(a.) Pertaining to, derived from, or connected with, quinine and related compounds; specifically, designating a nonnitrogenous acid obtained from cinchona bark, coffee, beans, etc., as a white crystalline substance.
Example Sentences:
(1) In Neurospora crassa, the qa-1F regulatory gene positively controls transcription of all genes in the quinic acid (qa) gene cluster.
(2) The qa genes are induced by quinic acid and are coordinately controlled at the transcriptional level by the positive and negative regulators, qa-1F and qa-1S, respectively.
(3) The data indicate a chelation of the alpha-hydroxycarboxylic acid part of quinic acid to platinum(II).
(4) A number of constitutive (qa-1(C)) mutants have been obtained from certain qa-1 mutants as revertants selected for their ability to grow on quinic acid as a sole source of carbon.
(5) A large number of quinic acid non-utilizing qut mutants of Aspergillus nidulans deficient in the induction of all three quinic acid specific enzymes have been analysed.
(6) Mean percent recoveries of each acid were quinic 95.4 (std dev.
(7) Catabolic dehydroquinase which functions in the inducible quinic acid catabolic pathway in Neurospora crassa has been purified 8000-fold.
(8) After steaming of 4 green coffee's the content of quinic acid was always higher, but no quinide had been formed.
(9) In Neurospora crassa, the enzyme quinate (shikimate) dehydrogenase catalyzes the first reaction in the inducible quinic acid catabolic pathway and is encoded in the qa-3 gene of the qa cluster.
(10) The shikimate pathway and the quinic acid utilisation (QUT) pathway of Aspergillus nidulans and other fungi share the two common metabolic intermediates, 3-dehydroquinic acid (DHQ) and dehydroshikimic acid (DHS), which are interconverted by two isoenzymes, catabolic 3-dehydroquinase, (cDHQase) and biosynthetic dehydroquinase, (bDHQase).
(11) In addition we showed that a qutE mutant (lacking cDHQase) can grow with quinic acid as sole carbon source whtn the arom protein is overproduced fivefold.
(12) Succinic, fumaric, and quinic acids are wide spread, tartaric acid was found in carrots, lettuce, endives, chicory, and celery.
(13) A concentration of quinic acid or shikimic acid as low as 50 micron protects the enzyme markedly from heat inactivation.
(14) Enzyme assays indicated that the specific activities of catabolic dehydroquinase induced by quinic acid in the transformants ranged from 4% to 32% of that induced in wild-type N. crassa.
(15) Quinic acid and its lactone (quinide) have been determined in coffee by capillary gas chromatography.
(16) Possible precursors of these o-diphenols (quinic acid, aromatic monohydroxy acids, or tyrosine) do not give rise to the brown pigmentation.
(17) The 5'-flanking regions of the five qa structural genes and the two qa regulatory genes each contain DNase I hypersensitive sites under noninducing conditions and generally exhibit increases in DNase I cleavage upon induction of transcription with quinic acid.
(18) Liquid chromatography was used for quantitation of sugars (glucose, fructose, sucrose, and sorbitol), nonvolatile acids (malic, quinic, citric, shikimic, and fumaric), and phenolics (chlorogenic acid and hydroxymethylfurfural [HMF]).
(19) Seventeen ambulant outpatients with familial Type IIa or Type IIb hyperlipoproteinaemia were treated with Cynarin, the 1,5-dicaffeyl ester of quinic acid, the constituent of the artichoke (Cynara scolymus).
(20) qa-1F is transcribed at a low, uninduced level but is subject to strong (50-fold), autogenous regulation as well as to control by the negative regulatory gene, qa-1S, and the inducer quinic acid.