(a.) Of or pertaining to rachitis; affected by rachitis; rickety.
Example Sentences:
(1) Rachitic bone lesions were only partially corrected by the high-Ca diet.
(2) Demineralized rachitic bone (RB) implanted into normal host rats resulted in cartilage and bone induction similar to that seen for normal bone (NB) implants.
(3) In vitro binding of 25-hydroxycholecalciferol (25-(OH)D3) and 1alpha,25-dihydroxycholecalciferol (1,25-(OH)2D3) was studied in the duodenal mucosa cytosol of rachitic rats: both 25-(OH)D3 and 1,25-(OH)2D3 bind to a macromolecule (sedimentation coefficient 5.5 to 6 S in low or high ionic strength) with a high affinity (KD at 4 degrees C = 1.2 X 10-9M and 2 x 10-9M, respectively).
(4) Measurements of 45Ca uptake by rachitic cartilage slices from metastable calcium phosphates solution also indicated inhibition of calcification by heat.
(5) Some of the factors predisposing to rickets were assessed in the rachitic children and in age-matched controls.
(6) The biological activity of 11 alpha-methyl-1 alpha,25-(OH)2D3 closely resembled that of the natural hormone on normal and leukemic cell proliferation and bone resorption, whereas its in vivo effect on calcium metabolism of the rachitic chick was about 50% of that of 1 alpha,25-(OH)2D3.
(7) In the rachitic animal, arterioles, venules, and capillaries were found adjacent to the growth plate, either directly apposed to the hypertrophic chondrocytes or separated from them by bone-forming cells.
(8) The coefficient of correlation between adult height (expressed as standard deviation score) and the average rachitic activity or score was -0.796 (p less than 0.01), indicating that adult height varied inversely with the severity of the disease.
(9) Severe demineralization (greater than -3 SD) was found in four rachitic patients with tubulointerstitial disease.
(10) Rachitic changes were detectable by light microscopy and microradiography in chicks whose skeletons appeared normal roentgenographically.
(11) Parvalbumin was found to be independent of the vitamin D status of the animal since its concentration remained unchanged in kidney extracts of normal, rachitic and vitamin D-replete rats.
(12) In the present studies, we tested the ability of rachitic versus normal rat growth plate chondrocytes in micromass or monolayer primary cultures to produce MVs.
(13) These intestinal complexes were less well developed, decreased in number, and quite often absent, in the apical cytoplasm of absorptive cells from rachitic chicks.
(14) The addition of calcium-binding protein to rachitic mucosa prior to homogenization does not yield a Triton X-100 solubilizable form, indicating that bound calcium-binding protein in vitamin D-replete intestine is not due to adsorption or vesicular entrapment of soluble calcium-binding protein.
(15) Although the rachitic cartilage does mineralize, discontinuities in the mineral distribution are much more severe, with the general failure of fusion of adjacent mineral clusters.
(16) Rachitic changes were induced in young rats by giving dietary Mn (2%) or by phosphate depletion (0.02% P) for 25 days.
(17) Radioisotope studies have shown that collagen synthesized in the shafts of bones from rachitic rats and chicks is similar in chain composition to that normally synthesized.
(18) Indeed these vascular channels appeared to be a basic architectural feature of normal cartilage, although disorganized in the rachitic state.
(19) This hereditary syndrome of renal hypophosphataemia differs from the common familial X-linked hypophosphataemia and the recently described autosomal recessive hypophosphataemic rickets with hypercalciuria by its dominant mode of inheritance; it differs from hypophosphataemic non-rachitic bone disease by the elevated serum 1,25 dihydroxyvitamin D levels and hypercalciuria.
(20) After ultracentrifugation of C(f1) of normal, rachitic, and healing rachitic animals, nonprotein-bound calcium (Ca(f)) and phosphate (P(if)) were determined on supernatant fluids.
Rachitis
Definition:
(n.) Literally, inflammation of the spine, but commonly applied to the rickets. See Rickets.
(n.) A disease which produces abortion in the fruit or seeds.
Example Sentences:
(1) The lipid composition and structure of low- and high-density lipoproteins (LDL and HDL) have been studied in children with the vitamin D-deficient rachitis.
(2) Indices of oxygen supply are studied in preadolescent rats with experimental rachitis.
(3) The submicroscopic organization and activity of acid phosphatase and catalase in lysosomes and peroxisomes of the rat hepatocytes were studied with experimental rachitis.
(4) In order to optimize the rachitis-prophylaxis in the GDR we comment on the problems and dangers by vitamin-D-overdosages on the basis of animal-experimental and clinical examinations.
(5) In this case manifestation of the tissue hypoxia in animals with experimental rachitis weakens and at the same time metabolic disturbances are eliminated.
(6) The question of the relation of these findings to the inactivity, osteomalacia and changes in metabolism in rachitis was discussed.
(7) Biochemical aspects of the development of the 3 different forms of genetically conditioned rachitis are shown.
(8) Content of glycogen and lactic acid was decreased in sceletal muscles of growing male rats during the acute periof of experimental rachitis.
(9) The morphometric examination showed muscle fibre diameters 8--24 mu less than those of healthy control rats in correlation with the degree of rachitis.
(10) Disturbances in transport, capillary-tissue diffusion and oxygen utilization by tissues of the brain, liver and skeletal muscles correlating with a degree of the rachitis gravity are revealed.
(11) It is determined that total and free activity of acid phosphatase in the liver tissue and certain lysosomes with rachitis increases whereas the catalase activity in the tissue and certain peroxisomes decreases.
(12) It is established that under experimental rachitis intensity of the radioactive label incorporation into soluble collagen is 1.7 times as low as in the norm.
(13) The data obtained suggest that excess of phosphorus is apparently important for pathogenesis of rachitis and the optimal ratio Ca : P should not be ignored in child diet.
(14) UV-irradiation of animals suffering from rachitis intensifies cholesterol synthesis in skin.
(15) The diagnosis of a hypophosphatemic vitamin-D-resistant rachitis in this child could only be established with certainty during the course of the following months.
(16) Radiologically and chemically, a rachitis was found which clearly improved following administration of 600,000 U. vitamin D3.
(17) osteogenesis imperfecta or rachitis), but especially when bone tumors or tumorlike changes are present.
(18) In order to avoid a potential danger of arteriosclerosis the rachitis-prophylaxis in infants and babies should be taken up with physiological vitamin-D-dosages.
(19) Potassium orotate and guanine are established to accelerate the duodenum physiological response of chickens with experimental rachitis to administration of vitamin D3 in the in vivo experiments.
(20) The condition can be distinguished from Mb Blount, prenatal genu varum, hypophosphataemia, rachitis, and post-traumatic genu varum in its course, roentgenological picture, and laboratory examination.