(v. t. & i.) To gather into small folds or wrinkles; to contract into ridges and furrows; to corrugate; -- often with up; as, to pucker up the mouth.
(n.) A fold; a wrinkle; a collection of folds.
(n.) A state of perplexity or anxiety; confusion; bother; agitation.
Example Sentences:
(1) As in the protein sample, a tendency for the cis-proline residues to have the DOWN pucker was observed, but the effect was less pronounced.
(2) The ultrastructural findings of the macular pucker removed by vitreoretinal surgery are demonstrated.
(3) Sugar puckers and proton distances are very sensitive criteria to monitor molecular dynamics.
(4) Intranucleotide proton-proton distances combined with the knowledge of sugar puckers have been used to fix the glycosidic bond torsion angle (chi).
(5) High proliferative activities were found in 4 of 5 PVR membranes, in 9 of 14 PDR membranes, in 6 of 11 recurrent membranes after intraocular silicone oil tamponade, and in 2 of 6 macular pucker membranes.
(6) No "flips" to the opposite puckering for this ring were found in the simulations starting from the global minimum, although such a transition was observed for a trajectory initiated with one of the higher local minimum energy conformations.
(7) Thus, flexibility in psi as well as in omega and omega, and in the sugar pucker is indicated.
(8) These facts suggest that astrocytes play an important role in preretinal membrane formation in macular pucker.
(9) The free duplex adopts a regular right-handed B-type conformation in which all glycosidic bond angles are anti and all sugar puckers lie in the C2'-endo range.
(10) All cases occurred in eyes with existing retinal holes or tears, including eight cases of macular pucker after previous retinal detachment.
(11) The conformations of the terminal residues of helix I, which corresponds to bases (-1)-11 and 108-120 of native 5S RNA, are less well-determined, and their sugar puckers are intermediate between C2' and C3'-endo, on average.
(12) Different ester substituents affect 1,4-dihydropyridine ring puckering to a small extent in most cases.
(13) Scalar couplings from correlated experiments and interproton distances from NOESY experiments at short mixing times have been used to determine glycosidic angles, sugar puckers, and other conformational features.
(14) There appeared to be a possibility that this muscular thickening might give rise to the rectosigmoidal mucosal puckering often seen through a sigmoidoscope.
(15) Intranucleotide NOEs from the sugar protons H1', H2', and H3' to the base protons were used to determine the conformation of each nucleotide (puckers and glycosidic torsion angles).
(16) The most flexible conformational angles in the structure are the glycosidic angle and the sugar pucker.
(17) Of these, 89% of the cis-proline residues exhibit the DOWN pucker, while the trans-proline residues, on average, are about evenly distributed between the two forms.
(18) The folding of the polynucleotide chain is accomplished either solely by rotations around the P-O bonds or in concert with rotations around the nucleotide C4'-C5' bond with or without changes in the sugar ring pucker.
(19) Postoperative proliferative vitreoretinopathy occurred in six eyes (10%) and macular pucker in two (3%).
(20) The glycosidic torsional angle, chiCN = -28.4 degrees, is in the anti region; the sugar pucker is C(2')exo-C(3')endo in a nearly pure 32H twist; and the conformation of C(4')-C(5') is gauche-gauche.
Wrinkle
Definition:
(n.) A winkle.
(n.) A small ridge, prominence, or furrow formed by the shrinking or contraction of any smooth substance; a corrugation; a crease; a slight fold; as, wrinkle in the skin; a wrinkle in cloth.
(n.) hence, any roughness; unevenness.
(n.) A notion or fancy; a whim; as, to have a new wrinkle.
(v. t.) To contract into furrows and prominences; to make a wrinkle or wrinkles in; to corrugate; as, wrinkle the skin or the brow.
(v. t.) Hence, to make rough or uneven in any way.
(v. i.) To shrink into furrows and ridges.
Example Sentences:
(1) Transmission electron microscopy demonstrated that these blebs were devoid of organelles and microvilli; scanning electron microscopy revealed that the blebs were highly wrinkled and more numerous than were the projections observed in tissue from animals treated with testosterone alone, or in tissue from unoperated controls.
(2) However, patients can be taught how to retard the onset of wrinkles by avoiding unprotected sun exposure, unnecessary facial movements, and certain sleeping positions.
(3) Besides the rough, wrinkled, and brown or black surface of the fingertips, microwrinkles of the epidermis occur on the skin ridges, which have so far not been described.
(4) In fact, in some patients the lower-lid wrinkling appears far worse after fat removal.
(5) Substratum wrinkling was indicative of tension development and quantitated as percent of cells contracted.
(6) SMC also displayed several structurally detectable interactions with the fibrin substratum, such as organization of the gel by means of extension of numerous filamentous processes and contraction and wrinkling of the gel.
(7) A recipient cornea gradually developed wrinkling and opacification in Bowman's layer following an uneventful myopic epikeratoplasty.
(8) "But then a customer pointed out that our carpet was smoking and a chair was beginning to wrinkle in the heat, caused by the concentrated sun coming through the window."
(9) More than once, she replies to a question by wrinkling her nose and saying: “It’s all in the book.” Tempest can’t quite see why the breadth of her output – songs, poems, plays, a novel – is notable, because it’s all about writing and performance.
(10) Some intercalated sheaths had a wrinkled irregular configuration and some lacked a light-microscopically distinct myelin layer.
(11) Adhesions to the Gore-SM occurred at wrinkles in or at the edges of the membrane.
(12) During the course of the irradiation the animals develop permanent wrinkles on the exposed dorsal surface, which can be recorded in plastic impressions.
(13) The deflecting wrinkle is a well-known character state of the lower m2 and M1 of the human dentition, but there is little information regarding its presence in great apes.
(14) An algorithm is used to transform the number of wrinkles, recorded just before and 2.5 and 6 hr after the injection, into the intensity of the oedematous reaction.
(15) Fine wrinkling, coarse wrinkling, sallowness, looseness, and hyperpigmentation were significantly improved with tretinoin therapy.
(16) Kaeng Khoi virus was recovered from bedbugs (Stricticimex parvus and Cimex insuetus) and from suckling wrinkle-lipped bats (Tadarida plicata) collected in central Thailand.
(17) Hacked Off, which campaigns on behalf of victims of press intrusion for tighter press regulation, said this would help the government smooth out the wrinkles in the relevant clause added to the crime and courts bill, which attempts to define which publishers should be in or outside the regulator's remit.
(18) The percentage of cells showing a decrease of wrinkles was significantly higher (P less than 0.05 at 5 min and P less than 0.001 at 10 min) during the ANP-treated period than during the control period.
(19) Most dogs give a series of increasingly serious warning signs before they lose their tempers: lick their lips, blink, turn their heads away, curl their lip, lower their ears, wrinkle their foreheads, and if the dog that's annoying them doesn't get the message, they may growl or bare their teeth, and if that's still not enough it will be head and chest forward, muscles flexed, and bang, you've had it.
(20) Other specimens showed wrinkling of the outer layer that was seen later to peel off.