(1) Thus photosensitization using AISPc may be an effective method of purging marrow autografts in some cases of AML.
(2) Current investigations include the development of more effective cytoreductive regimens, use of recombinant hematopoietic growth factors, improvement of marrow purging techniques, and enhancement of cell-mediated anti-leukemic activity in patients receiving autologous marrow transplants.
(3) Direct detection of chromium in milk, using only argon as purge gas, was inferior.
(4) Indiana Indiana began to purge inactive voters in may 2014 by sending postcards to all registered voters.
(5) Sequential application of the two methods (immunorosette depletion with CD19 McAb followed by a complement lysis with CD9 and CD10 McAbs) led to superior results in causing a 4- to 5-log purging effect.
(6) Reduced caloric intake, a hallmark of both disorders, is manifested by self-induced starvation in anorexia and by binge eating and gastrointestinal purging in bulimia.
(7) Mafosfamide is presently used for the purging of bone marrow in autologous bone marrow transplantation in the treatment of acute leukemia.
(8) The two log difference in the surviving fraction of CFU-L and CFU-S after 120 min exposure to 42.5 degrees C suggests that hyperthermia ex vivo may be a suitable purging method for autologous bone marrow transplantation.
(9) There are already calls for large protests in Egypt this week demanding fair trials and retribution, as well as measures to purge former regime officials from political and economic life.
(10) Our data suggest that this new strategy shows potential for more effective ex vivo marrow purging in autologous marrow transplantation for acute lymphoblastic leukemia.
(11) In summary, laser light-induced photosensitization with MC540 has a selective cytotoxicity to leukemic cells; therefore, this procedure may be useful for purging neoplastic cells from autologous BM.
(12) Pretransplantation regimes were: total-body irradiation (TBI), 456; busulfan plus cyclophosphamide (BU-CY) 174; marrow purging with mafosfamide, 269 (corresponding to 26% of all patients in CR1 and 41% in CR2).
(13) Phase 1 studies of "in vivo purging" with a monovalent CD3 antibody (Clark et al., 1989), and also with a genetically engineered humanized IgG1 (CAMPATH-1H) (Hale et al., 1988b) suggest that these limitations can be overcome.
(14) Despite patient and disease heterogeneity, different sources of hemopoietic stem cells (allogeneic or autologous, bone marrow or blood), ex vivo purging of autografts, and different preparative regimens, some general recommendations can be made: (1) Allogeneic BMT should be reserved for patients under age 50, where transplant-related mortality can be expected not to exceed 30%; 40% will achieve CR with a 3-year relapse-free survival expectation of 70%, and (2) With autologous transplantation, low mortality under 10% and marked therapeutic benefit (greater than 30% CR, 80% overall survival at greater than 3 years) seem to be achievable mainly if performed when tumor bulk is low and standard doses of therapy are still effective.
(15) The transfusion purging leukocytes may diminish the occasions of alloimmunization.
(16) The Brotherhood's Libyan incarnation won only 10% of the vote in last year's congressional elections, but gained support with its campaign to mandate wholesale purges of Gaddafi-era officials.
(17) We feel that this system will prove valuable for monitoring ex vivo tumor removal in future clinical studies and should be considered for use in other purging trials.
(18) The quantitative determination of the efficacy of these purging methods is generally difficult.
(19) The government began aggressively purging the heads of cultural and academic institutions (a notable number of them Jewish and liberal intellectuals suspected of a “foreign” mindset) and installing in their stead true believers in the Magyar way.
(20) The result of our study in patients in second and third remission using in vitro purging of bone marrow with monoclonal antibodies PM-81 and AML2-23 are encouraging, as are the studies of purging with 4-HC.
Purger
Definition:
(n.) One who, or that which, purges or cleanses; especially, a cathartic medicine.
Example Sentences:
(1) The second investigation examined the discriminant validity of the Forbidden Food Survey by comparing the responses of three groups: bulimic binge-purgers, bulimic binge-eaters, and normals.
(2) As predicted from the anxiety model of bulimia, binge-purgers consistently reported stronger negative emotional responses to these foods than did the other groups.
(3) "Vomiters and purgers", on the other hand, were more outgoing in respect to personality.
(4) The first group consisted of subjects who had become emaciated solely because of dieting, food refusal and excessive exercising ("dieters"); the second of those who had used additional means to bring about weight loss such, as habitual vomiting and the abuse of purgatives ("vomiters and purgers").
(5) The anorectic patients were divided into subgroups of 19 abstainers and 46 vomiters and purgers.
(6) In the third experiment, bulimic binge-purgers were compared on Forbidden Food Survey responses to obese and normal subjects.
(7) It was found that the vomiters ate significantly more yet weighed less: the purgers ate less but weighed significantly more.
(8) The results indicate that the purgers control their weight by overall dietary restraint, not by the pharmacological action of the laxatives.
(9) Caloric requirements for weight gain in subgroups of anorectic patients (anorectic restrictors, anorectic binge-purgers) and weight maintenance in subgroups of anorectic and bulimic patients (bulimics with and without a prior history of anorexia nervosa) were studied in a total of 36 patients.
(10) From Father Gary's garden gate you get a view of where the paedophile-purgers of the Paulsgrove estate got into their stride.
(11) This excludes the possibility that F liver protein is a major histocompatibility complex molecule, and in turn raises a question about the uniqueness of F and certain other proteins as purgers of self-reactivity among T but not B cells.
(12) A sample (N = 114) of adolescent female binge-purgers were among the respondents to a nationwide survey on body-image.
(13) Both male and female purgers felt guiltier after eating large amounts of food, counted calories more often, dieted more frequently, and exercised less than nonpurgers.
(14) In contrast, purging was relatively ineffective, for despite smaller energy intakes, all the purgers were above (mean = 114 per cent)--and some markedly above--their MPMW.
(15) Bulimics and purgers were heavier, had greater triceps and subscapular skinfold thicknesses, and reported higher rates of drunkenness, marijuana use, cigarette use, and greater levels of depressive symptomatology.
(16) Binge-purgers also considered themselves to be more poorly psychosocially adjusted, with a reported childhood history of appearance-related conflicts.
(17) Relative to female controls (N = 114) who were matched on age, height and weight, binge-purgers evaluated their physical appearance, fitness and health much less favourably.
(18) Regardless of actual weight, binge-purgers more often distorted their body size as heavier than did controls, displayed more anxious preoccupation about their weight and weight gain and reported much more frequent eating restraint to lose weight.
(19) Again, binge purgers were found to respond with stronger negative responses than obese and normals.