(1) Thus photosensitization using AISPc may be an effective method of purging marrow autografts in some cases of AML.
(2) Current investigations include the development of more effective cytoreductive regimens, use of recombinant hematopoietic growth factors, improvement of marrow purging techniques, and enhancement of cell-mediated anti-leukemic activity in patients receiving autologous marrow transplants.
(3) Direct detection of chromium in milk, using only argon as purge gas, was inferior.
(4) Indiana Indiana began to purge inactive voters in may 2014 by sending postcards to all registered voters.
(5) Sequential application of the two methods (immunorosette depletion with CD19 McAb followed by a complement lysis with CD9 and CD10 McAbs) led to superior results in causing a 4- to 5-log purging effect.
(6) Reduced caloric intake, a hallmark of both disorders, is manifested by self-induced starvation in anorexia and by binge eating and gastrointestinal purging in bulimia.
(7) Mafosfamide is presently used for the purging of bone marrow in autologous bone marrow transplantation in the treatment of acute leukemia.
(8) The two log difference in the surviving fraction of CFU-L and CFU-S after 120 min exposure to 42.5 degrees C suggests that hyperthermia ex vivo may be a suitable purging method for autologous bone marrow transplantation.
(9) There are already calls for large protests in Egypt this week demanding fair trials and retribution, as well as measures to purge former regime officials from political and economic life.
(10) Our data suggest that this new strategy shows potential for more effective ex vivo marrow purging in autologous marrow transplantation for acute lymphoblastic leukemia.
(11) In summary, laser light-induced photosensitization with MC540 has a selective cytotoxicity to leukemic cells; therefore, this procedure may be useful for purging neoplastic cells from autologous BM.
(12) Pretransplantation regimes were: total-body irradiation (TBI), 456; busulfan plus cyclophosphamide (BU-CY) 174; marrow purging with mafosfamide, 269 (corresponding to 26% of all patients in CR1 and 41% in CR2).
(13) Phase 1 studies of "in vivo purging" with a monovalent CD3 antibody (Clark et al., 1989), and also with a genetically engineered humanized IgG1 (CAMPATH-1H) (Hale et al., 1988b) suggest that these limitations can be overcome.
(14) Despite patient and disease heterogeneity, different sources of hemopoietic stem cells (allogeneic or autologous, bone marrow or blood), ex vivo purging of autografts, and different preparative regimens, some general recommendations can be made: (1) Allogeneic BMT should be reserved for patients under age 50, where transplant-related mortality can be expected not to exceed 30%; 40% will achieve CR with a 3-year relapse-free survival expectation of 70%, and (2) With autologous transplantation, low mortality under 10% and marked therapeutic benefit (greater than 30% CR, 80% overall survival at greater than 3 years) seem to be achievable mainly if performed when tumor bulk is low and standard doses of therapy are still effective.
(15) The transfusion purging leukocytes may diminish the occasions of alloimmunization.
(16) The Brotherhood's Libyan incarnation won only 10% of the vote in last year's congressional elections, but gained support with its campaign to mandate wholesale purges of Gaddafi-era officials.
(17) We feel that this system will prove valuable for monitoring ex vivo tumor removal in future clinical studies and should be considered for use in other purging trials.
(18) The quantitative determination of the efficacy of these purging methods is generally difficult.
(19) The government began aggressively purging the heads of cultural and academic institutions (a notable number of them Jewish and liberal intellectuals suspected of a “foreign” mindset) and installing in their stead true believers in the Magyar way.
(20) The result of our study in patients in second and third remission using in vitro purging of bone marrow with monoclonal antibodies PM-81 and AML2-23 are encouraging, as are the studies of purging with 4-HC.
Purred
Definition:
(imp. & p. p.) of Pur
Example Sentences:
(1) No correlation between PUR, platelet survival, platelet function and the clinical situation could be assessed.
(2) The sequence of markers in the corresponding segment (mel to purA; 91.5 to 93.5 min) of the E. coli linkage map was shown to be mel--aspA--mop(groE)--ampA--frdA--pur A.
(3) Two types of repetitive DNA elements are located within the PAI-1 structural gene and flanking DNAs: we have found 12 Alu elements and 5 repeats of a long poly (Pur) element.
(4) These things happen, it all comes together and a team suddenly starts purring; we hit five in about 10 minutes and, with Jimmy [Greaves] in that groove, we'd have beaten any team anywhere.
(5) Pur repressor bound specifically to purF operator DNA as determined by gel retardation and DNase I footprinting assays.
(6) It is concluded that: PUR, but not BAC, is a useful pharmacological tool for the aminopeptidase inhibition and for activation of enkephalinergic neurons; aminopeptidases are concerned with activities of opioid peptides.
(7) Facebook Twitter Pinterest David Cameron tells Michael Bloomberg ‘the Queen purred’ Buckingham Palace declined to comment on the discussions between Geidt and Heywood.
(8) Before a ferociously red crowd, in which the Australian fans, scattered throughout the stadium in little blobs of yellow, struggled to assert themselves in any meaningful way, the Chileans started with their customary disregard for defence, a line of five attackers purring forward with gushing, almost smug intent.
(9) The order of the markers was hom-1-thr-1-his-1-(gly-1 or gly-2)-pur-1-pur-2.
(10) Nicola Sturgeon could be sat in that castle now – we know she had her eye on it – it was a damn close-run thing.” Royal circles found particularly offensive Cameron’s portrayal of the Queen as having “purred down the line” when he telephoned her to tell her Scotland had voted against independence.
(11) The dominance of the referendum explains why a relieved Cameron told the former New York mayor Michael Bloomberg, in an overheard conversation days after the referendum, that the Queen had “ purred down the line ” when he told her the result.
(12) Furthermore, Pur-1 is able to activate an intact insulin promoter in HeLa cells, where it is normally inactive.
(13) The concentration of PPRibP has been examined in the rat adrenal gland at various times after induction of diabetes with STZ, in view of the key role it plays in the synthesis of Purs and Pyrs.
(14) Mutations in this group have previously been shown to be pleiotropic, affecting not only ras but also two other genetic entities, gua 1 and pur 1, which yield auxotrophic mutations.--The eight new mutations have been characterized phenotypically in double heterozygotes with gua 1, pur 1 and ras mutations.
(15) Washington is positively purring with pleasure over Abe's tougher stance.
(16) He tossed Shakespeare into a modern-day, thinly veiled Miami in the electrifying Romeo + Juliet and sent Nicole Kidman wafting, purring and simpering through bohemian Paris in Moulin Rouge!
(17) Puromycin aminonucleoside, an analog of PUR with no inhibitory action on protein synthesis, had no effect.
(18) Exogenously supplied histidine (that blocks conversion of AMP to guanine nucleotides) does not reduce the growth rate of the strain of pur apt genotype on adenosine as the sole purine source.
(19) The mutation, called rer, is located between arg B and pur D loci.
(20) PUR induced the dose-related analgesic effect abolished by NAL and increased the level of ENK in the striatum.