(n.) The earliest age at which persons are capable of begetting or bearing children, usually considered, in temperate climates, to be about fourteen years in males and twelve in females.
(n.) The period when a plant first bears flowers.
Example Sentences:
(1) These results do not support the view that in the rat pheromones from adult males enhance puberty in females, contrary to what is known to happen in the mouse.
(2) In contrast, idiopathic GH deficient girls have an onset of puberty and PHV nearer to a normal chronological age and at an early bone age.
(3) We report the treatment of 44 boys with constitutional delay of growth and puberty (CDGP) at a mean chronological age of 14.3 years (range, 12.4-17.1) and bone age of 12.1 years (range, 9.1-15.0).
(4) Four patients entered puberty during the first year of treatment.
(5) In girls and boys, the mean concentration of both gonadotropins increased with advancing puberty.
(6) Age at puberty (onset of cyclic progesterone concentrations) was greatest in heifers fed Diet 1 and lowest in heifers fed Diet 5.
(7) A 17-year-old boy who had been treated for insulin-dependent diabetes since age 2, and for coeliac disease since age 6, presented a major growth retardation (-6 SD), a delayed puberty and a hepatomegaly with excessive glycogen storage (Mauriac's syndrome).
(8) Adrenal androgens appear to be the major determinants of sebaceous gland activity during the prepubertal period and to be additive to another hormone or hormones during puberty.
(9) An investigation of the tissue distribution of CMB-2 showed that the puberty, CMB-2 is secreted into the rete testis and accumulates in the epididymis in high concentration.
(10) Seventeen of them showed a constitutional delay in growth and puberty, twenty-three suffered from growth-hormone deficiency (GHD) and eight had a suspected GHD as a result of pharmacological tests.
(11) This paper describes a case with symptomless enlarged submandibular glands, the bioptic findings which were suggesting the diagnosis of sialadenosis, the verification of the underlying disorder by child psychiatry, and the recuperation of the boy during puberty.
(12) Most of what is understood about precocious puberty in boys comes from boys with precocious puberty secondary to poorly controlled CAH.
(13) These and other data suggest that the sensitivity of the hypothalamic-pituitary "gonadostat" decreases at the onset of puberty.
(14) One possible explanation is that the bacteria associated with periodontal diseases cannot become established in great numbers prior to puberty.
(15) However, following puberty (i.e., by 60 days of age), the response in male rats was significantly greater than that observed in female rats.
(16) The development of signs of puberty and a growth spurt appearing at this late age clearly show the potential for maturation and growth once malnutrition is corrected.
(17) The progress of 108 children who were identified by the vision screening programme in school as having defective vision (excluding those with puberty onset myopia) was reviewed.
(18) Inhibin levels were high in prepubertal lambs (approximately 375 pM), but these levels were not sustained near the time of puberty (approximately 180 pM).
(19) Breast development is usually the first event of puberty and menarche virtually the last.
(20) It is hypothesized here that puberty in the rat is the consequence of the appearance of free, and therefore physiologically active, estrogen in the circulation.
Thymus
Definition:
(a.) Of, pertaining to, or designating, the thymus gland.
(n.) The thymus gland.
Example Sentences:
(1) Immunocompetence was also evident when the cells from thymectomized donors were first incubated with thymus extract for 1 hr and subsequently tested for reactivity.
(2) Release of 51Cr was apparently a function of immune thymus-derived lymphocytes (T cells) because it was abrogated by prior incubation of spleen cells with anti-thymus antiserum and complement but was undiminished by passage of spleen cells through nylon-wool columns.
(3) In 14 of the patients the imaging results were checked against the histological findings of a subsequent thymectomy, which revealed four thymomas and (with the exception of one normal thymus) hyperplastic changes in all the others.
(4) The bursa of Fabricius, thymus glands and spleen of chickens were also shown to express mRNA coding for ANP.
(5) The resulting cortexolone-Sepharose absorbed easily the cytosolic chick thymus glucocorticoid receptor.
(6) Thymus and spleen cells from such hypogammaglobulinaemic chickens were extracted with non-ionic detergents, acid urea, or combinations of urea and detergent, and the extracts were analysed for Ig by the inhibition assay.
(7) We previously found that transfected TNP-specific B cells undergo both Ca2+ signaling and desensitization upon interaction with the thymus-dependent Ag TNP-OVA.
(8) Tryptase also efficiently hydrolyzed histone H1 from rat thymus.
(9) However, the reactions of the thymus and spleen were different in this experiment, and further studies are necessary to evaluate the mechanism of these immune reactions.
(10) Although T cell tolerance to self antigens is primarily a reflection of clonal deletion in the thymus, recent evidence suggests that mature T cells are subject to negative regulation in the post-thymic environment: Extrathymic tolerance is the result of clonal anergy in some studies and T cell deletion in others.
(11) Identification of terminal deoxynucleotidyl transferase (TdT) positive cells in sites other than bone marrow, thymus, lymph nodes and peripheral blood is indicative of a TdT positive lymphoproliferative disease.
(12) Proliferative and cytollytical activity of lymphocytes was compared in lymphocyte alloimmunization of the spleen and intact thymus.
(13) We present a case of carcinoid heart disease and cardiac metastases discovered during a myocardial infarction in a 64 years-old woman who was treated for carcinod of the thymus.
(14) Skin grafts from Xenopus isogeneic to the donors of the MHC-incompatible larval and adult thymus implants are always tolerated by Tx hosts.
(15) The possibility that mammalian DNA topoisomerase II is an intracellular target which mediates drug-induced DNA breaks is supported by the following studies using 4'-(9-acridinylamino)methane-sulfon-m-anisidide (m-AMSA): (a) a single m-AMSA-dependent DNA cleavage activity copurified with calf thymus DNA topoisomerase II activity at all chromatographic steps of the enzyme purification; (b) m-AMSA-induced DNA cleavage by this purified activity resulted in the covalent attachment of protein to the 5'-ends of the DNA via a tyrosyl phosphate bond.
(16) The heterotransplantation of minced human fetal pituitaries into adult thymus-aplastic nude mice is described.
(17) The tryptic cores from H-2K and H-2D are regularly distinguishable from the thymus-leukemia antigens (TLA) by gel electrophoresis in one dimension.
(18) Each fraction was injected with either normal bone marrow cells or normal thymus cells with antigen into 650-R-irradiated hosts.
(19) mg and showed an incidence of 57% metastases to regional popliteal nodes and 5% metastases to thymus.
(20) Mouse thymus cells, educated to poly(tyrosyl,glutamyl)-polyDLalanyl--polylysyl [(T,G)-A--L], release an antigen-specific factor on brief culture in vitro.