(n.) Rent or worn into tatters, or till the texture is broken; as, a ragged coat; a ragged sail.
(n.) Broken with rough edges; having jags; uneven; rough; jagged; as, ragged rocks.
(n.) Hence, harsh and disagreeable to the ear; dissonant.
(n.) Wearing tattered clothes; as, a ragged fellow.
(n.) Rough; shaggy; rugged.
Example Sentences:
(1) Over the past 20 years the rag-and-bone trade has had a makeover.
(2) I usually use them as a rag with which to clean the toilet but I didn’t have anything else to wear today because I’m so fat.” While this exchange will sound baffling to outsiders, to Brits it actually sounds like this: “You like my dress?
(3) Confluent monolayers of capillary endothelial cells derived from Mongolian gerbil brain were irradiated with a single exposure of x-rays, and their radiosensitivity and sequential changes in morphology, staining intensity for factor VIII-related antigen (F VIII RAg), and capacity to produce prostacyclin (PGI2) were examined.
(4) Skeletal muscle mtDNA of three patients with mitochondrial encephalomyopathy, characterized clinically by myoclonic epilepsy and ragged-red fiber (MERRF) syndrome, has been sequenced to determine the underlying molecular defect(s).
(5) A distinctive pattern of subsarcolemmal mitochondrial aggregates, referred to as "ragged red fibers" in human mitochondrial myopathies, was observed in muscle biopsy samples from 1 dog.
(6) Endothelial cells of capillary vessels showed positive binding by UEA-1 lectin and the presence of factor VIII RAG.
(7) Four of the mutants had no effect on chylous ascites, but two mutants linked with ragged, and one unlinked, showed a complex situation involving enhancement, inhibition, epistacy and other interactions.
(8) There was a slight shortening in the thrombin time and a smaller increase in post-operative FVIII RAg and FVIII RCof levels in the HES group.
(9) There was no correlation between FVIII:RAg levels and radiation pneumonitis, radiation dose, volume of irradiated lung, tumor burden, or time-interval between exposure and sampling.
(10) In one of these, a probe designed specifically to detect deleted mtDNA identified abundant deleted mtDNA and its fusion transcript in RRF and lesser accumulations in non-ragged red cytochrome oxidase (COX) deficient fibres.
(11) Only in fragments of the biceps brachii muscle histological and histochemical investigations showed mitochondrial changes of the type of "ragged-red fibres".
(12) In situ hybridization to intact thymus and RNA blot analysis of isolated thymic subpopulations separated on the basis of T cell receptor (TCR) expression demonstrated that both TCR- and TCR+ cortical thymocytes express RAG-1 and RAG-2 messenger RNA's.
(13) Nuclear run-on assays showed that TPA completely repressed the transcription of RAG-1 within 30 min.
(14) A former Socialist party leader, he is a jovial, wise-cracking believer in consensus politics, who aides say never loses his rag and who so hates fights that he was once nicknamed "the marshmallow" within his own party, or "Flanby", after a wobbly caramel pudding.
(15) The Farage adviser said he looked back on many people within Ukip as “a bunch of rag-tag, unprofessional, embarrassing people who let Nigel down at every juncture.” He told the Guardian: “Someone needs to go in there with a big stick.
(16) Furthermore, we show that RAG can be expressed not only by CD3-TCR negative but also by CD3-TCRab or gd positive T-ALL cells.
(17) After fusion of HPRT- RAG cells with E. lutescens fibroblasts we demonstrated that the enzymes HPRT and G6PD are localized on the presumptive X chromosome.
(18) We analyzed the mitochondrial DNA of blood cells of 5 patients from a Chinese family with myoclonic epilepsy and ragged-red fiber disease.
(19) A small percentage of peripheral B cells also contained RAG-1 mRNA, raising the possibility that this protein may also be involved in immunoglobulin class switching.
(20) Exposure of isolated thymocytes to 12-O-tetra-decanoylphorbol 13-acetate (TPA)+ionomycin rapidly abolishes the expression of recombination-activating gene-1 (RAG-1) mRNA (3 h), down-regulates CD4 surface antigen expression (3 h), and enhances apoptosis (24 h).
Toad
Definition:
(n.) Any one of numerous species of batrachians belonging to the genus Bufo and allied genera, especially those of the family Bufonidae. Toads are generally terrestrial in their habits except during the breeding season, when they seek the water. Most of the species burrow beneath the earth in the daytime and come forth to feed on insects at night. Most toads have a rough, warty skin in which are glands that secrete an acrid fluid.
Example Sentences:
(1) A golden toad (Bufo periglenes) in Monteverde Cloud forest reserve in Puntarenas province of Costa Rica.
(2) Resting plasma epinephrine and norepinephrine levels were 13.1 and 2.1 nmol liter-1 for the marine toad (Bufo marinus).
(3) A study was made of the innervation of the longitudinal muscle of the toad ileum with particular emphasis on the splanchnic innervation by non-adrenergic, non-cholinergic (NANC) nerves.
(4) These results indicate that GE decreases active Na transport in the toad skin.
(5) Fenoterol significantly increased toad skin oxygen consumption and net Na+ movement across the skin due to an increase in Na+ flux from mucosa to serosa.
(6) We attempted to distinguish between these 2 possibilities by studying paired toad bladders during 3 protocols that alter vasopressin-stimulated water flow across the intact tissue without altering aggregate frequency.
(7) In IDD patients the ultrafiltrates were active in the TTC assay and in the toad assay.
(8) About 2 weeks after metamorphosis, midwife toads Alytes obstetricans judge the size of a prey object mainly in scales of visual angle.
(9) However, we also demonstrate that published data show the existence of strong nonlinearities in the single-photon responses of toad and perhaps also of locust.
(10) A photoreactive analogue of vasotocin, [1-desamino,4-lysine(azidobenzoyl),8-arginine]vasotocin (4-N3-AVT), has been examined in the isolated toad urinary bladder for biological activity and binding to hormonal receptors.
(11) Earlier studies have shown that a substance(s) released from the egg jelly of the toad Bufo arenarum is required for fertilization.
(12) Commenters on his blog posted numerous fotozhaby – literally, photo-toads, or montages – in pastiche of the sham image.
(13) Schematic eyes, with homogeneous and non homogeneous lenses, were constructed for tadpoles, juvenile toads, and adult toads.
(14) Bidirectional sodium fluxes were measured across toad bladder sacs after eliminating active transport with ouabain.
(15) The properties of hyperpolarization-activated channels were studied in single smooth muscle cells from the stomach of the toad, Bufo marinus, using the patch-clamp technique.
(16) Findings from toad urinary bladder, Necturus gallbladder, and rabbit cortical collecting tubule are reviewed.
(17) The chronotropic and inotropic effects of stimulating the vagus on the hearts of the dog, duck and toad were studied.2.
(18) The inhibition of osmotic stimulated water flow in the isolated toad bladder by 0.1 mM sodium stibogluconate (pentavalent antimony) is described.
(19) Other than snake venoms, only venoms of the toad Bufo calamita and the lizards were hemorrhagic, and only venoms of the social wasps, social bees and harvester ant exhibited strong anticoagulant activity.
(20) By analogy with the comparable glands of the yellow-bellied toad and the grass frog, these are called the toxic, lumpy, mucous, callous, and small glands.