children.
(9) In this group, the 1985 guidelines indicate that only 35% of the patients had significant relief of their vertiginous symptoms and 47% had hearing loss greater than 10 dB postoperatively.
(10) The case of a sixty years old man with vague vertiginous feeling, headache and moderate ocular troubles is presented.
(11) The test was performed in Ménière's disease (16 cases), other vertiginous disorders (23 cases) and normal subjects (10 cases).
(12) Since the vestibulospinal level of vestibular function is frequently neglected in the evaluation of vertiginous patients, we developed a new posture equilibrometer for recording body swaying X (left-right) and Y (fore-aft) components of angular displacement, velocity, and acceleration with its transducer on the head of the subject.
(13) The movement of the body's center of gravity was calculated in normal subjects and in vertiginous patients by using a strain gauge platform system and a ditigal computer.
(14) Afterwards he drove us into the mountains, taking us along vertiginous dirt roads in his 4x4, to the places where he kept his hives.
(15) Berlin: The Land of Cockaigne by Heinrich Mann Mann, brother of Thomas, wrote Berlin in the tradition of the bildungsroman , and the introduction to the 1929 English edition offers fair summary: “Andrew Zumsee rises steadily, jesuitically, through the coarse social strata of bourgeois Berlin, behind the skirts of women, via boudoir wire-pulling, to an hour of vertiginous triumph, or at least an illusion thereof.” Life, as in many of these novels, is speculative: “I don’t know what it is that they call transacting business; but it certainly doesn’t take much time … It’s a lazy man’s Heaven, a perfect land of Cockaigne.” 10.
(16) But with land prices rising vertiginously in overcrowded Delhi, officials say foreign investors are lining up to take part.
(17) You’re getting sacked in the morning,” also came down, unsparingly, from the most vertiginous part of the Leazes End.
(18) It is also true that the stakes couldn’t be more vertiginous for David Cameron.
(19) We observed the same results in other vertiginous disorders.
(20) These results corresponded with the clinical findings that the degree of Lpi increases prior to vertiginous episodes in Meniere's patients.