(1) The findings suggest that mast cell prostaglandins are an important factor in the pathogenesis of pruritus and that local vascular responses may trigger mast cell degranulation.
(2) The most frequent symptom was pruritus associated with burning.
(3) Hypersensitivity reactions, most commonly skin rashes or pruritus, affect about 1% of patients.
(4) The adverse effects were negligible--one patient had light urticarial rash and pruritus.
(5) Intradermal histamine dose-response thresholds of pruritus were obtained before and after pretreatment with the three antihistamines and placebo in each subject.
(6) Side-effects (pruritus, nausea, vomiting, drowsiness) were also noted.
(7) No statistically significant difference for the pruritus score was found.
(8) To this end, Table 1 lists those differential diagnoses that would be considered in human beings who have generalized pruritus unassociated with significant cutaneous pathology.
(9) The illness was associated with eosinophilia, pruritus, and an elevated IgE level, indicating an immunologic pathogenetic mechanism.
(10) Jaundice and pruritus lasted 19 and 20 mo, respectively.
(11) Presenting symptoms included: crampy right upper quadrant pain, jaundice, pruritus, cholangitis, pancreatitis, hepatomegaly, and elevated liver function tests.
(12) The second-generation H1-receptor antagonists are replacing the first generation H1-receptor antagonists in the symptomatic treatment of allergic rhinoconjunctivitis, and in relieving pruritus in patients with urticaria.
(13) All patients were symptomatic with pruritus and were expected to survive three months or more.
(14) Relief of jaundice or pruritus was obtained in 68%, and this figure included a number of patients who died in the first 30 days.
(15) An outbreak of the pruritus, pyrexia, haemorrhagic syndrome affected eight of a herd of 175 cows which was divided into two groups of 115 and 60 according to yield.
(16) Survivors at ages of 19 months to 16.5 years had considerable morbidity with pruritus occurring in 70%, jaundice in 48%, xanthomas in 30%, 74% having hepatomegaly and 63% splenomegaly.
(17) Treatment with astemizole, as measured at the end point of each patient's treatment and compared to placebo, resulted in significant improvement of pruritus, erythema, number of wheals, frequency of urticarial attacks, and control of urticaria (p less than or equal to 0.03).
(18) The only remarkable adverse reaction in the chloroquine group was pruritus which occurred in 7 subjects.
(19) Nevertheless, pruritus, urinary retention, hypotension and severe respiratory depression have been reported with both methods.
(20) Pruritus and hepatomegaly were present in half of the patients.
Skin
Definition:
(n.) The external membranous integument of an animal.
(n.) The hide of an animal, separated from the body, whether green, dry, or tanned; especially, that of a small animal, as a calf, sheep, or goat.
(n.) A vessel made of skin, used for holding liquids. See Bottle, 1.
(n.) The bark or husk of a plant or fruit; the exterior coat of fruits and plants.
(n.) That part of a sail, when furled, which remains on the outside and covers the whole.
(n.) The covering, as of planking or iron plates, outside the framing, forming the sides and bottom of a vessel; the shell; also, a lining inside the framing.
(v. t.) To strip off the skin or hide of; to flay; to peel; as, to skin an animal.
(v. t.) To cover with skin, or as with skin; hence, to cover superficially.
(v. t.) To strip of money or property; to cheat.
(v. i.) To become covered with skin; as, a wound skins over.
(v. i.) To produce, in recitation, examination, etc., the work of another for one's own, or to use in such exercise cribs, memeoranda, etc., which are prohibited.
Example Sentences:
(1) The catheter must be meticulously fixed to the skin to avoid its movement.
(2) Elements in the skin therefore seemed to enhance nerve regeneration and function.
(3) This is a fascinating possibility for solving the skin shortage problem especially in burn cases.
(4) Blood flow decreased immediately after skin expansion in areas over the tissue expander on days 0 and 1 and returned to baseline levels within 24 hours.
(5) These findings suggest that clonidine transdermal disks lower blood pressure in hypertensive patients, but produce local skin lesions and general side effects.
(6) Currently, photodynamic therapy is under FDA-approved clinical investigational trials in the treatment of tumors of the skin, bronchus, esophagus, bladder, head and neck, and of gynecologic and ocular tumors.
(7) Immunofluorescent staining for HLA-DR showed dermal positivity in 12 of 13 involved- and 9 of 13 uninvolved-skin biopsy specimens from scleroderma patients, compared with only 1 of 10 controls.
(8) Blood flow was measured in leg and torso skin of conscious or anesthetized sheep by using 15-micron radioactive microspheres (Qm) and the 133Xe washout method (QXe).
(9) A similar interference colour appeared after incubating sections of rat skin with chymase.
(10) Peptides from this region bind to actin, act as mixed inhibitors of the actin-stimulated S1 Mg2(+)-ATPase, and influence the contractile force developed in skinned fibres, whereas peptides flanking this sequence are without effect in our test systems.
(11) This study was designed to examine the effect of the storage configuration of skin and the ratio of tissue-to-storage medium on the viability of skin stored under refrigeration.
(12) Somatostatin-like immunoreactivity has been found to occur in nerve terminals and fibres of the normal human skin using immunohistochemistry.
(13) We recommend analysing the urine for porphyrins in HIV-positive patients who have chronic photosensitivity of the skin.
(14) We investigated the incidence of skin cancer among patients who received high doses of PUVA to see whether such incidence increased.
(15) Attachment of the graft to the wound is similar with and without the addition of human basic fibroblast growth factor, a potent angiogenic agent, to the skin replacement before graft placement on wounds.
(16) In order to develop a sampling strategy and a method for analyzing the circadian body temperature pattern, we monitored estimates of the temperature in four ways using rectal, oral, axillary and deep body temperature from the skin surface every hour for 72 consecutive hours in 10 normal control subjects.
(17) It was shown that the antibiotic had low acute toxicity, did not cumulate and had no skin-irritating effect.
(18) Compliance during dehydration was 7.6 and 12.5% change in IFV per millimeter Hg fall in IFP (micropipettes) in skin and muscle, respectively, whereas compliance in subcutis based on perforated capsule pressure was 2.0% change in IFV per millimeter Hg.
(19) For the second propositus, a woman presenting with abdominal and psychiatric manifestations, the age of onset was 38 years; the acute attack had no recognizable cause; she had mild skin lesions and initially was incorrectly diagnosed as intermittent acute porphyria; the diagnosis of variegate porphyria was only established at the age of 50 years.
(20) 14 patients with painful neuroma, skin hyperesthesia or neuralgic rest pain were followed up (mean 20 months) after excision of skin and scar, neurolysis and coverage with pedicled or free flaps.