(v. t.) To produce or form cells; especially, to produce cells rapidly.
(v. t.) To produce zooids by budding.
Example Sentences:
(1) The most actively proliferating region of the excurrent duct system is zone 3 of the epididymis, whereas the least active region is the ductuli efferentes.
(2) We also show that proliferation of primary amnion cells is not dependent on a high c-fos expression, suggesting that the function of c-fos is more likely to be associated with other cellular functions in the differentiated amnion cell.
(3) However, when cross-linked to anti-CD4 or anti-CD8 antibodies a markedly enhanced proliferation of the corresponding subpopulation is observed.
(4) Quantitative determinations indicate that the amount of PBG-D mRNA is modulated both by the erythroid nature of the tissue and by cell proliferation, probably at the transcriptional level.
(5) In addition to their involvement in thrombosis, activated platelets release growth factors, most notably a platelet-derived growth factor (PDGF) which may be the principal mediator of smooth muscle cell migration from the media into the intima and of smooth muscle cell proliferation in the intima as well as of vasoconstriction.
(6) 10D1 mAb induced a substantial proliferation of peripheral blood T cells when cross-linked with goat anti-mouse Ig antibody.
(7) Proliferation assays using F3 showed that 15 (14 CD4+ and 1 CD8+) of the 18 isolated clones were specific for T. gondii.
(8) After vascular injury, smooth muscle cells proliferate, reaching a maximum rate at day 2.
(9) Recent studies have shown that an aberration in platelet-derived growth factor gene expression is unlikely to be a factor in proliferation of smooth-muscle cells.
(10) During capillary growth when endothelial cells (EC) undergo extensive proliferation and migration and pericytes are scarce, hyaluronic acid (HA) levels are elevated.
(11) The macrophage-derived product, interleukin 1 (IL 1) is thought to play an important regulatory role in the proliferation of T lymphocytes; however, its mechanism of action is unknown.
(12) T cell costimulation by molecules on the antigen presenting cell (APC) is required for optimal T cell proliferation.
(13) Our prospective study has defined a number of important variables in patients with clinical evidence of mast cell proliferation that can predict both the presence of SMCD and the likelihood of fatal disease.
(14) However, a highly significant upward shift of the proliferating cell compartment was observed in the cancer group, resulting in a specific modification of the [3H]TDR labeling pattern in 6 of 17 specimens.
(15) Anti-5'-NT antibodies had no effect on PHA-induced proliferation.
(16) The mechanism by which gp55 causes increased erythroblastosis and ultimately leukaemia is unknown, but a reasonable suggestion is that gp55 can mimic the action of erythropoietin by binding to its receptor (Epo-R), thereby triggering prolonged proliferation of erythroid cells.
(17) Extensive proliferation has been shown to accompany the de novo generation of LAK cytotoxicity.
(18) Proliferating cells were abundant and scattered throughout the stratified epithelium before the appearance of villi.
(19) Proliferation of quiescent hematopoietic stem cells, purified by cell sorting and evaluated by spleen colony assay (CFU-S), was investigated by measuring the total cell number and CFU-S content and the DNA histogram at 20 and 48 hours of liquid culture.
(20) Whereas the growth and division of normal cells is carefully regulated to meet the needs of the body, tumor cells proliferate autonomously and continually, eventually interfering with and destroying the functions of normal tissue.
Protract
Definition:
(v. t.) To draw out or lengthen in time or (rarely) in space; to continue; to prolong; as, to protract an argument; to protract a war.
(v. t.) To put off to a distant time; to delay; to defer; as, to protract a decision or duty.
(v. t.) To draw to a scale; to lay down the lines and angles of, with scale and protractor; to plot.
(v. t.) To extend; to protrude; as, the cat can protract its claws; -- opposed to retract.
(n.) Tedious continuance or delay.
Example Sentences:
(1) AL-ST works with another dose distribution in time than the conventional brachytherapy, so a higher fractionation of high-dose-rate afterloading is substituted for the classical protraction of low-dose-rate brachytherapy.
(2) Whereas a protracted inhibitory activity is observed in haemophiliacs after replacement therapy (isoantibodies) as well as in acquired haemophilia (autoantibodies), immediate inhibition is characteristic of antibodies directed against phospholipids.
(3) A small number of children with protracted diarrhoea, who have severe mucosal injury may not be able to handle even starch and may require diets based on short chain glucose polymers.
(4) The effects of maxillary protracting bow appliance were the maxillary forward movement associated with counter-clockwise rotation of the nasal floor and the mandibular backward movement associated with clockwise rotation.
(5) A high responsiveness to SCW antigens was seen more frequently in sarcoidosis patients with protracted clinical course.
(6) A downward protraction force produced relatively uniform stress distributions, indicating the importance of the force direction in determining the stress distributions from various orthopedic forces.
(7) Reports in the literature suggest a poor prognosis in the presence of this complication, because of protracted renal damage and chronic renal failure.
(8) However, in the majority (53%) of patients, late recurrence was local and survival subsequent to treatment of these metastases was often protracted, emphasizing the importance of long-term follow-up in all patients with cutaneous melanoma.
(9) According to data in the literature the hormetic effect comprises stimulation of the immune system, a general increase of the resistance of the organism, a reduced risk of cancer and in model organisms a protraction of the median life span was observed.
(10) Human cancers undergo protracted complex development from benign to malignant states, as most thoroughly documented in the mole-to-melanoma sequence.
(11) Pouch young are born prior to retinal innervation of the primary visual centers and spend a protracted period of development in the pouch, making them ideal for visual, developmental studies.
(12) They say an increasing number of “protracted refugees” living in centres in Jordan, Lebanon, Turkey and Iraq will attempt the treacherous journey to Europe because they cannot offer their families a life or a future in the camps.
(13) The duration of the pre-ejection period of the systole, the Q-Kd interval and Achilles tendon reflex was protracted.
(14) Initial clinical trials utilized a daily schedule of administration, which led to severe and protracted myelosuppression and inadequate evaluation of the antitumor spectrum of mitomycin-C.
(15) Immature granulocytes would not exit through a restrictive barrier even after protracted periods and were not responsive to chemoattractants.
(16) The predominant clinical characteristic of this complication was protracted pancytopenia, which required 2 to 5 months recovery time after treatment and did not resolve in one patient.
(17) RBE values increased as dose was protracted, largely due to the reduced effectiveness of protracted gamma irradiation; however, about 28% of the increase can be attributed to the increase in neutron-induced injury caused by dose protraction.
(18) I have not known any time in my half century in this business in which we have had this many simultaneous, complex and protracted crises, of no solution right now.
(19) Within each layer deriving from the cortical plate (layers VIa to II-III), GABA-immunoreactivity showed a protracted maturation in which the first GABA-positive cells were detected a few days after cell birth but substantial numbers of neurons began to express GABA considerably later.
(20) Dose response curves for acute and protracted exposures have been obtained for cells derived from patients with cancer-prone syndromes including ataxia telangiectasia (AT) and Bloom's syndrome.