(n.) A European scallop (Pecten opercularis), used as food.
Example Sentences:
(1) Further evaluation of the range of activity of several of these compounds, both in terms of the dose inducing a half-maximal response and the LHRH-releasing effect at that particular dose, indicated that AMPA greater than HCA greater than QUIN greater than PYR, suggesting that non-NMDA receptors are primarily involved in EAA-induced LHRH release at the level of the AN-ME.
(2) Unilateral infusions of quinolinic acid (QUIN) into the rat striatum led to an increase in cholecystokinin octapeptide sulfate-like immunoreactivity (CCK8S-LI) in the striatum and substantia nigra 4 days later.
(3) Intraplatelet free calcium (Ca2i+) was measured in 25 patients, using the fluorescent indicator Quin-2.
(4) By examining in parallel the digitonin-induced release of exogenous fluorescent or luminescent indicators, a granule location was demonstrated for the pH indicator 9-aminoacridine, while the calcium probes aequorin and Quin 2 were released coincident with release of the cytosolic enzyme lactate dehydrogenase.
(5) Fluorescent indicator Quin-2 was used for the determination of free calcium (Ca2+in) in synaptosomes incubated in the normal medium and media where sodium is replaced by potassium or choline.
(6) The same neuronal populations were also selectively killed by N-methyl-D-aspartate (NMDA) but the toxic potency of NMDA was 40-fold higher than that of QUIN.
(7) Phorbol 12-myristate, 13-acetate, the calcium ionophore A23187 in the presence or absence of EGTA, and the fluorescent calcium chelator quin-2 also cause an increase in cytoskeletal actin.
(8) Amylase secretion, but not the Quin 2 fluorescence response, was attenuated at higher secretagogue concentrations.
(9) Ca2+ transport by DECYL-2E (I, R = n-decyl) - monitored by measurements of the fluorescence of an intracellular dye, quin-2 - occurred at a rate comparable to that produced by electroneutral Ca2+ ionophores ionomycin and Br-A23187.
(10) [13C6]QUIN was detected in the incubation medium of both unstimulated and stimulated cultures.
(11) Adrenaline and collagen had no effect in promoting intracellular Ca2+ increase as measured with Quin-2 and little effect when measured with Fura-2.
(12) Under these conditions, phospholipase A2 activity, as detected by the release of [14C]arachidonate and of its metabolites, or by the hydrolysis of [14C]phosphatidylcholine, was severely impaired in quin 2-loaded platelets upon removal of external Ca2+.
(13) We have used intracellular Quin 2, and extracellular Ca2+ without the use of EGTA or ionophores to manipulate the levels of intracellular Ca2+.
(14) Since the cytosolic calcium concentration may mediate the effects of extracellular calcium on PTH release, we have employed the calcium-sensitive intracellular dye QUIN-2 to examine the relationship between extracellular calcium, cytosolic calcium, and PTH secretion in adult, neonatal, and cultured bovine as well as pathological human parathyroid cells.
(15) We conclude that sustained moderate increases in CSF QUIN occur in viremic simian retrovirus type-D macaques.
(16) Br-A23187 is shown to saturate Ca2+ sites in quin-2-loaded rat thymic lymphocytes in a manner essentially identical to ionomycin.
(17) Gill Quine, senior solicitor, says: "Our campaigning as a team has helped to keep morale up, but in the next few days we lose three valuable staff members whose qualifications, experience and commitment will be a great loss to the residents of Rochdale.
(18) It was observed that the D-2 receptor agonist quinpirole (QUIN) produced biphasic effects on cell firing rate.
(19) Using simultaneous analyses of cell function and Quin 2 fluorescence, we find that at least two aspects of cellular responsiveness (degranulation and O2- production) depend upon the level of available Ca2+.
(20) A comparison between the fluorescent indicator quin 2 and the bioluminescent indicator aequorin was performed in the same smooth muscle cell type.
Ruin
Definition:
(n.) The act of falling or tumbling down; fall.
(n.) Such a change of anything as destroys it, or entirely defeats its object, or unfits it for use; destruction; overthrow; as, the ruin of a ship or an army; the ruin of a constitution or a government; the ruin of health or hopes.
(n.) That which is fallen down and become worthless from injury or decay; as, his mind is a ruin; especially, in the plural, the remains of a destroyed, dilapidated, or desolate house, fortress, city, or the like.
(n.) The state of being dcayed, or of having become ruined or worthless; as, to be in ruins; to go to ruin.
(n.) That which promotes injury, decay, or destruction.
(n.) To bring to ruin; to cause to fall to pieces and decay; to make to perish; to bring to destruction; to bring to poverty or bankruptcy; to impair seriously; to damage essentially; to overthrow.
(v. i.) To fall to ruins; to go to ruin; to become decayed or dilapidated; to perish.
Example Sentences:
(1) Because they generally have to be positioned on hills to get the maximum benefits of the wind, some complain that they ruin the landscape.
(2) Even regional allies disagree with American priorities about Isis, Biddle noted, which is why Turkey continues to bomb Kurds and Saudi Arabia and the UAE arm groups around the region , most notably in Syria but also in the ruins of Yemen .
(3) It trickled back to me somehow that, ‘Goddammit, Johnny Depp’s ruining the film!
(4) A procedure is described for the rapid determination of putrascine, spermine and spermidine in ruine and whole blood.
(5) Hitchcock's attempts to keep Hedren in a gilded cage arguably ruined her career.
(6) Conference, five years ago this motion would have ruined my life.
(7) But illegal action will only ruin any chance of dialogue with Tehran.
(8) The lid is fiddly to fit on to the cup, and smells so strongly of silicone it almost entirely ruins the taste of the coffee if you don’t remove it.
(9) In Niki Savva’s book The Road to Ruin: How Tony Abbott and Peta Credlin Destroyed Their Own Government, Credlin has even been compared to Wallis Simpson, a deeply weird analogy.
(10) "While the country is sunk in misery, families are ruined and children are growing up in poverty, this guy turns up and we pay €91m for him.
(11) Anuraj Sivarajah, online editor of the newspaper, said he was very clear who was to blame for the attacks and arson that has brought the newspaper near financial ruin.
(12) In 1995 8,000 people whose lives were ruined by the Montserrat volcano settled in Britain.
(13) They belong to the people who built Choquequirao, one of the most remote Inca settlements in the Andes, and were stashed here by the archaeologists who, over the past 20 years, have been slowly freeing the ruins from the cloud forest.
(14) Even the avuncular governor of the Irish central bank, Professor Patrick Honohan, was forced to admit that pumping up to €70bn of taxpayers' money into the ruined banks "doesn't score highly on fairness" when he announced the fifth bailout on Thursday.
(15) Three thousand cheers for Will Self ( Has English Heritage ruined Stonehenge?
(16) But Denton’s attempts to apply extreme openness to others could cost the ruin of his company.
(17) His torturers accused him of passing on to British officials information about previous beatings at the hands of state officials and other human rights abuses, to ruin diplomatic relations between the two countries, he said.
(18) As Google states, it is definitely in the company’s best interest to get its first smartglass customers to behave, as “breaking the rules or being rude will not get businesses excited about Glass and will ruin it for other Explorers”.
(19) The notion that Gleeson has lurched from one disaster to another, ruining everything from the Coen brothers' remake of True Grit to Richard Curtis's romcom About Time , seems a pretty unique interpretation of his burgeoning career as a versatile character actor.
(20) But there was scepticism over whether the more radical elements on either side would obey the ceasefire, and concern in Kiev and western capitals that the truce would effectively "freeze" the conflict and give Moscow de facto control over the disputed chunk of eastern Ukraine that has been ruined by war this summer.