(a.) Related to, or formed from, pyridin or its homologues; as, the pyridic bases.
Example Sentences:
(1) Preliminary experiments using a hexadentate pyrid-2-one, CP130, show that this causes significant 59Fe excretion both when given intraperitoneally or orally.
(2) 1-Ethyl-2-methyl-3-hydroxy-pyrid-4-one (EMHP), a low molecular weight iron chelator that is soluble in hydrocarbon solvents and presumably in lipids, was studied for in vitro inhibition of radical-mediated peroxidation of DNA.
(3) The major metabolite formed was 4-(2-amino-1-methylimidazo[4,5-b]pyrid-6-yl)phenyl sulfate (4'-PhIP sulfate).
(4) The binding profiles of the muscarine receptor antagonists atropine, 11-[2-[dimethylamino)methyl)-1-piperidinyl)acetyl)-5,11-dihydro-6H-pyrid o(2,3- b) (1,4)benzodiazepine-6-one (AF-DX 116), pirenzepine, and 4-diphenylacetoxy-N-methylpiperidine methiobromide (4-DAMP) in both tissues were compared with binding data from other tissues, representative for different muscarinic binding site subtypes.
(5) In addition, 3-(1,2,5,6-tetrahydropyrid-4-yl)pyrrolo[3,2-b]pyrid-5-one (CP 93, 129), 7-trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrolo[1,2-a]quinox ali ne (CGS 12066B), 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI), 3-chlorophenylbiguanide (mCPBG), NAN-190, nisoxetine, zacopride, 1-PP, (+)-N-allylnormetazocine ((+)-NANM), and N-methyl-1-(3,4-methylenedioxyphenyl)-2-aminopropane (MDMA) were analyzed in tests of stimulus generalization.
(6) Piperidinoalkyl-, morpholinoalkyl- or [(pyrid-2-yl)methylthio]alkyl-substituents were introduced into position 2 of the essential histamine structure.
(7) Acetylation of 17 provided 4-amino-3-fluoro-1-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-2(1H)-pyrid inone (29).
(8) Realizing the extent of the problem, the Regional Office for Europe organized two consultations to develop drinking water quality guidelines for the following 11 herbicides most commonly used in Italy: alachlor, metolachlor, pyridate, atrazine, molinate, simazine, bentazon, pendimethalin, trifluralin, MCPA and propanil.
(9) On the other hand, pretreatment of the rats with nicotine had no significant effect on the methylation of DNA by NNK nor on the elimination constants of NNK and its major metabolite 4-(methylnitrosamino)-1-(3-pyridly)-1-butanol.
(10) Product-inhibition studies, however, indicated that a compulsory-order mechanism was followed in which NADPH bound before pyridine-3-aldehyde with a ternary complex being formed and the release of pyrid-3-ylcarbinol before NADP+.
(11) At all doses, the major urinary metabolite was identified as 4'-(2-amino-1-methylimidazo[4,5-b]pyrid-6-yl)phenyl sulfate and this metabolite comprised approximately 5% of the dose.
(12) A cephalosporin, (6R,7R)-7-[(2R)-2-hydroxy-2-phenylacetamido]-3-(pyrid-2-yl-N-oxide) thiomethylceph-3-em-4-carboxylic acid (MCO), that could lead to a novel approach to the problem of beta-lactamase destruction is described.
(13) Torasemide (1-isopropyl-(4-(3-methylphenylamino)pyrid-3-yl)urea) is a new diuretic.
(14) The synthesis and in vitro and in vivo characteristics of 3-(1,2,5,6-tetrahydropyrid-4-yl)pyrrolo[3,2-b]pyrid-5-one (1, CP-93,129) are described.
(15) However, the ferric iron chelators 1,2-dimethyl-3-hydroxy-pyrid-4-one (L1) and pyridoxal isonicotinoyl hydrazone (PIH) were only weakly inhibitory.
(16) Derivatives of 2-amino-3-nitropyridine (4; see Table I for structures) and 2-amino-3-nitro-1H-pyrid-6-one (5), conceived as cyclic 'urea equivalents' of histamine H2-receptor antagonists, were prepared.
(17) Compounds I, II and III were identified as 5'-O-(beta-D-galactopyranosyl)-pyridoxine, 4'-O-(beta-D-galactopyranosyl)-pyridoxine, and 4'-O-(beta-D-galactopyranosyl-(1----4)-beta-D-galactopyranosyl)-pyrid oxi ne, respectively, on the basis of the various experimental results, viz., ultraviolet, infra-red, 1H-NMR, and 13C-NMR spectra, products by hydrolysis with acid and with alpha- and beta-galactosidases, migration on paper electrophoresis, and Gibbs reaction in the presence and absence of boric acid.
(18) Carbapenems with 2-substituents containing pyrid-3-yl and -4-yl moieties could be labeled by this method, but those containing a pyrid-2-yl group could not.
(19) 3-Amino-5-(4-pyridinyl)-1,2-dihydro-pyrid-2-one (1) is an amphoteric compound and forms one crystalline sodium salt and two hydrochlorides.
(20) In experiments on anesthetized cats with acute occlusion of the coronary artery followed by its reperfusion antihypoxants piracetam, lithium hydroxybutyrate and pyrid oxynyl-glyoxylate (glyo-6) were shown to stabilize the contractile and pumping functions of the heart.
Pyritic
Definition:
(a.) Alt. of Pyritical
Example Sentences:
(1) The ultrastructure of rabbit tracheal epithelium was studied 2, 8 and 26 hours after termination of 8-hour inhalation of ground pyrite dust.
(2) Evidence for the direct utilization of the sulphur moiety of pyrite by Thiobacillus ferrooxidans was derived from the following observations: a.
(3) An aerobic facultative thermophilic bacterium was isolated from the ore of the Nikolaev copper-zinc-pyrite deposit in the Eastern Kazakhstan.
(4) A research study was carried out at a pyrite mine in Niccioleta, southern Tuscany, during the period 1980-1983 to investigate the possible effects of gaseous and particulate pollutants on the respiratory function of mine workers.
(5) Wistar rats were injected intratracheally with pyrite particles and after 6 and 12 mo, lungs were evaluated for histological changes.
(6) Pyrite particles persist in the cytoplasm of ciliated cells throughout the interval followed up.
(7) It is proposed that the energy-transducing system of the first cellular organism and its precursor was fueled by the oxidation of hydrogen sulfide and ferric sulfide to iron pyrites and two [H+] on the outside surface of a vesicle (the cell membrane), with the concomitant reduction of CO or CO2 on the interior.
(8) A technique was developed for measuring (14)CO(2) uptake by chemolithotrophic bacteria directly in pyritic materials associated with coal and coal refuse.
(9) The cycle is catalytic for pyrite formation and autocatalytic for its own multiplication.
(10) The presence of high concentrations of sulfate, iron, and hydrogen (acid) ions in drainage from coal mines and other areas containing waste pyritic materials is a serious water pollution problem.
(11) The effect of pyrite added to the waste materials before the beginning of leaching has also been examined.
(12) The aforementioned importance is related to the ability of the bacterium to oxidize reduced iron and sulfur, principally found in nature as pyrite (FeS2).
(13) The morphogenesis of Sulfobacillus thermosulfidooxidans BKM B-1269 was studied by electron microscopy at the vegetative stage of growth on a medium with pyrite as the source of energy.
(14) Three species of thermophilic archaebacteria of the genera Sulfolobus (Sulfolobus acidocaldarius and S. solfataricus) and Acidianus (Acidianus brierleyi) were tested for their ability to oxidize pyrite and to grow autotrophically on pyrite, to explore their potential for use in coal desulfurization.
(15) These include: lack of controls while mining is underway; catastrophic events, such as the collapse of a settling dam, lack of site specific understanding of pyrite oxidation processes, particularly those that are biologically enhanced; the need for adequate biological information on which to base decisions to meet biological information on which to base decisions to meet biological objectives.
(16) Ferric, sulfate, and hydrogen ions are produced from pyritic minerals associated with coal as a result of autotrophic bacterial metabolism.
(17) A cohort mortality study was conducted with regard to a pyrite mine located in central Italy.
(18) They were skillful dental surgeons and made prostheses from jade and turquoise and filled teeth with iron pyrite.
(19) Only A. brierleyi was able to oxidize and grow autotrophically on pyrite.
(20) For instance, gold mining in South Africa’s Witwatersrand Basin – on which Johannesburg’s economy was founded – has left 120 mines’ worth of pyrite tailings, containing 450,000 tonnes of uranium.