(1) At ambient temperature the benzylidene hydrazide of 3-(3,4-dimethoxyphenyl)propenic acid (VII) and a small amount of compound VIII were isolated.
(2) The mutagenic activities of mixtures of nitrogen dioxide and 1,3-butadiene or propene were investigated after uv-irradiation in a small, laboratory-bench scale flow-through gas exposure system.
(3) Feeding 1-amino-3-imino N,N' propene diacetate (AIPD) produced 2 metabolic by products with active aldehyde groups 1-amino propenal acetic acid (APA) and malonyldialdehyde (MDA) that transiently block the lysine epsilon-amino groups of all proteins and lipoproteins in vivo.
(4) Acute toxicity is believed to involve metabolism of allylamine to highly reactive acrolein (2-propenal).
(5) Vinylogous hydroxamic acids (3-(N-hydroxy-N-alkylamino)-2-propen-1-ones, VHA) were prepared as antiinflammatory agents.
(6) (E)- and (Z)-1,2,3-triphenyl-2-propen-1-ones and some of their phenolic and alkoxy analogues, substituted at the para position in one or more of the aromatic rings, were synthesized and assigned geometry on the basis of their spectroscopic data.
(7) All the data taken together suggested that the RPS's were the stereoisomer of 3-(2-ethyl-5-hydroxy-3-oxo) cyclopentanyl-2-propenal.
(8) 1-(2,6-Dihydroxy-4-methoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-o ne, C17H16O5, Mr = 300.31, orthorhombic, Pbca, a = 27.903 (3), b = 13.958 (2), c = 7.662 (1) A, V = 2984 (1) A3, Z = 8, D chi = 1.337 Mg m-3, lambda(Cu K alpha) = 1.5418 A, mu = 0.729 mm-1, F(000) = 1264, T = 295 K, R = 0.040 for 1702 observed reflections.
(9) The 5'-monophosphate oligonucleotide ends produced from thymine propenal formation have been converted to inorganic phosphate by the action of alkaline phosphatase, and the phosphate has been analyzed for 18O content by 31P NMR spectroscopy.
(10) 1-(Fluoren-2-yl)-2-propen-1-one (vinyl fluorenyl ketone, VFK) was shown to be a potent and irreversible inactivator of NAT II activities.
(11) These data suggest a mechanism of inactivation which involves the transamination of the nascent product to the pyruvoyl group, followed by the elimination of methylthioadenosine and the generation of a 2-propenal equivalent which could undergo a Michael addition to the enzyme.
(12) In the reaction of 3-(3,4-dimethoxyphenyl)propenic acid chloride with benzylidene hydrazide (VII) at 70-80 degrees C, compound VIII was obtained (Scheme 1).
(13) Treatment of calf thymus deoxyribonucleic acid (DNA) with bleomycin-Fe(II) at 0 degree C for 5 min resulted in the formation of 8-hydroxyguanine (8-OH-Gua) residues in DNA in a dose dependent manner, in addition to the formation of base propenal, a DNA-degradation product.
(14) It is a useful intermediate in the preparation of a new class of chromophoric spin label substrates for enzyme studies, as shown by the synthesis of O-3-(2,2,5,5-tetramethylpyrroline-1-oxyl)-propen-2-oyl-L-beta-phenyllactic acid, a specific ester substrate of bovine pancreatic carboxypeptidase A (peptidyl-L-amino acid hydrolase; EC 3.4.12.2).
(15) We have identified a new radiation product (thymin-1'-yl)-propenal as the TBA-reactive product of gamma-irradiation of thymidine.
(16) These phosphate-containing compounds increase both the release of free nucleic base and that of base propenals which are DNA cleavage products, probably by enhancing the efficiency with which Fe(II) is recruited into the drug.
(17) From 3-(3,4-dimethoxyphenyl)propenic acid chloride and substituted amines and hydrazides, the appropriate amides and hydrazides (Table 1) were synthesized at 60-80 degrees C in the medium of benzene or toluene.
(18) Approximately 0.25 ppm butadiene, compared to 100 ppm propene, was needed to give a significant mutagenic effect with 0.25 ppm NO2 after 6 hr exposure.
(19) Male CBA mice were exposed to propene, unlabelled or 14C-labelled, by inhalation, or to 14C-labelled propylene oxide by intraperitoneal injection.
(20) An approximate 1:4 ratio was observed between butadiene and propene which both originate predominantly from vehicle exhaust.
Propone
Definition:
(v. t.) To propose; to bring forward.
Example Sentences:
(1) Although it appears to come within the confines of privacy, assisted suicide constitutes a more radical change in the law than its proponents suggest.
(2) Both sides agree that antigenic diversity is advantageous although selectionists see benefits in individual mutations whereas the proponents of random genetic drift see the advantage in the parasite's capacity to tolerate diversity per se.
(3) It is said that the science around climate change is not as certain as its proponents allege.
(4) He is also a vocal proponent of the benefit cap , finding it disgusting that some families can claim more in benefits than the average person earns, even while he finds it intolerable that he can only claim in accommodation expenses £2,000 more than the cap .
(5) He is a “caricature machine politician” , Goldsmith has claimed, but also the proponent of “divisive and radical politics” .
(6) Hungary, now one of Europe’s keenest proponents of border protection, was less than a century ago part of a polyglot, multinational commonwealth, the Austro-Hungarian empire.
(7) George Osborne, the chancellor, whose Tatton constituency lies on the expected route, is a crucial proponent in unlocking the £33bn spend.
(8) Queen Victoria’s physician was a great proponent of the value of tincture of cannabis and the monarch is reputed to have used it to counteract the pain of menstrual periods and childbirth.
(9) Soviet leader Mikhail Gorbachev was the major proponent of Greater Europe, a concept that also had European roots in Gaullism and other initiatives.
(10) Debate among proponents of these various proposals might be advanced if a common language were adopted with regard to certain key terms instead of the various meanings currently assigned to these terms.
(11) Psychologist Susan Blackmore is best known as the proponent of memes, but early in her career she was a parapsychologist.
(12) Proponents argue that freestanding emergency centers reduce costs by providing care in a more efficient manner and cause other health care providers such as hospital emergency rooms to reduce costs and improve service.
(13) Strong proponents exist for the combination chemoradiation, whereas others favor radical radiation therapy.
(14) Proponents of these schemes argue that it helps to rescue people from fuel poverty.
(15) But proponents argue a nuclear weapons ban will create a moral case – in the vein of the cluster and land mine conventions – for nuclear weapons states to disarm, and establish a new international norm prohibiting nuclear weapons’ development, possession, and use.
(16) The basic income has its proponents on the right as well as the left, with the former seeing it as a cut-price form of welfare.
(17) It was, I recall, an anarchic traffic jam of ex-squatters, ravers, and proponents of free love that chuntered slowly and messily through the byways and sometimes the highways of Thatcher’s Britain.
(18) According to some proponents and critics of research using animals, the greatest hope for improved conditions for laboratory animals is to be found in the system of self-regulation called for by recent legislation and the NIH's revised policy.
(19) Lord Mandelson, a former Labour minister and a keen proponent of electoral reform, said AV supporters had paid a "big price" for staging the national poll on the same day as the first elections since the general election.
(20) He said the shift to the neutral stance would allow nurses to talk to patients about it if they were questioned, but added: "That must not be confused with us being proponents of assisted suicide."