(1) The findings suggest that mast cell prostaglandins are an important factor in the pathogenesis of pruritus and that local vascular responses may trigger mast cell degranulation.
(2) The most frequent symptom was pruritus associated with burning.
(3) Hypersensitivity reactions, most commonly skin rashes or pruritus, affect about 1% of patients.
(4) The adverse effects were negligible--one patient had light urticarial rash and pruritus.
(5) Intradermal histamine dose-response thresholds of pruritus were obtained before and after pretreatment with the three antihistamines and placebo in each subject.
(6) Side-effects (pruritus, nausea, vomiting, drowsiness) were also noted.
(7) No statistically significant difference for the pruritus score was found.
(8) To this end, Table 1 lists those differential diagnoses that would be considered in human beings who have generalized pruritus unassociated with significant cutaneous pathology.
(9) The illness was associated with eosinophilia, pruritus, and an elevated IgE level, indicating an immunologic pathogenetic mechanism.
(10) Jaundice and pruritus lasted 19 and 20 mo, respectively.
(11) Presenting symptoms included: crampy right upper quadrant pain, jaundice, pruritus, cholangitis, pancreatitis, hepatomegaly, and elevated liver function tests.
(12) The second-generation H1-receptor antagonists are replacing the first generation H1-receptor antagonists in the symptomatic treatment of allergic rhinoconjunctivitis, and in relieving pruritus in patients with urticaria.
(13) All patients were symptomatic with pruritus and were expected to survive three months or more.
(14) Relief of jaundice or pruritus was obtained in 68%, and this figure included a number of patients who died in the first 30 days.
(15) An outbreak of the pruritus, pyrexia, haemorrhagic syndrome affected eight of a herd of 175 cows which was divided into two groups of 115 and 60 according to yield.
(16) Survivors at ages of 19 months to 16.5 years had considerable morbidity with pruritus occurring in 70%, jaundice in 48%, xanthomas in 30%, 74% having hepatomegaly and 63% splenomegaly.
(17) Treatment with astemizole, as measured at the end point of each patient's treatment and compared to placebo, resulted in significant improvement of pruritus, erythema, number of wheals, frequency of urticarial attacks, and control of urticaria (p less than or equal to 0.03).
(18) The only remarkable adverse reaction in the chloroquine group was pruritus which occurred in 7 subjects.
(19) Nevertheless, pruritus, urinary retention, hypotension and severe respiratory depression have been reported with both methods.
(20) Pruritus and hepatomegaly were present in half of the patients.
Urticaria
Definition:
(n.) The nettle rash, a disease characterized by a transient eruption of red pimples and of wheals, accompanied with a burning or stinging sensation and with itching; uredo.
Example Sentences:
(1) This initial observation of release of eosinophil chemotactic factor of anaphylaxis in vivo along with histamine assigns the mast cell a central role in cold urticaria.
(2) We report an episode of hypotension, tachycardia, bronchospasm and urticaria following application of a non-ionic contrast medium (Iopamidol) during isoflurane anaesthesia.
(3) This suggests that common food additives are seldom if ever of significance as precipitating factors in chronic urticaria or atopic dermatitis.
(4) An almost equal sex distribution was found in chronic urticaria (51.9% female).
(5) The antimalarial drugs can clear up skin lesions in patients with polymorphous light eruption and solar urticaria who cannot obtain relief with topical sunscreens and in some patients with porphyria cutanea tarda.
(6) Both before and after application of the stimulus, the walls of the superficial dermal vessels of the patients with dermographism were thinner and contained less extracellular matrix material than vessel walls of the patients with cold-induced urticaria.
(7) Localized heat urticaria is a rare disorder, in which the nature of the mediator is not fully established.
(8) (2) One case (1.3%) of minor degree of urticaria was found as a side effect, and one case each of eosinophilia and elevation of GOT, GPT and Al-P was observed as abnormal laboratory value.
(9) The drug was withdrawn in 6 patients--lack of response in one, thrombocytopenia in one, urticaria in one, rash in one, and granulocytopenia in 2.
(10) A young woman with diabetes mellitus developed chronic urticaria after changing from isophane been insulin suspension to isophane beef-pork insulin suspension.
(11) A frequent cause of contact urticaria is skin exposure to the common stinging nettle (Urtica dioica).
(12) Different reaction types seem to have been responsible for the occurrence of the urticaria.
(13) The second-generation H1-receptor antagonists are replacing the first generation H1-receptor antagonists in the symptomatic treatment of allergic rhinoconjunctivitis, and in relieving pruritus in patients with urticaria.
(14) These results indicate that a 10 day trial of both H1 and H2 antihistamines may be useful in patients with chronic urticaria resistant to all other standard treatment modalities.
(15) A case is here reported of a 35 year old woman with a history of urticaria following anti-tetanus serum and penicillin injections, who frequently ate exotic fruit, and who was intolerant to alcohol.
(16) In children, manifestations of IgE-mediated food allergy (often in association with other immune mechanisms) include self-limiting and immediate reactions (e.g., urticaria, wheeze) and chronic diseases (food-sensitive enteropathies, eczema).
(17) Histamine release from peripheral blood basophils challenged with C5a, f-met-peptides and calcium ionophore was studied in patients with cold urticaria before and after exposure to low environmental temperatures.
(18) Many solar urticaria patients may benefit from the use of antihistamines.
(19) The predominant signs were facial edema, flushing, urticaria, bronchospasm, tachycardia, and hypotension.
(20) The association of chronic urticaria with C3NeF without clinical and biological signs of membranoproliferative glomerulonephritis and partial lipodystrophy has not to our knowledge been reported before.