(a.) Commonly thought or deemed; supposed; reputed; as, the putative father of a child.
Example Sentences:
(1) We report a series of experiments designed to determine if agents and conditions that have been reported to alter sodium reabsorption, Na-K-ATPase activity or cellular structure in the rat distal nephron might also regulate the density or affinity of binding of 3H-metolazone to the putative thiazide receptor in the distal nephron.
(2) The mboIIR gene specifies a protein of 416 amino acids (MW: 48,617) while the mboIIM gene codes for a putative 260-residue polypeptide (MW: 30,077).
(3) This gene, termed cbbE', codes for a putative surface protein of approximately 55 kDa, termed the E' protein.
(4) On the basis of primary sequence homology with other known Pseudomonas lipases, a number of putative active site residues located in conserved areas were found.
(5) The nature of the putative autoantigen in Graves' ophthalmopathy (Go) remains an enigma but the sequence similarity between thyroglobulin (Tg) and acetylcholinesterase (ACHE) provides a rationale for epitopes which are common to the thyroid gland and the eye orbit.
(6) In fact, the distribution of [3H]oleate between plasma membranes and unilamellar vesicles of lipids extracted from these membranes was in favor of the lipids, indicating the absence of a detectable amount of binding to a putative fatty acid binding protein in plasma membranes.
(7) The NM23-Hl gene is a putative tumor suppressor gene that may be important in the metastasic process.
(8) Mixing experiments were performed to test the putative inhibitory effects of allotype-suppressed spleen cells from the first adoptive transfer (stage I) on the antibody response of normal spleen cells in a second adoptive transfer (stage II).
(9) The peptides, which were synthesized using a FMOC solid phase procedure and purified by HPLC, consisted of residues 6-25 from the putative aqueous domain, residues 22-35, which overlaps the putative aqueous and transmembrane domains, and residues 1-38 and 1-40 representing nearly the full length of beta-AP.
(10) The concentrations of anesthetics having this effect on the putative Ca2+ channel were between 0.0026 and 0.078 MAC equivalents for each agent, and these concentrations are much lower than the anesthetic concentrations affecting Ca2+ uptake.
(11) Since the discovery of peptides in hypophysis and brain, several classes of these peptides have been tested on their putative antidepressive properties.
(12) A putative pineal metabolite, 5-methoxyindole-3-acetic acid, was quantified in human urine by a gas chromatographic-mass spectrometric method.
(13) The nucleoprotein gene is located proximal to the 3' end of the genome and is preceeded by a putative leader sequence.
(14) The polypeptide encoded by this thyroid-specific transcript consisted of a 398-amino acid residue amino-terminal segment, constituting a putative extracellular domain, connected to a 346-residue carboxyl-terminal domain that contained seven putative transmembrane segments.
(15) It appears that irrespective of the elucidation of the nature of the putative aetiological factor (presumed to be viral) in MS, the arrest and reversal of T cell-related events within the CNS in this devastating condition represent feasible goals and should remain a major target for some time to come.
(16) In addition, the postulated personality for PD may predispose to hard work, perspiration, and increased exposure to putative trace elements in the water supply.
(17) The sequence of the rep control region was determined, and putative regulatory sequences were identified; no evidence for autoregulation of expression was obtained.
(18) Analysis of the 5' region of the gene reveals several putative transcription factor binding sites which may be important for the complex transcriptional regulation of this gene.
(19) In a direct test of the hypothesis that the M2 coat protein of influenza A can function as a proton translocator, we incorporated a synthetic peptide containing its putative transmembrane domain into voltage-clamped planar lipid bilayers.
(20) In order to identify putative protein splicing factors associated with the 200S InRNP particles, a panel of monoclonal antibodies directed against these particles were screened for their ability to inhibit splicing of pre-mRNA in vitro.
Supposition
Definition:
(n.) The act of supposing, laying down, imagining, or considering as true or existing, what is known not to be true, or what is not proved.
(n.) That which is supposed; hypothesis; conjecture; surmise; opinion or belief without sufficient evidence.
Example Sentences:
(1) Utilization of the immunoglobulin system is based upon the supposition that in lymphoid neoplasms with clonal origin either all or none of the tumor cells should have surface-associated IgM and kappa-reactivities.
(2) The functional role of the retino-thalamo-telencephalic system in the visual integration in birds is discussed and a supposition is advanced on possibility to compare the Wulst region with striatal and frontal visual areas of the mammalian cortex.
(3) Pharmacological analysis permitted a supposition to be made that there were two receptor systems in the sensory nerve endings of the cornea; these systems were in reciprocal inhibitory relations; due to this their regular influence on the processes of excitation and inhibition is effected in the sensory nerve ending.
(4) Gel filtration chromatography on G-200 Sephadex confirmed this supposition and demonstrated that the abnormal globin chain polymerized with itself as well as with other globin chains.
(5) An analysis of concentration dependence of binding these ions with human serum albumin confirmed earlier supposition about the nature of the binding sites of Mn2+ ions with HSA.
(6) The present results are consistent with the supposition that the high-affinity site for ATP on the holoenzyme is congruent with the phosphotransferase site of the catalytic subunit.
(7) A supposition is advanced that such a difference in duration is determined primarily by properties of these neurons.
(8) On the basis of a study of the palmomental reflex in 100 children (from new born to 3 years) and in 73 adult patients with organic lesions of the CNS the author makes a supposition of a connection between its appearance and a lesion of the caudate nucleus.
(9) These results confirm our earlier supposition that the additional high frequency internal motions of the thick filaments isolated from striated muscle of Limulus are related to the energy dependent, active cross-bridge motions.
(10) Our own data and the meagre results of other studies support the supposition that it is not the absolute time-lapse which has prognostic significance but the qualified medical assistance provided within a critical, individual, but extremely variable time-span.
(11) These data permit a supposition that reduction of lipid peroxidation is one of the pathogenetic mechanisms of delayed type hypersensitivity, and that lipid peroxidation enhancement in the skin by iron sulfate electrophoresis is one of the possible mechanisms of suppressing allergic contact dermatitis.
(12) In the second case, only subjective suppositions are possible.
(13) The supposition that these were B-lymphocytes was supported by analogous morphometric examination on lymphocytes obtained from the thymus and bursa Fabricius of newly shelled chickens and it was established that this number in the bursa was more than twice larger.
(14) These findings document yet another "inappropriate" pattern of intermediate filament immunoreactivity in normal and neoplastic human cells, and contradict the widely held supposition that the expression of GFAP is restricted to cells of glial origin.
(15) The increase in the rate constant for potassium loss in the presence of ouabain favours this supposition.
(16) The results are consistent with the supposition that, on application of a continuous moderate stress, tension induces formation and pressure resorption of bone.
(17) These findings, when viewed from the standpoint of the accepted concept that optimum stimulation to the otolith organ constitutes the shearing force, account well for the supposition that forward-and-backward movement stimulates both the sacculi and utriculi, while up-and-down movement stimulates the sacculi alone.
(18) The dominance of males with the ratio of 2:1, manifestation of damage not only in sibs, but also in other relatives, and the absence of consanguineous couples testify in favour of this supposition.
(19) The first reported case of lissencephaly resulting from a consanguinous union strengthens the supposition that in some cases, it is transmitted as an autosomal recessive trait.
(20) The supposition of Pándy has proved to be entirely erroneous.