(1) Tricyclic antidepressants are often associated with adverse drug reactions in the elderly, so alternatives such as MAO inhibitors, alprazolam, bupropion and psychostimulants are currently being explored in this patient population.
(2) CEEG profiles of LHM in low dosages (less than or equal to 10 mcg) are similar to CNS "inhibitory" compounds, while in higher dosages (25 mcg to 100 mcg) they resemble "psychostimulant" compounds.
(3) Its application was characterized by a faster onset of the therapeutic effect and a peculiar mild psychostimulating action, primarily manifested in the impact on obligate manifestations of the asthenic disorders.
(4) This effect appeared unrelated to their effect on depression although a differential effect of the two psychostimulants on anxiety was observed.
(5) Considerations pertaining to treatment with heterocyclic drugs, MAOIs, lithium, psychostimulants and thyroid hormone, as well as ECT, have been reviewed.
(6) A quantitative pharmaco-EEG analysis of the action of psychostimulant drug sydnocarb and its solvent polyethylenglycol-400 on bioelectrical activity of sensomotor cortex, dorsal hippocamp and lateral hypothalamus of wakeful rats in free behavior was carried out.
(7) The reinforcing properties of amfonelic acid, a nonamphetamine psychostimulant, were evaluated in an intravenous self-administration paradigm.
(8) The computer EEG (CEEG) profiles of both formulations are not only very similar to each other, but also resemble the CEEG profiles of psychostimulant compounds (Bio-availability).
(9) It has been shown that oral administration in therapeutic doses of the psychostimulant sydnocarb optimizes the mnemonic processes.
(10) The ventral tegmental area is a site of action by psychostimulants in the production of behavioral sensitization.
(11) A distinction between the effects of opiates and psychostimulants on reinforced responding is hypothesized based on differential modulation of dopamine release.
(12) as well as by a psychostimulant effect similar to that of amphetamine which occurs through the release of dopamine.
(13) The authors assessed the influence of psychostimulants on relearning of rats of the avoidance direction in a Y-maze.
(14) An augmentation of psychostimulant-induced motor activity, termed sensitization, occurs with daily treatment and can last for months or years.
(15) Antidepressants could thus be distinguished from psychostimulants which decreased immobility at doses which increased general activity.
(16) They also found that a substantial number of psychiatrists who regularly prescribe MAOIs also report prescribing high doses and combining therapy with tricyclics, lithium, neuroleptics, and psychostimulants.
(17) The xanthine adenosine antagonists have mild psychostimulant, analgesic adjuvant, diuretic, cardiotonic and antiasthmatic activity.
(18) The most commonly used classes of psychiatric medicines, including antidepressants, CNS depressants, benzodiazepines, antipsychotics, psychostimulants, and lithium carbonate, are reviewed as to their potential interactions with alcohol.
(19) In addition, they provide a specific basis for ameliorative treatment with psychostimulant medication.
(20) Three adults with DSM-III-R diagnoses of attention deficit hyperactivity disorder were treated with a combination of a psychostimulant and nadolol.
Stimulant
Definition:
(a.) Serving to stimulate.
(a.) Produced increased vital action in the organism, or in any of its parts.
(n.) That which stimulates, provokes, or excites.
(n.) An agent which produces a temporary increase of vital activity in the organism, or in any of its parts; -- sometimes used without qualification to signify an alcoholic beverage used as a stimulant.
Example Sentences:
(1) Stimulation of human leukocytes with various chemical mediators such as TPA, f-Met-Leu-Phe, LTB4, etc.
(2) The optimal size for stimulation was between 5 degrees and 12 degrees (visual angle).
(3) After stimulation with lipopolysaccharide and calcium ionophore A23187, culture supernatants of clones c18A and c29A showed cytotoxic activity against human melanoma A375 Met-Mix and other cell lines which were resistant to the tumor necrosis factor, lymphotoxin and interleukin 1.
(4) Apparently, the irradiation with visible light of a low intensity creates an additional proton gradient and thus stimulates a new replication and division cycle in the population of cells whose membranes do not have delta pH necessary for the initiation of these processes.
(5) In conclusion, in S-rats a glucose-stimulated insulin release is accompanied by an increase in IBF, but this is not observed in P-rats.
(6) Stimulation is also observed with mixtures of APC expressing DPw3 and APC expressing A1, and likewise, DPw3+ APC become stimulatory when preincubated with supernatants from A1-positive cells.
(7) We have previously shown that serotonin is present in secretory granules of frog adrenochromaffin cells; concurrently, we have demonstrated that serotonin is a potent stimulator of corticosterone and aldosterone secretion by adrenocortical cells.
(8) Cyclic AMP stimulated phosphorylation by [gamma-32P]ATP of two proteins of apparent Mr = 20,000 and 7,000 that were concentrated in sarcoplasmic reticulum, but the stimulation was markedly dependent on the presence of added soluble cyclic AMP-dependent protein kinase.
(9) We have investigated a physiological role of endogenous insulin on exocrine pancreatic secretion stimulated by a liquid meal as well as exogenous secretin and cholecystokinin octapeptide (CCK-8) in conscious rats.
(10) Whether hen's egg yolk can be used as a sperm motility stimulant in the treatment of such conditions as asthenospermia and oligospermia is subjected for further study.
(11) Some of those drugs are able to stimulate the macrophages, even in an aspecific way, via the gut associated lymphatic tissue (GALT), that is in connection with the bronchial associated lymphatic tissue (BALT).
(12) The results also suggest that the dispersed condition of pigment in the melanophores represents the "resting state" of the melanophores when they are under no stimulation.
(13) dl-Methionine stimulated the synthesis of cephalosporins when added after the growth phase.
(14) Bradykinin also stimulated arachidonic acid release in decidual fibroblasts, an effect which was potentiated in the presence of epidermal growth factor (EGF), but which was not accompanied by an increase in PGF2 alpha production.
(15) Pokeweed mitogen-stimulated rat spleen cells were identified as a reliable source of rat burst-promoting activity (PBA), which permitted development of a reproducible assay for rat bone marrow erythroid burst-forming units (BFU-E).
(16) To investigate the mechanism of enhanced responsiveness of cholesterol-enriched human platelets, we compared stimulation by surface-membrane-receptor (thrombin) and post-receptor (AlF4-) G-protein-directed pathways.
(17) Estimates of potential for gastrointestinal side effects using the rat enteropooling assay and in vivo monkey effects indicate that diarrhea will be substantially reduced with retention of uterine stimulating potency.
(18) Because it has been suggested that the lathyrogen, BAPN, may stimulate the release of proteases, the protease inhibitors Trasylol and epsilon-aminocaproic acid (EACA) were given alone or in combination to BAPN-treated rats.
(19) The present study was designed to test the hypothesis that the decreased Epi response following ET was due to 1) depletion of adrenal Epi content such that adrenomedullary stimulation would not release Epi, 2) decreased Epi release with direct stimulation, i.e., desensitization of release, or 3) decreased afferent signals generated by ET itself.
(20) Stimulation of atrial H1-receptors is suggested to directly cause an increase in Ca-channel conductance independent of intracellular cAMP content.