What's the difference between proliferation and spread?

Proliferation


Definition:

  • (n.) The continuous development of cells in tissue formation; cell formation.
  • (n.) The production of numerous zooids by budding, especially when buds arise from other buds in succession.

Example Sentences:

  • (1) The most actively proliferating region of the excurrent duct system is zone 3 of the epididymis, whereas the least active region is the ductuli efferentes.
  • (2) We also show that proliferation of primary amnion cells is not dependent on a high c-fos expression, suggesting that the function of c-fos is more likely to be associated with other cellular functions in the differentiated amnion cell.
  • (3) However, when cross-linked to anti-CD4 or anti-CD8 antibodies a markedly enhanced proliferation of the corresponding subpopulation is observed.
  • (4) Quantitative determinations indicate that the amount of PBG-D mRNA is modulated both by the erythroid nature of the tissue and by cell proliferation, probably at the transcriptional level.
  • (5) In addition to their involvement in thrombosis, activated platelets release growth factors, most notably a platelet-derived growth factor (PDGF) which may be the principal mediator of smooth muscle cell migration from the media into the intima and of smooth muscle cell proliferation in the intima as well as of vasoconstriction.
  • (6) 10D1 mAb induced a substantial proliferation of peripheral blood T cells when cross-linked with goat anti-mouse Ig antibody.
  • (7) Proliferation assays using F3 showed that 15 (14 CD4+ and 1 CD8+) of the 18 isolated clones were specific for T. gondii.
  • (8) After vascular injury, smooth muscle cells proliferate, reaching a maximum rate at day 2.
  • (9) Recent studies have shown that an aberration in platelet-derived growth factor gene expression is unlikely to be a factor in proliferation of smooth-muscle cells.
  • (10) During capillary growth when endothelial cells (EC) undergo extensive proliferation and migration and pericytes are scarce, hyaluronic acid (HA) levels are elevated.
  • (11) The macrophage-derived product, interleukin 1 (IL 1) is thought to play an important regulatory role in the proliferation of T lymphocytes; however, its mechanism of action is unknown.
  • (12) T cell costimulation by molecules on the antigen presenting cell (APC) is required for optimal T cell proliferation.
  • (13) Our prospective study has defined a number of important variables in patients with clinical evidence of mast cell proliferation that can predict both the presence of SMCD and the likelihood of fatal disease.
  • (14) However, a highly significant upward shift of the proliferating cell compartment was observed in the cancer group, resulting in a specific modification of the [3H]TDR labeling pattern in 6 of 17 specimens.
  • (15) Anti-5'-NT antibodies had no effect on PHA-induced proliferation.
  • (16) The mechanism by which gp55 causes increased erythroblastosis and ultimately leukaemia is unknown, but a reasonable suggestion is that gp55 can mimic the action of erythropoietin by binding to its receptor (Epo-R), thereby triggering prolonged proliferation of erythroid cells.
  • (17) Extensive proliferation has been shown to accompany the de novo generation of LAK cytotoxicity.
  • (18) Proliferating cells were abundant and scattered throughout the stratified epithelium before the appearance of villi.
  • (19) Proliferation of quiescent hematopoietic stem cells, purified by cell sorting and evaluated by spleen colony assay (CFU-S), was investigated by measuring the total cell number and CFU-S content and the DNA histogram at 20 and 48 hours of liquid culture.
  • (20) Whereas the growth and division of normal cells is carefully regulated to meet the needs of the body, tumor cells proliferate autonomously and continually, eventually interfering with and destroying the functions of normal tissue.

Spread


Definition:

  • (imp. & p. p.) of Spread
  • (v. t.) To extend in length and breadth, or in breadth only; to stretch or expand to a broad or broader surface or extent; to open; to unfurl; as, to spread a carpet; to spread a tent or a sail.
  • (v. t.) To extend so as to cover something; to extend to a great or grater extent in every direction; to cause to fill or cover a wide or wider space.
  • (v. t.) To divulge; to publish, as news or fame; to cause to be more extensively known; to disseminate; to make known fully; as, to spread a report; -- often acompanied by abroad.
  • (v. t.) To propagate; to cause to affect great numbers; as, to spread a disease.
  • (v. t.) To diffuse, as emanations or effluvia; to emit; as, odoriferous plants spread their fragrance.
  • (v. t.) To strew; to scatter over a surface; as, to spread manure; to spread lime on the ground.
  • (v. t.) To prepare; to set and furnish with provisions; as, to spread a table.
  • (v. i.) To extend in length and breadth in all directions, or in breadth only; to be extended or stretched; to expand.
  • (v. i.) To be extended by drawing or beating; as, some metals spread with difficulty.
  • (v. i.) To be made known more extensively, as news.
  • (v. i.) To be propagated from one to another; as, the disease spread into all parts of the city.
  • (n.) Extent; compass.
  • (n.) Expansion of parts.
  • (n.) A cloth used as a cover for a table or a bed.
  • (n.) A table, as spread or furnished with a meal; hence, an entertainment of food; a feast.
  • (n.) A privilege which one person buys of another, of demanding certain shares of stock at a certain price, or of delivering the same shares of stock at another price, within a time agreed upon.
  • (n.) An unlimited expanse of discontinuous points.
  • () imp. & p. p. of Spread, v.

Example Sentences:

  • (1) Muscle weakness and atrophy were most marked in the distal parts of the legs, especially in the gastrocnemius and soleus muscles, and then spread to the thighs and gluteal muscles.
  • (2) Before issuing the ruling, the judge Shaban El-Shamy read a lengthy series of remarks detailing what he described as a litany of ills committed by the Muslim Brotherhood, including “spreading chaos and seeking to bring down the Egyptian state”.
  • (3) The tilt was reproduced with a typical spread of about 10 degrees.
  • (4) Human gingival fibroblasts were allowed to attach and spread on bio-glasses for 1-72 h. Unreactive silica glass and cell culture polystyrene served as controls.
  • (5) I hope this movement will continue and spread for it has within itself the power to stand up to fascism, be victorious in the face of extremism and say no to oppressive political powers everywhere.” Appearing via videolink from Tehran, and joined by London mayor Sadiq Khan and Palme d’Or winner Mike Leigh, Farhadi said: “We are all citizens of the world and I will endeavour to protect and spread this unity.” The London screening of The Salesman on Sunday evening wasintended to be a show of unity and strength against Trump’s travel ban, which attempted to block arrivals in the US from seven predominantly Muslim countries: Iran, Iraq, Libya, Sudan, Somalia, Syria and Yemen.
  • (6) The spatial spread or blur parameter of the blobs was adopted as a scale parameter.
  • (7) We present a mathematical model that is suitable to reconcile this apparent contradiction in the interpretation of the epidemiological data: the observed parallel time series for the spread of AIDS in groups with different risk of infection can be realized by computer simulation, if one assumes that the outbreak of full-blown AIDS only occurs if HIV and a certain infectious coagent (cofactor) CO are present.
  • (8) The agriculture ministry raised the risk level of the virus spreading from moderate to high on Tuesday across the country, at a crucial time for the industry.
  • (9) A television camera scans the spread through microscope optics; computer and special purpose electronics process the video signals to generate run length histograms.
  • (10) Prognoses differ according to the histological type of carcinoma, but therapeutic results are also influenced by osseous involvement or by spread to the lymph nodes.
  • (11) This paper describes a teaching process in which two 4th year medical students learn a family approach to problem solving during a short clerkship of twelve hours spread over four weekly sessions.
  • (12) The type I cells are squamous and give off attenuated sheets of cytoplasm which spread widely over the septal surface; these sheets contain few organelles.
  • (13) Histologically, all 17 lesions were squamous cell carcinomas; 10 lesions being mucosal carcinomas, the remaining 7 lesions mucosal carcinomas spreading beyond the epithelial layer.
  • (14) Previous studies have shown that immunosuppressive therapy permits the growth and spread of inadvertently transplanted malignant cells in man, and, in addition, is associated with a 5 to 6% incidence of de novo cancers in organ homograft recipients who were apparently free of cancer before and at the time of transplantation.
  • (15) Field sizes varied from 3 X 4 to 3 X 12 cm depending on lesion spreading.
  • (16) The stage of a given malignancy, representing the degree of spread of the tumor to its local surroundings or distant sites, is the best predictor of long-term survival.
  • (17) The average length of spreading of the whole type was 14.5 mm, and the average length of spreading of the basal type, 19.6 mm.
  • (18) If mammography becomes a wide spread screening method for early detection of breast cancer, the number of non-true interval cancers could be a feed back on the effectiveness of the screening.
  • (19) The present studies examined the effect of cytosolic protons on electrotonic spread and conduction velocity in cardiac Purkinje fibers.
  • (20) The most effective method of combined therapy of locally spread rhinopharyngeal cancer was polychemotherapy (bleomycetin, methotrexate, vinblastine, and cyclophosphamide) before irradiation with subsequent maintenance cyclophosphamide chemotherapy once in 4 weeks for 3-6 months.