What's the difference between propine and tropine?

Propine


Definition:

  • (v. t.) To pledge; to offer as a toast or a health in the manner of drinking, that is, by drinking first and passing the cup.
  • (v. t.) Hence, to give in token of friendship.
  • (v. t.) To give, or deliver; to subject.
  • (n.) A pledge.
  • (n.) A gift; esp., drink money.
  • (n.) Same as Allylene.

Example Sentences:

  • (1) This alcohol oxidase oxidizes not only methanol but also lower primary alcohols (C2-C4), 2-propin-1-ol and formaldehyde.
  • (2) Propine contains the following: dipivefrin, 0.1%; mannitol, 1.89%; sodium metabisulfite, 0.075%; disodium edetate, 0.0127%; and benzalkonium chloride, 0.004%.
  • (3) There was no significant difference between the intraocular lowering effect of the two preparations, and 60% of patients receiving Propine and 66% of those receiving adrenaline noted side effects.
  • (4) Iontophoresis was performed once at 0.5 mAmp for five minutes and 0.1% Propine drops were instilled four times a day beginning three days after iontophoresis and continuing for five consecutive days.
  • (5) Dipivefrin alone reproduced each patient's initial Propine-induced conjunctivitis; symptoms occurred unilaterally in one patient and bilaterally in the other four patients.
  • (6) In 12 ulcer patients in attack and in 6 healthy subjects the secretory test to insulin (Hollender test) was used and repeated after 48 hrs in association with propranolol (Propins test).
  • (7) Herpes simplex virus type 1 (HSV-1) ocular shedding and recurrent HSV-1 corneal epithelial lesions were assessed after ocular iontophoresis of 0.1% 6-hydroxydopamine followed by topical ocular instillation of 0.1% Propine in ten rabbits latently infected with HSV-1 strain McKrae.
  • (8) Derivatives of propionic and acetic acids (propinate, dalapon, MCAA, DCAA, and TCAA) did not exhibit any appreciable inhibiting effect under the experimental conditions.
  • (9) Fumarate, 3-phenyl-2-propinate, 2-enoyl-methyl and CoA esters proved not to be substrates for the purified reductase.
  • (10) Dipivefrin (Propine) is an effective ocular hypotensive agent.
  • (11) It therefore results that by using our "Propins" test it is possible to estimate the prevalence of the vagal-cholinergic or the beta-adrenergic (gastrinic) mechanism in the pathogenesis of duodenal ulcer.
  • (12) The facial nerve from the point of view of its arterial supply must be considered as a nerve of the middle fossa and represent the major risk of embolization in the propinal middle meningeal artery.
  • (13) Statistically, both dipivefrin (Propine) and levobunolol (Betagan) were found to be more expensive.
  • (14) We studied five patients with adverse local reactions to dipivefrin (Propine) eye drops.
  • (15) The results of this single-blind randomised trial comparing adrenaline 1% with dipivalyl epinephrine (Propine) 0.1% confirm that both have a significant effect in lowering the intraocular pressure in patients with open-angle glaucoma and ocular hypertension, but it is generally insufficient to warrant their use as the first line medical treatment of these two conditions.

Tropine


Definition:

  • (n.) A white crystalline alkaloid, C8H15NO, produced by decomposing atropine.

Example Sentences:

  • (1) Our findings indicate that endothelial receptors are characterised by a high affinity for scopolamine, which possesses a scopine base, and that muscle binding sites have a high affinity for antagonists possessing a tropine base (atropine, homatropine).
  • (2) Simple benzoyl derivatives of tropine and 3 alpha-aminotropane possessed weak 5HT3 receptor antagonist activity, as judged by blockade of bradycardia produced by iv injection of serotonin (5HT) to anesthetized rats.
  • (3) Noratropine (24%), atropine-N-oxide (equatorial isomer) (15%), tropine (2%) and tropic acid (3%) appear to be the major metabolites, while 50% of the administered dose is excreted as apparently unchanged atropine.
  • (4) Endocrine active substances of interest to the gynecologist produced under these circumstances include gonadotropin, lactogens, thyrotropins, and adrenocortico-tropin, as well as calcium-mobilizing and erythropoietic substances.
  • (5) Localization studies of the hypothalamohypophysial and tuberoinfundibular neurosecretory systems were performed in the adult male mallard duck with an immunoperoxidase techinque for the demonstration of neurophysin (NP) and gonado-tropin-releasing hormone (Gn-RH) and with aldehyde fuchsin for the staining of neuosecretory material (NSM).
  • (6) A 2.0-mL blood specimen containing deuterated N-methyl-atropine as the internal standard was alkaline-hydrolyzed to convert atropine to tropine.
  • (7) The influence of ecgonine, tropine, tropinon, and some of their derivatives, propan, N-methylpyrrholidine, N-methylpiperidine on impulse summation in the central nervous system, conditioned reflex of avoidance, antagonism to hexenal, synergisim to cocaine and also their toxicity (LD50) have been studied under experimental conditions.
  • (8) The fasting plasma concentration of the pituitary peptide beta-cell tropin [beta-CT, adrenocorticotropic hormone-(22-39)] was measured in 17 rhesus monkeys from a colony known to develop spontaneous obesity.
  • (9) beta-Cell tropin, the pituitary peptide ACTH22-39, is a potent insulin secretagogue and stimulates lipogenesis in adipose tissue in rodents.
  • (10) The tropine was extracted by organic solvent which was evaporated to dryness.
  • (11) Tropine p-chlorophenyl acetate (TPClphiA), which differs from TPTA only by the substitution of a p-Cl for a p-CH(3) group on the benzene ring, had a negligible effect on axonal excitability.
  • (12) Structural factors which interfere with the conformational changes occurring in the receptor protein induced by an activator are characterized through differences obtained by the comparative investigation of the activities of the agonist acetate and the antagonist benzilate amino esters of quinuclidine, tropine, and pseudotropine.
  • (13) It was shown that the hypotensive and bradycardiac properties of Gardenia extract were entirely abolished in a tropinized and vagotomized rats, but only partially attenuated in carotid sinus denervated rats, and that low cervical spinal transection in rats did not inhibit the hypotensive responses.
  • (14) Tropine (tropan-3 alpha-ol) is an intermediate in the formation of hyoscyamine.
  • (15) The diabetic subjects had raised fasting plasma beta-cell tropin compared with the normal subjects (geometric mean (1 SD range): 0.49 (0.25-0.96) nM and 0.17 (0.10-0.28) nM, respectively, P = 0.007).
  • (16) Lactating and non-lactating rat brown adipocytes were used to study the dose-dependent stimulation of lipogenesis by Beta-cell tropin (BCT) and insulin.
  • (17) beta-Cell tropin concentrations in the diabetic subjects rose to 1.31 (0.74-2.30) nM (P = 0.007), whereas beta-cell tropin did not change in the normal subjects at 0.19 (0.11-0.91) nM.
  • (18) In two subjects, a biphasic response of both tropins was present.
  • (19) The pharmacokinetics of atropine and its primary metabolite, tropine, were determined simultaneously.
  • (20) A specific tropine alkaloid assay may provide supporting evidence.

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