(n.) A colorless liquid of a slightly pungent odor, C9H6N.CH3, first obtained as a condensation product of aldehyde and aniline, and regarded as a derivative of quinoline; -- called also methyl quinoline.
Example Sentences:
(1) In addition, some quinaldine red may be present in the cytoplasm in an aggregated, ionically bound form.
(2) The following degradation products of quinaldine were isolated from the culture fluid and identified: 1H-4-oxoquinaldine, N-acetylisatic acid, N-acetylanthranilic acid, anthranilic acid, 3-hydroxy-N-acetylanthranilic acid and catechol.
(3) However, uptake as well as subsequent ionic binding of quinaldine red seems to be related to potential in an as yet undefined manner.
(4) A major aspect of the change is that in sodium-loaded cells, essentially all of the quinaldine red accumulated as the result of energization forms a strong bond with an anionic group.
(5) 4-(2'-, 4'-nitro- and 2',4'-dinitrobenzenesulfenamido)-quinaldines (I--III) as well as 2-(2'-,3'-nitro and 2',4'-dinitrobenzensulfenamido)-46-oimethylpyrimidines (IV--VI) were obtained.
(6) 2-Hydroxymethylquinoline and quinaldine are found in nonfresh greyhound urine as putrefactive bases.
(7) 2-aminomethylquinoline is excreted in fresh urine and two others, quinaldine and 2-hydroxymethylquinoline, are formed as the urine decays.
(8) The determination of dichloralantipyrine is based on the fact that it, as well as its major metabolite chloral hydrate, produces a blue color with quinaldine ethiodide.
(9) Solvent Yellow 33 (German: Rauchgelb) belongs to the groups of quinaldine dyes which are produced by condensing quinaldine and phthalic anhydride.
(10) The general characteristics of the cation employed, quinaldine red, closely paralleled those of other amphiphilic cations which have been used to measure membrane potential.
(11) The aggregates were estimated to contain at least five quinaldine red cations at or near van der Waals contact, and the presence of other molecules, such as phospholipids, could not be excluded.
(12) Quinaldine catabolism was investigated with the bacterial strain Arthrobacter sp., which is able to grow aerobically in a mineral salt medium with quinaldine as sole source of carbon, nitrogen and energy.
(13) Type A monoamine oxidase (MAO-A) in human placental mitochondria was competitively inhibited by naturally occurring substances, quinoline and quinaldine, using kynuramine as substrate.
(14) This binding is similar to that which occurs for the basal level of quinaldine red taken up in nonenergized cells.
(15) Uptake of the anesthetics tricaine methanesulfonate, benzocaine, Piscaine, and quinaldine is rapid because they are lipophilic.
(16) Production of 2-hydroxymethylquinoline or quinaldine is not arrested but merely retarded by preservation or refrigeration.
(17) The results show that membrane potential cannot be computed in a simple manner from the distribution of quinaldine red between cells and medium, assuming that the thermodynamic activity coefficient of cell-localized material is identical with that in dilute aqueous solution.
(18) The dithioacetic acid zwitterions were prepared from the base-catalyzed reaction of carbon disulfide with quinaldine and picoline methiodides, and the bis(methylthio) derivatives resulted from reaction with methyl iodide at room temperature.
(19) A method for the measurement of quinaldine and 2-hydroxymethylquinoline using gas chromatography is described.
(20) 2-Hydroxymethylquinoline forms in greyhound urine, if non-preserved, in three or four days at room temperature while quinaldine takes as much as 10 days longer to form.
Sedative
Definition:
(a.) Tending to calm, moderate, or tranquilize
(a.) allaying irritability and irritation; assuaging pain.
(n.) A remedy which allays irritability and irritation, and irritative activity or pain.
Example Sentences:
(1) The effects of sessions, individual characteristics, group behavior, sedative medications, and pharmacological anticipation, on simple visual and auditory reaction time were evaluated with a randomized block design.
(2) Open field behaviors and isolation-induced aggression were reduced by anxiolytics, at doses which may be within the sedative-hypnotic range.
(3) However, the degree of sedation caused by diphenhydramine was significantly greater than that caused by cimetidine (P = .0001).
(4) Although lorazepam and haloperidol produced an equivalent mean decrease in aggression, significantly more subjects who received lorazepam had a greater decrease in aggression ratings than haloperidol recipients; this effect was independent of sedation.
(5) Adverse outcomes were reported more frequently by consultant physicians, by those who 'titrated' the intravenous sedative, and by those who used an additional intravenous agent, but were reported equally frequently by endoscopists using midazolam and endoscopists using diazepam.
(6) Alterations in mean systolic blood pressure appeared to be modest, consisting of a 10 percent decrease from the control level, related to sedation, and a 10 percent rise from baseline during the procedure, associated with a concomitant mild tachycardia.
(7) We have evaluated the action of hypnotics on the sleep-wakefulness cycle in freely implanted rats during their maximally active period because it is easier to estimate the duration of the sedative effect.
(8) A survey into the current usage of tracheal tubes and associated procedures, such as various sedation regimes and antacid therapy, in intensive care units was carried out in Sweden by sending a questionnaire to physicians in charge of intensive care units in 70 acute hospitals which included seven main teaching hospitals.
(9) The results show that both drugs possess sedative, antispasmodic, antipyretic, antiinflammatory, cardiotonic and hypotensive effects, the strength of effect and toxicity being similar.
(10) This suggests that the fluphenazine-induced sedation is not mediated via its effect on brain NA content, but is possibly due to the effect of the drug on NA turnover rates in the brain.
(11) The introduction of non-sedating H1-selective antihistamine drugs and local corticosteroids has been an important therapeutic advance.
(12) Neither a sedative nor other side effects could be seen.
(13) Sedation was measured by asking the subjects to complete visual analog scales.
(14) Smoking behaviour, self-reported mood and cardiac activity were examined in 12 "sedative" and 12 "stimulant" smokers, defined using Mangan and Golding's questionnaire.
(15) Patients in the reference group used more sedatives and long-acting nitroglycerine and had a lower return-to-work rate during the study period.
(16) A prospective study of the necessity of sedation, or analgesia, or both in total colonoscopy was performed.
(17) Fifteen consecutive patients on peritoneal dialysis who complained of chronic sleep disturbance and requested sedative were selected.
(18) Sedative interaction between midazolam and morphine was found to have a tendency for synergism (interaction coefficient of 1.56, P greater than 0.05) with decreased individual variability in the sedative response to the combination.
(19) Both drugs were relatively well tolerated, but trimipramine had a sedative effect which proved troublesome in some patients.
(20) None of the patients required anaesthesia, analgesics or sedatives.