(n.) Literally, inflammation of the spine, but commonly applied to the rickets. See Rickets.
(n.) A disease which produces abortion in the fruit or seeds.
Example Sentences:
(1) The lipid composition and structure of low- and high-density lipoproteins (LDL and HDL) have been studied in children with the vitamin D-deficient rachitis.
(2) Indices of oxygen supply are studied in preadolescent rats with experimental rachitis.
(3) The submicroscopic organization and activity of acid phosphatase and catalase in lysosomes and peroxisomes of the rat hepatocytes were studied with experimental rachitis.
(4) In order to optimize the rachitis-prophylaxis in the GDR we comment on the problems and dangers by vitamin-D-overdosages on the basis of animal-experimental and clinical examinations.
(5) In this case manifestation of the tissue hypoxia in animals with experimental rachitis weakens and at the same time metabolic disturbances are eliminated.
(6) The question of the relation of these findings to the inactivity, osteomalacia and changes in metabolism in rachitis was discussed.
(7) Biochemical aspects of the development of the 3 different forms of genetically conditioned rachitis are shown.
(8) Content of glycogen and lactic acid was decreased in sceletal muscles of growing male rats during the acute periof of experimental rachitis.
(9) The morphometric examination showed muscle fibre diameters 8--24 mu less than those of healthy control rats in correlation with the degree of rachitis.
(10) Disturbances in transport, capillary-tissue diffusion and oxygen utilization by tissues of the brain, liver and skeletal muscles correlating with a degree of the rachitis gravity are revealed.
(11) It is determined that total and free activity of acid phosphatase in the liver tissue and certain lysosomes with rachitis increases whereas the catalase activity in the tissue and certain peroxisomes decreases.
(12) It is established that under experimental rachitis intensity of the radioactive label incorporation into soluble collagen is 1.7 times as low as in the norm.
(13) The data obtained suggest that excess of phosphorus is apparently important for pathogenesis of rachitis and the optimal ratio Ca : P should not be ignored in child diet.
(14) UV-irradiation of animals suffering from rachitis intensifies cholesterol synthesis in skin.
(15) The diagnosis of a hypophosphatemic vitamin-D-resistant rachitis in this child could only be established with certainty during the course of the following months.
(16) Radiologically and chemically, a rachitis was found which clearly improved following administration of 600,000 U. vitamin D3.
(17) osteogenesis imperfecta or rachitis), but especially when bone tumors or tumorlike changes are present.
(18) In order to avoid a potential danger of arteriosclerosis the rachitis-prophylaxis in infants and babies should be taken up with physiological vitamin-D-dosages.
(19) Potassium orotate and guanine are established to accelerate the duodenum physiological response of chickens with experimental rachitis to administration of vitamin D3 in the in vivo experiments.
(20) The condition can be distinguished from Mb Blount, prenatal genu varum, hypophosphataemia, rachitis, and post-traumatic genu varum in its course, roentgenological picture, and laboratory examination.
Rickets
Definition:
(n. pl.) A disease which affects children, and which is characterized by a bulky head, crooked spine and limbs, depressed ribs, enlarged and spongy articular epiphyses, tumid abdomen, and short stature, together with clear and often premature mental faculties. The essential cause of the disease appears to be the nondeposition of earthy salts in the osteoid tissues. Children afflicted with this malady stand and walk unsteadily. Called also rachitis.
Example Sentences:
(1) A survey carried out two and three years after the launch of the official campaign also showed a reduction in the prevalence of rickets in children taking low dose supplements equivalent to about 2.5 micrograms (100 IU) vitamin D daily.
(2) Phenobarbital did not retard growth nor impede the response to vitamin D therapy of concomitant rickets.
(3) Where UV radiation is restricted, individual propensity to rickets within a given Asian community is mainly determined by dietary factors.
(4) In a large commercial goat farm rickets-like symptoms were diagnosed in goat kids.
(5) One of the metabolites proved to be as active as the parent vitamin in curing rickets and was found in large amounts in liver, blood, and bone.
(6) The influence of extra phosphorus (P) and calcium (Ca) on the incidence of rickets was studied in 40 infants with a birthweight below 1.5 kg.
(7) The healing of rickets, the stimulation of intestinal Ca and P transport, the effect on bone mineral, and the induction of renal calcifications have been examined.
(8) It has been confirmed that the foetal parathyroid glands are important in development and that thyroparathyroidectomy (TXPTX) of the ovine foetus with thyroxine (T4) replacement leads to hypocalcaemia, retarded skeletal development, depressed calcification and rickets, relative to thyroidectomy plus T4 replacement.
(9) A boy with Lowe syndrome who manifested renal Fanconi syndrome by severe hypophosphatemic rickets, failure to thrive, and metabolic acidosis failed to improve with conventional bolus therapy of phosphate and bicarbonate.
(10) Some of the factors predisposing to rickets were assessed in the rachitic children and in age-matched controls.
(11) Vitamin D deficiency contributes to bone demineralization and rickets.
(12) Lymphocyte cell lines were established from five patients with vitamin D-dependent rickets, type II (VDDR-II).
(13) Clinical signs of rickets are still absent at this time, while an increased activity of the serum alkaline phosphatase signals the beginning of the illness.
(14) The majority of this thickening was due to an increase in the zone of proliferation, identical to that which occurs in calcium-deficiency rickets.
(15) A 22-month-old girl with cystinotic rickets was given 1 microgram 1,25-dihydroxycholecalciferol (1,25-DHCC) daily in addition to standard treatment.
(16) The patients were divided into 5 groups, 1) Osteomalacia and rickets 42 cases, showing typical changes of bone in X-ray films.
(17) In addition, the improved growth and healing of rickets further attest to the efficacy of the new treatment.
(18) In contrast, it appears that doses of either drug that are curative in D deficiency rickets are only partly active in PDR.
(19) During the latter half of an infant's first year, adequate mineral and vitamin D intakes may be important not only for the prevention of rickets but also for the attainment of optimal adult peak bone mass.
(20) Renal tubular dysfunctions with secondary rickets may be lacking altogether, even in chronic patients.