What's the difference between quadrupled and quadruplex?
Quadrupled
Definition:
(imp. & p. p.) of Quadruple
Example Sentences:
(1) Three effector: target ratios (6.2:1, 25:1, and 50:1) were studied in quadruplicate using 3, 4 and 5-h incubations.
(2) The largest increases in brain weights in both sexes occurred during the first 3 years of life, when the value quadruples over that at birth, while during the subsequent 15 years the brain weight barely quintuples over that at birth.
(3) They then decreased very slowly, according to a half-life of 122 h. Although it decreases glomerular filtration, ligation of ureters 20 h before the injection quadrupled the concentration in the cortex.
(4) Official estimates suggest the number of small packages shipped into Europe more than quadrupled from 26m in 2000 to 115m two years ago.
(5) The kinetics of intravenously administered FK506 was not changed from control status two weeks after bile duct ligation, but the bioavailability of orally administered FK506 was nearly quadrupled.
(6) There is a clear benefit of quadruple drug induction treatment for retransplants and sensitized transplant candidates.
(7) This patient achieved a complete remission with cyclic quadruple chemotherapy consisting of cyclophosphamide, vincristine, procarbazine, and prednisone (COPP).
(8) Null yuh1 ubp1 ubp2 ubp3 quadruple mutants are viable and retain the ability to deubiquitinate ubiquitin fusions, indicating the presence of at least one more ubiquitin-specific processing protease in S. cerevisiae.
(9) Guinea pig alveolar macrophages were infected in quadruplicate with log10 3.8 CFU of F889 cells grown at either 25 or 41 degrees C. Counts of F889 in the alveolar macrophages infected with 25 degrees C-grown bacteria were 40% greater after 1 day of incubation (P = 2 X 10(-4)) than were counts in the alveolar macrophage suspensions inoculated with 41 degrees C-grown bacteria.
(10) Shares acquired through privatisations rose steadily on the stock markets, while the buyers of council houses found that their assets tripled or quadrupled in value in the space of five years.
(11) An inductively coupled, quadruple-tuned surface coil with a 50-ohm match at all relevant frequencies was used for both excitation and receiving.
(12) Although both stores carried the same brands and varieties of produce, all 19 cases occurred among employees of one store, which had held a celery sale coincident with the outbreak, resulting in a quadrupling of the usual volume of celery sold.
(13) during the period of one year, that triple and quadruple resistance is the most prevalent one in staphylococci - not regarded, however, the penicillin resistance which is absolutely predominant.
(14) Sequence differences in the internally quadruplicated molecules, analysed in terms of their beta-sheets, hairpins and arches, give rise to structural differences in the motifs.
(15) Furthermore, a high percentage of multiple (quadruple or more) pancreatica magna and caudae pancreatis arteries has been observed and a functional role of this peculiar arrangement is suggested.
(16) BEATING THE CHEATING Owen Gibson’s five-point plan for reform 1 Hugely increase global funding Triple it, quadruple it.
(17) Surgery consisted in quadruple coronary bypass in 1 case, triple coronary bypass in 3 cases and double coronary bypass in 6 cases using 4 autologous saphenous vein grafts, 6 autologous internal mammary artery grafts and 13 bovine internal mammary artery grafts.
(18) The price of the specially formulated milk he requires has quadrupled since last year, so his parents have had to rent out their own home and move into a much smaller, rundown one just to feed their child.
(19) The High Pay Commission revealed earlier this week that while average pay has quadrupled since 1980s, top executives have seen their remuneration rise by 4,000%.
(20) Fourteen patients (56%) had double, triple or quadruple cancers.
Quadruplex
Definition:
(a.) Fourfold; folded or doubled twice.
Example Sentences:
(1) However, at a 50-fold higher strand concentration, the single-stranded oligomer is gradually converted into the quadruplex.
(2) We propose a model in which duplex or hairpin forms of G-DNA are folding intermediates in the formation of either 1-, 2-, or 4-stranded quadruplex structures.
(3) There has been much recent interest in the self-association of short deoxyguanosine-rich motifs within single-stranded DNAs to generate monovalent cation modulated four-stranded helical segments called G-quadruplexes stabilized by hydrogen-bonded G-tetrad alignments.
(4) Thus the number of T residues surrounding the dG cluster might control the rigidity of the quadruplex structure.
(5) Equilibrium ultracentrifugation studies confirm that these quadruplexes are composed of two strands of d(G3T4G3).
(6) The only precedent known (to us) for a cation-specific stabilization is that seen in the quadruplex structure formed by poly I.
(7) The quadruplex, [d(TTGGGGTT)]4, is resistant to denaturation in 7 M urea, in which the Watson-Crick type d(TTGGGGTT).d(AACCCCAA) duplex dissociates.
(8) We observe well-resolved proton NMR spectra corresponding to a G-quadruplex monomer conformation predominant at 50 mM K cation concentration and a G-quadruplex dimer conformation predominant at 300 mM K cation concentration.
(9) Our results indicate that specific differences in ionic interactions can result in a switch in telomeric DNAs between intramolecular hairpin-like or quadruplex-containing species and intermolecular quadruplex structures, all of which involve G.G base pairing interactions.
(10) The possible biological function of quadruplexes is discussed.
(11) The DNA oligonucleotide d(CGCG3GCG) can form either a Watson-Crick (WC) hairpin or a parallel-stranded quadruplex structure containing six G-quartet base pair assemblies.
(12) We find that these molecules fold to form a symmetrical bimolecular and an intramolecular quadruplex, respectively.
(13) An increase in ionic strength stabilizes the single-stranded structure, so it seems to inhibit the formation of the quadruplex.
(14) Experiments on ethidium bromide binding to the oligonucleotides have shown that the oligomer anti(A-T) exists, at a low ionic strength, as a four stranded complex ("quadruplex") contains two antiparallel helices, d(A).d(T), which have a parallel orientation and are bound to one another owing to the formation of additional hydrogen bonds between nucleic acid bases.
(15) The quadruplex is stable in the presence of 40 mM K+ at micromolar DNA concentration and can be kinetically trapped as a metastable form when prepared at millimolar DNA concentration and then diluted into buffer containing 40 mM Na+.
(16) Cations stabilize the quadruplex in the order K+ greater than Ca2+ greater than Na+ greater than Mg2+ greater than Li+ and K+ greater than Rb+ greater than Cs+, indicating that K+ has an optimum ionic radius for complex formation and that ionic charge affects the extent of ion-induced stabilization.
(17) Comparison with the corresponding CD spectral characteristics suggests that the electrophoretic intensity enhancement of the intermolecular G-quadruplex band is correlated to the intensity enhancement of of the positive CD maximum at 265 nm.
(18) Similar but less dramatic enhancement of the intermolecular quadruplex band is also observed in T4.
(19) Since K+ and NH4+ are known to stabilize a parallel-stranded quadruplex structure of poly[r(I)4], we infer that the multistranded structure is a quadruplex.
(20) UV thermal denaturation curves show a single concentration-dependent transition and provide data for quantitating the thermodynamics of quadruplex formation.