(n.) A disease characterized by livid spots on the skin from extravasated blood, with loss of muscular strength, pain in the limbs, and mental dejection; the purples.
(n.) A genus of marine gastropods, usually having a rough and thick shell. Some species yield a purple dye.
Example Sentences:
(1) Purpura fulminans is the cutaneous manifestation of acute activation of the clotting mechanism resulting in massive hemorrhage due to an intravascular consumption coagulopathy.
(2) A close correlation between purpuric reaction and drugs was observed in seven cases of chronic pigmented purpura.
(3) The criteria selected by a classification tree method were similar: palpable purpura, age less than or equal to 20 years at disease onset, biopsy showing granulocytes around arterioles or venules, and gastrointestinal bleeding.
(4) The association of idiopathic thrombocytopenic purpura (ITP) and pregnancy is of special therapeutic significance because it increases the risk to mother and infant during labor.
(5) Two cases with brain purpura following Gram-negative septicaemia were examined morphologically and immunohistochemically.
(6) Chronic idiopathic thrombocytopenic purpura (ITP) is an autoimmune disorder in which the abnormality in cellular immunity has remained only vaguely defined.
(7) Idiopathic thrombocytopenic purpura (ITP) is more frequently seen in young females than in any other age or sex group.
(8) An eight-day-old girl suffered from purpura fulminans at her four extremities, skull, bladder, ovary and vagina.
(9) Sera from 24 children with Henoch-Schönlein purpura (HSP) and 25 controls were tested for rheumatoid factor (RF) of various isotypes.
(10) The discoveries that in Graves' disease and myasthenia gravis there are IgG antibodies directed against receptors sites are examples of such developments, while "ikiopathic" thrombocytopenic purpura is now accepted as immunological owing to its behaviour during pregnancy.
(11) We attempted to search for any specific change in the immune system during the onset of childhood acute immune thrombocytopenic purpura (ITP) in order to clarify the pathophysiology of acute ITP by examining the lymphocyte subset, lymphocyte blastogenic response, serum complements, and immunoglobulins in 18 patients with childhood acute ITP and 18 controls (control values after normalization).
(12) The hematoma resulted from intraparenchymal bleeding due to Henoch-Schönlein purpura.
(13) Verotoxin-producing E. coli (most frequently E. coli O157) have been implicated in the pathogenesis of diarrhea, hemorrhagic colitis, hemolytic uremic syndrome and thrombotic thrombocytopenic purpura.
(14) The action of intravenous immunoglobulins (IVIG) in autoimmune diseases, especially in idiopathic thrombocytic purpura seems to be due to Fc-receptor blockade and immunomodifying qualities.
(15) Newborn infants with congenital homozygous protein C deficiency develop catastrophic thrombosis (purpura fulminans) and will not survive beyond the neonatal period without protein C replacement.
(16) The onset of purpura in this patient was during the incubation of rubella before the initiation of immune response, suggesting that in some patients the mechanism of platelet damage in ITP associated with rubella is through a direct effect of the virus, rather than by circulating antibodies.
(17) At autopsy there were scattered purpura on the skin, and the muscles were atrophic and yellowish-grey in color.
(18) 18 patients with proven autoimmune thrombocytopenic purpura (ATP) (group A) were screened for human lymphocyte antigens (HLA) and compared with 13 patients with secondary thrombocytopenic purpura (group B).
(19) Five patients with post-transfusion purpura (four due to Zw(a), one presumably due to HLA antibodies) were treated with intravenous immunoglobulin (IgG) at doses of 0.4 g per kg body weight.
(20) We have investigated the methods for the maintenance of a pregnancy in a patient with thrombotic thrombocytopenic purpura (TTP), said condition, since 1984, having been controlled by a plasma infusion every 3 to 4 weeks.
Skin
Definition:
(n.) The external membranous integument of an animal.
(n.) The hide of an animal, separated from the body, whether green, dry, or tanned; especially, that of a small animal, as a calf, sheep, or goat.
(n.) A vessel made of skin, used for holding liquids. See Bottle, 1.
(n.) The bark or husk of a plant or fruit; the exterior coat of fruits and plants.
(n.) That part of a sail, when furled, which remains on the outside and covers the whole.
(n.) The covering, as of planking or iron plates, outside the framing, forming the sides and bottom of a vessel; the shell; also, a lining inside the framing.
(v. t.) To strip off the skin or hide of; to flay; to peel; as, to skin an animal.
(v. t.) To cover with skin, or as with skin; hence, to cover superficially.
(v. t.) To strip of money or property; to cheat.
(v. i.) To become covered with skin; as, a wound skins over.
(v. i.) To produce, in recitation, examination, etc., the work of another for one's own, or to use in such exercise cribs, memeoranda, etc., which are prohibited.
Example Sentences:
(1) The catheter must be meticulously fixed to the skin to avoid its movement.
(2) Elements in the skin therefore seemed to enhance nerve regeneration and function.
(3) This is a fascinating possibility for solving the skin shortage problem especially in burn cases.
(4) Blood flow decreased immediately after skin expansion in areas over the tissue expander on days 0 and 1 and returned to baseline levels within 24 hours.
(5) These findings suggest that clonidine transdermal disks lower blood pressure in hypertensive patients, but produce local skin lesions and general side effects.
(6) Currently, photodynamic therapy is under FDA-approved clinical investigational trials in the treatment of tumors of the skin, bronchus, esophagus, bladder, head and neck, and of gynecologic and ocular tumors.
(7) Immunofluorescent staining for HLA-DR showed dermal positivity in 12 of 13 involved- and 9 of 13 uninvolved-skin biopsy specimens from scleroderma patients, compared with only 1 of 10 controls.
(8) Blood flow was measured in leg and torso skin of conscious or anesthetized sheep by using 15-micron radioactive microspheres (Qm) and the 133Xe washout method (QXe).
(9) A similar interference colour appeared after incubating sections of rat skin with chymase.
(10) Peptides from this region bind to actin, act as mixed inhibitors of the actin-stimulated S1 Mg2(+)-ATPase, and influence the contractile force developed in skinned fibres, whereas peptides flanking this sequence are without effect in our test systems.
(11) This study was designed to examine the effect of the storage configuration of skin and the ratio of tissue-to-storage medium on the viability of skin stored under refrigeration.
(12) Somatostatin-like immunoreactivity has been found to occur in nerve terminals and fibres of the normal human skin using immunohistochemistry.
(13) We recommend analysing the urine for porphyrins in HIV-positive patients who have chronic photosensitivity of the skin.
(14) We investigated the incidence of skin cancer among patients who received high doses of PUVA to see whether such incidence increased.
(15) Attachment of the graft to the wound is similar with and without the addition of human basic fibroblast growth factor, a potent angiogenic agent, to the skin replacement before graft placement on wounds.
(16) In order to develop a sampling strategy and a method for analyzing the circadian body temperature pattern, we monitored estimates of the temperature in four ways using rectal, oral, axillary and deep body temperature from the skin surface every hour for 72 consecutive hours in 10 normal control subjects.
(17) It was shown that the antibiotic had low acute toxicity, did not cumulate and had no skin-irritating effect.
(18) Compliance during dehydration was 7.6 and 12.5% change in IFV per millimeter Hg fall in IFP (micropipettes) in skin and muscle, respectively, whereas compliance in subcutis based on perforated capsule pressure was 2.0% change in IFV per millimeter Hg.
(19) For the second propositus, a woman presenting with abdominal and psychiatric manifestations, the age of onset was 38 years; the acute attack had no recognizable cause; she had mild skin lesions and initially was incorrectly diagnosed as intermittent acute porphyria; the diagnosis of variegate porphyria was only established at the age of 50 years.
(20) 14 patients with painful neuroma, skin hyperesthesia or neuralgic rest pain were followed up (mean 20 months) after excision of skin and scar, neurolysis and coverage with pedicled or free flaps.