(a.) Consisting of four; by fours, or in sets of four.
(a.) Later than, or subsequent to, the Tertiary; Post-tertiary; as, the Quaternary age, or Age of man.
(n.) The number four.
(n.) The Quaternary age, era, or formation. See the Chart of Geology.
Example Sentences:
(1) The quaternary structure of ribonucleotide reductase of Escherichia coli was investigated, with the use of purified B1 and B2 proteins and bifunctional cross-linking agents.
(2) The sensitivity of an indirect fluorescent antibody (IFA) test (screening test) for the detection of antibodies to cytomegalovirus (CMV) was examined by using 128 serum specimens and quaternary aminoethyl (QAE)-Sephadex A50 column chromatography to separate IgM from IgG class antibodies.
(3) Modifications in quaternary structure induced by variation of these physicochemical parameters were followed by means of X-ray and quasi-elastic light-scattering and quantified in terms of weight average molecular weight (M), radius of gyration (Rg) and hydrodynamic radius (Rh).
(4) These features of the new quaternary structure, denoted Y, may therefore be representative of quaternary states that occur transiently along pathways between the normal unliganded, T, and liganded, R, hemoglobin structures.
(5) On the other hand, the lack of any twitch-potentiating effect by naloxone methylbromide, a quaternary derivative of naloxone, suggests that opioids which potentiate the twitch must enter the lipid phase of the membrane to act.
(6) Two additional quaternary ammonium compounds, tetraethylammonium and N1-methylnicotinamide, were not significantly bound to either tissue.
(7) These effects are due to residual silanols on the surface of the column material and may be remedied by adding suitable amines or quaternary ammonium ions to the eluent as anti-tailing agents.
(8) A quantitative thin layer chromatographic (TLC) method has been developed for determination of the antiarrhythmic quaternary ammonium compound N,N-bis (phenylcarbamoyl methyl) dimethylammonium chloride (QX-572) in biological materials.
(9) While currently available antiarrhythmic agents fail to achieve the desired effect, the recent evidence dealing with the quaternary ammonium derivatives of propranolol, lidocaine, and bretylium provides some hope for the future development of drugs with antiarrhythmic as well as antifibrillatory properties which may provide a therapeutic approach to the prevention of SCD.
(10) In case of non hydrolyzing salts, the quaternary ammonium bromide salts it could not surely be proved by the applied methods whether primary ion exchange had been followed by secondary ion exchange or only primary ion exchange had occurred.
(11) Naloxone methobromide (naloxone MB), a quaternary compound, was also effective in antagonising this effect of nalbuphine but was less effective than naloxone hydrochloride.
(12) Temperature, protein tertiary and quaternary structure, chain heterogeneity, and ligand rebinding subsequent to CO photolysis all affect the line width and position of this transition.
(13) Iodine-containing solutions and quaternary ammonium compounds rarely sensitize.
(14) Administration of the quaternary derivative, neostigmine, indicated that the effects of scopolamine at 22 days were probably central in origin.
(15) The relationships between thermodynamic quantities in a quaternary system of electrolytes are discussed in Appendix 2.
(16) Liquid crystals possess high density packing of DNA molecules complexed with quaternary ammonium salt of oligomer-25 conidin.
(17) Its quaternary dimethyl derivative, designated as pranolium was firstly prepared by Lucchesi.
(18) On the basis of these structural studies, we discuss the relationships between the conformational differences in the allosteric site and the small changes in the quaternary structure within the T form to the possible mechanisms for CTP inhibition and ATP activation.
(19) N,N-dimethylanatoxin (DMAnTX), the quaternary derivative of the potent nicotinic agonist (+)-anatoxin-a (AnTX), has been evaluated for potency and efficacy at nicotinic acetylcholine receptors of frog motor endplates and Torpedo electric organs.
(20) Reaction of the thiol reagent 5,5'-dithio-bis(2-nitrobenzoic acid) (Nbs2) with the brain-specific protein S-100 favours stabilization of the quaternary structure of the protein via disulfide bond formation.
Singular
Definition:
(a.) Existing by itself; single; individual.
(a.) Separate or apart from others; single; distinct.
(a.) Engaged in by only one on a side; single.
(a.) Each; individual; as, to convey several parcels of land, all and singular.
(a.) Denoting one person or thing; as, the singular number; -- opposed to dual and plural.
(a.) Standing by itself; out of the ordinary course; unusual; uncommon; strange; as, a singular phenomenon.
(a.) Distinguished as existing in a very high degree; rarely equaled; eminent; extraordinary; exceptional; as, a man of singular gravity or attainments.
(a.) Departing from general usage or expectations; odd; whimsical; -- often implying disapproval or consure.
(a.) Being alone; belonging to, or being, that of which there is but one; unique.
(n.) An individual instance; a particular.
(n.) The singular number, or the number denoting one person or thing; a word in the singular number.
Example Sentences:
(1) The combination of Azathioprine and Cyclosporin A brought with a 1-year function rate of 54% better results in comparison to the singular application of Azathioprine (22%) and Cyclosporin A (41%).
(2) But singular concern with the consequences of monopolistic control by the profession is no substitute for analysis of the dynamics among demand, production, and supply of surgery.
(3) The National Society to Prevent Blindness, formed in 1908, is the oldest voluntary agency with the singular mission to preserve sight and prevent blindness through a broad program of public and professional education, industrial and community services, and research.
(4) Nevertheless, studies on the occurrence of delayed neuronal death in the human brain have been singular and dealt with only small files of patients.
(5) Unfortunately, Hillary Clinton was advised once again by Beltway advisers who knew it all, had the models and the projections, but who called it wrong.” The USHCC was singularly invested in the outcome of Tuesday’s election, as it had endorsed Clinton for the presidency – the first time it has done so for any candidate in its 38-year history.
(6) Although singular neurectomy can be mastered, it will remain a procedure done by few surgeons.
(7) Thus, both tonB and fiu cir mutants showed a comparably reduced susceptibility to the probe compounds, whereas mutants singularly lacking any one of the six iron-regulated outer membrane proteins (Fiu, FepA, FecA, FhuA, FhuE, and Cir) or lacking any combination of any two of these proteins (except Fiu plus Cir) did not show this resistance.
(8) Each situation of terminal cases is absolutely singular and unique.
(9) A singular perturbation analysis of the 8-dimensional phase portrait of the model characterizes the role of calcium during the plateau phase of the ventricular action potential and demonstrates how the calcium refractory period prevents tetanization.
(10) Type 0 (strong) resetting occurred when respiratory drive was low, type 1 (weak) resetting when drive was high, and a phase singularity when drive was intermediate.
(11) We conclude that these equations could be used singularly or collectively to determine FFB, and a minimal weight could then be derived and assigned to a scholastic wrestler.
(12) Jim Gianopulos, the chairman of Fox Filmed Entertainment, went on a Singularity University course, and has since become evangelical about it.
(13) In contrast to neurons appearing in the pancreas of the sand rat, the neurons in the thyroid gland occur in most cases as singular neurons.
(14) In this paper we first review a modified form of the singularity decomposition of the FPP function accomplished within a prescribed error range.
(15) We could show that pathologic stress szintigrams were only found in patients with a singular stenosis in one branch of the left coronary artery.
(16) The advantages are: diminished risk of infections, local anesthesia instead of general anesthesia, applicability by the cardiologist in the catheterization-laboratory or under a simple fluoroscopy-unit, short stay of patients in the hospital without transfers to other departments, few personnel (1 scrubbed doctor, 1 non-scrubbed nurse), recognition of venous anomalies (singular left superior caval vein) without useless incisions for the patient.
(17) The resulting type, not to be identified by classical CFA, was shown to be singular and clear-cut with weakness in all 3 verbal tests.
(18) Udall barely mentioned government surveillance on the campaign trail, choosing instead to mount a singular focus on female voters, rarely straying from two topics : contraception and abortion.
(19) The presence of these microbacteria may provide a clue as to the late appearance, particular location, and singular clinical picture of pericoronitis.
(20) The results revealed that the conventional speaking tube was inferior to the electric hearing aid in terms of specificity to various frequencies, advantages and understanding of singular syllables, but almost equal to the latter in terms of understandings of three syllables.