(n.) The low murmuring sound made by a cat; pur. See Pur.
Example Sentences:
(1) Expression of glyA, encoding serine hydroxymethyltransferase activity, was elevated in a purR mutant compared with a wild-type strain.
(2) A bulldozer on rail wheels purrs up on the other line and begins pawing at the stones.
(3) At the place where adorable meets obnoxious and the purr becomes a shriek, Leslie Mann is waiting to unload a howitzer of funny in your face.
(4) Nitrogen control was found to be mediated by the glnLG gene products, and purine repression required a functional purR gene product.
(5) Though I could have sworn that you did actually purr,” Dave recalled.
(6) AMP but not GMP is needed for binding, and purR mutants are deficient in the binding substance.
(7) The PurR protein bound specifically to a DNA fragment carrying the glyA control region, as determined by gel retardation.
(8) Cross pathway regulation of pyrC by PurR may provide one mechanism to coordinate synthesis of purine and pyrimidine nucleotides.
(9) "Oh, the lords absolutely love Justin," purrs one senior peer.
(10) Both operator constitutive and repressor type (purR) mutations have been identified.
(11) The purR product functions in the common control of several genetically distinct enzymes that participate before the formation of IMP.
(12) The regulation of the guanine operon is regulated by some other mechanism independent of purR.
(13) A highly conserved sequence in the promoter regions of these two genes is similar to the pur operator, which is the binding site for the purine repressor (PurR).
(14) Gene purB is regulated threefold by the purine pool and purR.
(15) The purEK operon is regulated by the purR gene product, and a purR regulatory-protein-binding site related to the sequences found in other pur loci was identified in the purEK operon control region.
(16) In the film, there is a killingly funny vignette in which Joshua McGuire’s Ruskin, who cannot pronounce his Rs, purrs with self-satisfaction at his own ideas – the critic who got the cream.
(17) Analysis of a purR-lacZ transcriptional fusion indicated that purR expression is autoregulated.
(18) Mutations that changed the binding sequence toward the consensus sequence had no significant effect on either PurR binding or purine-mediated repression.
(19) Site-directed mutagenesis was used to change the PurR binding site in the control region of a glyA-lac gene fusion.
(20) Two independent purR mutations were isolated which abolished repression of purF and purF-lacZ.
Rumble
Definition:
(v. i.) To make a low, heavy, continued sound; as, the thunder rumbles at a distance.
(v. i.) To murmur; to ripple.
(n.) A noisy report; rumor.
(n.) A low, heavy, continuous sound like that made by heavy wagons or the reverberation of thunder; a confused noise; as, the rumble of a railroad train.
(n.) A seat for servants, behind the body of a carriage.
(n.) A rotating cask or box in which small articles are smoothed or polished by friction against each other.
(v. t.) To cause to pass through a rumble, or shaking machine. See Rumble, n., 4.
Example Sentences:
(1) But I know the full story and it’s a bit different from what people see.” The full story is heavy on the extremes of emotion and as the man who took a stricken but much-loved club away from its community, Winkelman knows that his part is that of villain; the war of words will rumble on.
(2) In two exceptional patients with a prolonged PR interval, this apical sound was separated from a presystolic rumble that occurred during an accelerated phase of mitral inflow or at the A wave of mitral valve echograms.
(3) So little wonder that the spectacle of five safety incidents in a week – however minor – could trigger rumblings of distrust from a nervous public.
(4) As soon as the feed-in tariff was removed, that position looked very different.” What’s more, Rumble believes that solar energy was just a few years away from being cheap enough not to require government support to grow.
(5) The students said they were told in London that a journalist would accompany them and that they risked deportation or detention if they were rumbled.
(6) It was here in 1974 that the heavyweights fought the Rumble in the Jungle under the gaze of dictator Mobutu Sese Seko .
(7) The LV dimension was significantly decreased in HCM with rumble as compared with those of HCM without rumble and the normal subjects.
(8) It sounds like the rumblings of a typical North Korean purge.
(9) Sir Richard Dalton, former UK ambassador to Iran "Iran seems to have been tipped off and come clean because it knew it was about to be rumbled.
(10) "Fortunately Denmark seem to have rumbled this sneaky Dutch trick just in time to bench him... " 1 min: Denmark set the game in motion ... 2 min: Already the game has settled into the pattern we all foresaw, with Holland staking out the full width of the pitch and stroking the ball around deliberately.
(11) Rumblings of discontent had been circulating for months with the two clashing over player recruitment following a summer of inexplicable inactivity at Bloomfield Road , and the point of no return appeared to be reached when then-Burton boss Gary Rowett was openly offered the job in September.
(12) 1 Muhammad Ali's 'rope-a-dope' Ali's "rope-a-dope" plan for 1974's Rumble in the Jungle – his fight against unbeaten George Foreman for the world heavyweight title – was one of the riskiest strategies ever seen in boxing.
(13) On cardiac examination, a pansystolic bruit and a diastolic rumble were audible at the tricuspid focus.
(14) Less noticed, because less obviously political, are current intellectual rumblings, of which French economist Thomas Piketty's Capital in the Twenty-First Century , a withering indictment of growing inequality, is the latest manifestation.
(15) All that changed on China’s “Black Monday” last week, when the stock market sell-off that had been rumbling along for weeks turned into a rout.
(16) There are rumblings that Goldman and UBS should go without some of their fees if it is found they got the valuation wrong.
(17) Turkish police appeared uneasy at the size of the crowd gathered near a fragile border fence and fired teargas grenades to disperse them, adding the crack of smaller explosions to the rumbling of the Isis advance.
(18) Factors necessary for the production of a diastolic rumble appear to include central flow, a flexible stent, and the presence of biologic material.
(19) Discontent has been rumbling at New York fashion week since 2010, when the official catwalks were relocated from the more intimate Bryant Park space to the Lincoln Centre.
(20) Perhaps because few of us know what a gene actually does, the debate about whether we are a product of our DNA or our environment rumbles on.