(a.) To extend in space or length; as, to prolong a line.
(a.) To lengthen in time; to extend the duration of; to draw out; to continue; as, to prolong one's days.
(a.) To put off to a distant time; to postpone.
Example Sentences:
(1) Without medication atypical ventricular tachycardia develops, in the author's opinion, most probably when bradycardia has persisted for a prolonged period.
(2) Disease stabilisation was associated with prolonged periods of comparatively high plasma levels of drug, which appeared to be determined primarily by reduced drug clearance.
(3) In Patient 2 they were at first paroxysmal and unformed, with more prolonged metamorphopsia; later there appeared to be palinoptic formed images, possibly postictal in nature.
(4) Morphological alterations in the lungs of pheasants after prolonged high-dosage administration of bleomycin sulfate were studied by light and electron microscopy.
(5) Graft life is even more prolonged with patch angioplasty at venous outflow stenoses or by adding a new segment of PTFE to bypass areas of venous stenosis.
(6) We evaluated the circadian pattern of gastric acidity by prolonged intraluminal pHmetry in 15 "responder" and 10 "nonresponder" duodenal ulcer patients after nocturnal administration of placebo, ranitidine, and famotidine.
(7) As prolongation of the action potential by TEA facilitates preferentially the hormone release evoked by low (ineffective) frequencies, it is suggested that a frequency-dependent broadening of action potentials which reportedly occurs on neurosecretory neurones may play an important role in the frequency-dependent facilitation of hormone release from the rat neurohypophysis.
(8) Prolonged immobilization was accompanied by a decrease in Ca-concentration dependence of Ca2+ uptake.
(9) Defibrotide prevents the dramatic fall of creatine phosphokinase activity in the ischemic ventricle: metabolic changes which reflect changes in the cells affected by prolonged ischemia.
(10) With prolonged ischemia, it is only transient and is followed by a gradual loss of the adenylyl cyclase activity.
(11) The authors conclude that H. pylori alone causes little or no effect on an intact gastric mucosa in the rat, that either intact organisms or bacteria-free filtrates cause similar prolongation and delayed healing of pre-existing ulcers with active chronic inflammation, and that the presence of predisposing factors leading to disruption of gastric mucosal integrity may be required for the H. pylori enhancement of inflammation and tissue damage in the stomach.
(12) The mechanism by which gp55 causes increased erythroblastosis and ultimately leukaemia is unknown, but a reasonable suggestion is that gp55 can mimic the action of erythropoietin by binding to its receptor (Epo-R), thereby triggering prolonged proliferation of erythroid cells.
(13) This condition may be caused by the prolonged, repetitive elevations of gonadal steroids and other hormones known to suppress gonadotropin-releasing hormone secretion that are elicited by their daily exercise.
(14) There was no correlation between disturbed gastric clearance, impaired gall bladder contraction, and prolonged colonic transit time in the patients with cardiovascular autonomic neuropathy nor was there a correlation between any disturbed motor function and age or duration of diabetes.
(15) Attempts were made to prolong the survival of the grafts by the use of cytotosine arabinoside, methylprednisolone, heparin and azathioprine.
(16) Because of these different direct and indirect actions, a sudden cessation of sinus node activity or sudden AV block may result in the diseased heart in a prolonged and even fatal cardiac standstill, especially if the tolerance to ischemia of other organs (notably the brain) is decreased.
(17) The 14-fold increase in prolonged apnea frequency immediately following regurgitation supports the hypothesis for a causal relationship between apnea and regurgitation.
(18) Chromatolysis and swelling of the cell bodies of cut axons are more prolonged than after optic nerve section and resolve in more central regions of retina first.
(19) Cryopreserved autologous blood cells may thus restore some patients with CGL in transformation to chronic-phase disease and so may help to prolong life.
(20) Heparin prolonged by 15 s and 45 s the time required to demonstrate Factor V activation in CAP supplemented with Factor Xa and thrombin respectively.
Protract
Definition:
(v. t.) To draw out or lengthen in time or (rarely) in space; to continue; to prolong; as, to protract an argument; to protract a war.
(v. t.) To put off to a distant time; to delay; to defer; as, to protract a decision or duty.
(v. t.) To draw to a scale; to lay down the lines and angles of, with scale and protractor; to plot.
(v. t.) To extend; to protrude; as, the cat can protract its claws; -- opposed to retract.
(n.) Tedious continuance or delay.
Example Sentences:
(1) AL-ST works with another dose distribution in time than the conventional brachytherapy, so a higher fractionation of high-dose-rate afterloading is substituted for the classical protraction of low-dose-rate brachytherapy.
(2) Whereas a protracted inhibitory activity is observed in haemophiliacs after replacement therapy (isoantibodies) as well as in acquired haemophilia (autoantibodies), immediate inhibition is characteristic of antibodies directed against phospholipids.
(3) A small number of children with protracted diarrhoea, who have severe mucosal injury may not be able to handle even starch and may require diets based on short chain glucose polymers.
(4) The effects of maxillary protracting bow appliance were the maxillary forward movement associated with counter-clockwise rotation of the nasal floor and the mandibular backward movement associated with clockwise rotation.
(5) A high responsiveness to SCW antigens was seen more frequently in sarcoidosis patients with protracted clinical course.
(6) A downward protraction force produced relatively uniform stress distributions, indicating the importance of the force direction in determining the stress distributions from various orthopedic forces.
(7) Reports in the literature suggest a poor prognosis in the presence of this complication, because of protracted renal damage and chronic renal failure.
(8) However, in the majority (53%) of patients, late recurrence was local and survival subsequent to treatment of these metastases was often protracted, emphasizing the importance of long-term follow-up in all patients with cutaneous melanoma.
(9) According to data in the literature the hormetic effect comprises stimulation of the immune system, a general increase of the resistance of the organism, a reduced risk of cancer and in model organisms a protraction of the median life span was observed.
(10) Human cancers undergo protracted complex development from benign to malignant states, as most thoroughly documented in the mole-to-melanoma sequence.
(11) Pouch young are born prior to retinal innervation of the primary visual centers and spend a protracted period of development in the pouch, making them ideal for visual, developmental studies.
(12) They say an increasing number of “protracted refugees” living in centres in Jordan, Lebanon, Turkey and Iraq will attempt the treacherous journey to Europe because they cannot offer their families a life or a future in the camps.
(13) The duration of the pre-ejection period of the systole, the Q-Kd interval and Achilles tendon reflex was protracted.
(14) Initial clinical trials utilized a daily schedule of administration, which led to severe and protracted myelosuppression and inadequate evaluation of the antitumor spectrum of mitomycin-C.
(15) Immature granulocytes would not exit through a restrictive barrier even after protracted periods and were not responsive to chemoattractants.
(16) The predominant clinical characteristic of this complication was protracted pancytopenia, which required 2 to 5 months recovery time after treatment and did not resolve in one patient.
(17) RBE values increased as dose was protracted, largely due to the reduced effectiveness of protracted gamma irradiation; however, about 28% of the increase can be attributed to the increase in neutron-induced injury caused by dose protraction.
(18) I have not known any time in my half century in this business in which we have had this many simultaneous, complex and protracted crises, of no solution right now.
(19) Within each layer deriving from the cortical plate (layers VIa to II-III), GABA-immunoreactivity showed a protracted maturation in which the first GABA-positive cells were detected a few days after cell birth but substantial numbers of neurons began to express GABA considerably later.
(20) Dose response curves for acute and protracted exposures have been obtained for cells derived from patients with cancer-prone syndromes including ataxia telangiectasia (AT) and Bloom's syndrome.