(1) It is found that, in contrast to most metallic materials yet in keeping with many ceramics, there are no distinct fracture morphologies in pyro-carbons which are characteristic of a specific mode of loading; fracture surfaces appear to be identical for both catastrophic and subcritical crack growth under either sustained or cyclic loading.
(2) Studies of a monoclonal IgA (lambda) protein with both cryo- and pyro-precipitability show that it belongs to the IgA2 subclass and is positive for the A2m(2) allotypic marker.
(3) Based on the assumption that amino acid residues which are critical for function are preferentially conserved, we predict from the sequence that glycine residue 15 rather than residue 12 is important for (pyro)phosphate binding.
(4) The Michaelis constant, Km, for hydrolysis of pyro-Glu-Pro-Arg-p-nitroanilide by thrombin was increased 1.8-fold, from 130 to 230 microM, as a result of the binding of protein Z and the Km for H-Val-Leu-Arg-p-nitroanilide 1.4-fold, from 390 to 560 microM.
(5) No cross-reactivity of (3--10) LH-RH, pyro-His-Trp-SerOMe and TRH was recorded with LH-RH, whereas slight cross-reaction was observed for (Lys8) LH-RH and (Ala4) LH-RH showed marked cross-reaction.
(6) The ratio of rates of production of pyro to isopyro derivatives is 2:1 throughout.
(7) However, the cytochrome c reduction by the electron transport system was inhibited in the presence of inorganic (pyro)phosphate.
(8) The activities of the pyro- and orthophosphate fractions were used to calculate the amount of acidic calcium phosphate present in the nascent mineral.
(9) (Pyro)-Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 appears to account for most of all of the LHRH and FSHRH activity found.
(10) From the crude venom we have isolated several pyro-glutamate containing peptides, two of which are relatively good inhibitors of the toxins.
(11) The structure of pGlu-Phe-Pro (where p-indicates pyro-) amide was confirmed by fast atom bombardment mass spectrometry.
(12) More than 150 hypothalamic fractions were reassayed for luteinizing hormone-releasing hormone (LHRH) and follicle stimulating hormone-releasing hormone (FSHRH) activities in search for LHRH and FSHRH which differ from the decapeptide (pyro)Glu-His-Trp-Ser-Try-Gly-Leu-Arg-Pro-Gly-NH2 (I).
(13) Exophthalmos has been induced in carp by injecting thyrotropin releasing hormone (TRH) (PYRO-glutamyl-histidyl-prolinamide) into the coelom.
(14) Modifications of the Komnick potassium (pyro)antimonate precipitation method have been widely used for the subcellular localization of a variety of cations.
(15) The localization of pyro-antimonate-precipitable Ca2+ in the undecalcified femur and calvaria of neonatal rats was examined.
(16) Homogenates of brain, pituitary, liver, lung, ovary, and testes were incubated with [pyro Glu1-3,4-3H]luteinizing hormone-releasing hormone ([3H]LHRH), and the profiles of metabolites generated as a function of time were determined.
(17) Based on these results, we suggest to call these substances (adenosine and pyro-glutamic acid) "selective modulators".
(18) The isolated light chain of factor XIa retained greater than 90% of its amidolytic activity against the oligopeptide substrate pyro-Glu-Pro-Arg-pNA (S-2366), but only 3.8% of its clotting activity in a factor XIa assay and 1% of its factor IX activating activity in an activation peptide release assay.
(19) Furthermore, electroplax membranes contain a whole set of enzymes responsible for the dephosphorylation of thiamine tri-, pyro- and monophosphate.
(20) The binding and uptake of the GnRH agonist D-Lys6-GnRH and of the antagonists [N-Ac-D-(pyro)-Cl-Phe1,2-D-Trp3-Lys6-D-Ala10]-GnRH and D-p-Glu1-D-Phe2-D-Trp3-D-Lys6-GnRH by dispersed pituitary gonadotropes was studied with electron microscopy.
Tyro
Definition:
(n.) A beginner in learning; one who is in the rudiments of any branch of study; a person imperfectly acquainted with a subject; a novice.
Example Sentences:
(1) Hence tyrO, tyrA, and aroF constitute an operon regulated by tyrR.
(2) When I first moved to Glasgow and was very much a tyro writer, I would occasionally wander off to Kelvingrove and potter.
(3) The radioligand [125I-Tyro]ovine CRF [( 125I] oCRF) was used to identify, characterize, and localize CRF receptors in a crude homogenate of mouse spleen.
(4) We have used PCR to identify 13 novel protein-tyrosine kinase genes (tyro-1 to -13), six of which (tyro-1 to -6) are preferentially expressed in the developing vertebrate nervous system.
(5) However, with 125I-Tyro-oCRF(34-41) as the radiolabeled ligand and Tyro-oCRF(34-41) as the standard, serial dilutions of CRF(1-41), CRF(36-41), and CRF(37-41) generated parallel displacement curves, and the molar cross-reactivities were 90%, 45% and 10% respectively.
(6) The rank order of potency of the unlabelled atrial natriuretic peptides for competing with specific 125I-ANF (101-126) binding sites was rANF (92-126) greater than rANF (101-126) greater than rANF (99-126) greater than rANF (103-126) greater than Tyro-Atriopeptin I greater than hANF (105-126) greater than rANF (1-126).
(7) In vitro receptor autoradiography, utilizing 125I-Tyro-ovine CRF, revealed correspondence between CRF binding sites and CRF-immunoreactive fibers in the cerebellar cortex.
(8) Rat, chick, and human CGRP and their synthetic analogues inhibited label binding in a dose-dependent manner with relative potencies as follows; chick greater than rat greater than human greater than [TyrO]rat CGRP.
(9) Yet the tyro managed to gather himself at two sets down, perhaps heeding the exhortations from his box to “Keep your head up Nick” (they might have omitted the up), and raced into a 3-0 lead in the third.
(10) 125I-Tyro rat CGRP binding sites were demonstrated throughout the rat central nervous system.
(11) But then Eriksen, the most understated of high-grade attacking midfielders, has always tended to operate by stealth, a gloriously talented 22-year-old who in his midweek post-training kit looks less like one of Europe's select band of tyro millionaire sportsmen and more like a trainee quantity surveyor just back from a lunchtime game of squash.
(12) Tyro-oCRF(34-41) was digested with trypsin and the reaction products were identified by amino acid analysis.
(13) The binding of 125I-[TyrO]rat CGRP to rat liver plasma membrane was time dependent, saturable and reversible.
(14) Rat CGRP and rat [Tyro]CGRP caused half-maximal effect at 2 nM, and were threefold more potent than human CGRP.
(15) In a pilot study, six postabsorptive young men received either 12- or 4-h infusions of [2H2]Phe and [1-13C]Tyr or [1-13C]Phe and [2H2]Tyro.
(16) The tyro-1 to -6 genes are all expressed during central nervous system neurogenesis and exhibit distinct and highly regionalized patterns of expression in the adult brain.
(17) Arya finally pitched up in Tywin Lannister's fastness, where she has become not just a poppet of a renegade tyro swordswoman but her dad's enemy's trainee cupbearer.
(18) The azide radical N3 reacts selectively with amino acids, in neutral solution preferentially with tryptophan (k (N3 + TrpH) = 4.1 X 10(9) dm3 mol(-1s-1) and in alkaline solution also with cysteine and tyrosine (k(N3 + CyS-) = 2.7 X 10(9) dm3 mol-1s-1) and k(N3 + TyrO-) equals 03.6 X 10(9) dm3 mol-1s-1).
(19) The nonhydrolyzable guanosine analogue guanosine 5'-(beta,gamma-imido)triphosphate was equipotent in causing a decrease in binding of 125I-[D-Tyro]NMB due to decreased receptor affinity in both cell types, without a change in receptor number, demonstrating that the NMB receptor remained coupled to a guanine nucleotide-binding protein in both native and transfected cells.
(20) In the present work, we have characterized by film radioautography the effects of divalent cations and guanine nucleotide on specific receptor for somatostatin (SRIF) using 125I-TyrO-DTrp8-SRIF14 (125I-ToD8-SRIF) as a ligand.