(1) The effects of hormonal promotion of T24-ras oncogene-transfected rat embryo fibroblasts (REF) were compared to cotransformation of these cells with adenovirus E1A and ras.
(2) Large gender differences were found in the correlations between the RAS, CR, run frequency, and run duration with the personality, mood, and locus of control scores.
(3) Here we co-inject RB protein with c-myc, EJ-ras, c-fos or c-jun protein.
(4) These results suggest that a certain minimum level of expression of c-myc is required for the maintenance of ras transformation in NIH 3T3 cells.
(5) This is the first clear example of activation of the K-ras gene by ethylating agents in a rodent lung tumor system.
(6) A total of 28 cell lines were selected for Geneticin - resistance and inoculated into the footpads of syngeneic animals following co-transfection with pSV2neo and genomic DNA, or transfection with plasmid constructs containing neo and the activated Ha-ras oncogene.
(7) In the second study, CFA, TiterMax, Adjuvax and RAS were compared in rabbits, mice and goats.
(8) One week after initiation is 1-2 months before the appearance of benign papillomas that harbor activated Ha-ras oncogenes when the initiated mice are promoted with the tumor promoter phorbol 12-myristate 13-acetate.
(9) The other three oncogenes namely c-K-ras, c-H-ras and c-myc, were not detected in these two carcinomas or the non-cancerous liver tissue adjacent to the carcinomas.
(10) Thus, a4 and a2 alleles of the c-Ha-ras-1 may perhaps be viewed as genetic markers of predisposition to lung, ovarian and thyroid cancer, respectively, in combination with other clinical parameters.
(11) Additionally, the amount of mRNAs for preproenkephalin as well as for the cellular proto-oncogenes c-myc, c-fos and c-H-ras, which are thought to be mediators of intracellular signal transduction, was determined in hippocampus in these same animals.
(12) The degree of staining for ras 11 was significantly related to the grade of differentiation and increased from Dukes stage A to C. Strong staining for ras 11 predicted a significantly shorter recurrence-free interval (p less than 0.001).
(13) The effects of oxidant stress were studied in immortalised hamster (BHK-21) and rat (208F) cell lines before and after transformation to the malignant state with polyoma virus, or activated H-ras, respectively.
(14) Upon stimulation with NGF, the percentage of Ras.GTP increased to 24% after 2 min, and the high level of Ras.GTP was maintained for at least 16 h. On the other hand, the activation of Ras by FGF and IL-6 showed distinct kinetics; about 3-fold increase of Ras.GTP was detected at 10 min, and afterward, the level returned to the basal level within 60 min.
(15) Transfection with normal and activated C-H-ras oncogenes only led to increases in the IC50s of alkylating agents.
(16) These cell lines also overexpress the Ha-ras proto-oncogene.
(17) In one patient with gastric carcinoma a c-Ha-ras-1 overexpression was detected due to its amplification both in tumour tissues and in regional metastasis.
(18) Our study gives further evidence that erb B, myc, Ha-ras and fos proto-oncogenes are involved in the control of cell growth and in the process of rat hepatocarcinogenesis.
(19) The Wap-ras gene was stably introduced into the mouse germ line of five transgenic mice (one male and four females).
(20) These results suggest that ras, fos, mos, src, and erbB-2 use a common cellular pathway for transforming cells.
Raw
Definition:
(superl.) Not altered from its natural state; not prepared by the action of heat; as, raw sienna; specifically, not cooked; not changed by heat to a state suitable for eating; not done; as, raw meat.
(superl.) Hence: Unprepared for use or enjoyment; immature; unripe; unseasoned; inexperienced; unpracticed; untried; as, raw soldiers; a raw recruit.
(superl.) Not worked in due form; in the natural state; untouched by art; unwrought.
(superl.) Not distilled; as, raw water
(superl.) Not spun or twisted; as, raw silk or cotton
(superl.) Not mixed or diluted; as, raw spirits
(superl.) Not tried; not melted and strained; as, raw tallow
(superl.) Not tanned; as, raw hides
(superl.) Not trimmed, covered, or folded under; as, the raw edge of a piece of metal or of cloth.
(superl.) Not covered; bare.
(superl.) Bald.
(superl.) Deprived of skin; galled; as, a raw sore.
(superl.) Sore, as if by being galled.
(superl.) Disagreeably damp or cold; chilly; bleak; as, a raw wind.
(n.) A raw, sore, or galled place; a sensitive spot; as, to touch one on the raw.
Example Sentences:
(1) Multiple stored energy levels were randomly tested and the percent successful defibrillation was plotted against the stored energy, and the raw data were fit by logistic regression.
(2) We previously established that the binding constant (Ka) of this receptor site for the chemically synthesized model AGE, 2-(2-furoyl)-4(5)-(2-furanyl)-1H- imidazole-butyric acid (FFI-BA), on cells of the mouse macrophagelike cell line RAW 264.7 is identical to that for AGE proteins.
(3) We studied the effect of a 2-hour exposure to 0.6 ppm of ozone on bronchial reactivity in 8 healthy, nonsmoking subjects by measuring the increase in airway resistance (Raw) produced by inhalation of histamine diphosphate aerosol (1.6 per cent, 10 breaths).
(4) It was also established that the Y. enterocolitica strains isolated from raw cow milk did not refer to the European serotypes 0:3 and 0:9 that were pathogenic for humans.
(5) On raw music scores a sex-linked, time-of-day-induced priming effect was due to the prior presentation of CVs--that is, cognitive priming.
(6) The norms are reported as "Scaled Score Equivalents of Raw Scores" for each age group and as "IQ Equivalents of Sums of Scaled Scores."
(7) Admirable, but will destroying ivory get that message through to poachers, ivory traffickers and the workshops in east Asia and elsewhere that buy smuggled raw ivory?
(8) Samples of raw cereals imported in Italy and of other foodstuffs that can be treated with bromine-containing fumigants were analysed for the total bromide content.
(9) Instead, they say, we should only eat plenty of lean meat and fish, with fruit and raw vegetables on the side.
(10) The report paints a picture characterised too often by international indifference, even over the collection and distribution of the raw data on migrant deaths.
(11) Raw Target RSM was force fed to 12 hens which were killed after varying time intervals (15 min., 30 min., 60 min.)
(12) Raw milk consumption, since it is not common, does not seem to have a major role in human infection.
(13) One hundred and thirty-two penial-preputial swabbings, 140 raw and 42 processed semen samples were cultured for mycoplasmas.
(14) The raw data are obtained by capillary gas chromatography using a nitrogen-phosphorus detector.
(15) We therefore surveyed patients with Parkinson's disease (PD) regarding early adult consumption of fruits and vegetables usually eaten raw, with seeds that are swallowed or scraped with the teeth.
(16) The raw air curve is determined by sequentially counting radionuclide activity in respiratory gases sampled at the mouth.
(17) The restriction enzyme patterns of the nine clinical isolates from the 1983 Massachusetts outbreak were identical to each other but differed from those of raw milk isolates recovered from sources supplying the pasteurizer.
(18) Nitrogen retention in lambs fed raw, dehulled lupins was equal (P greater than .10) to that of lambs fed SBM.
(19) It is postulated that rural children were being infected by campylobacters at an early age by drinking contaminated raw milk which was not normally available to city residents.
(20) The third step was the correction of raw FFR amplitudes by an algorithm that takes into account several noise values.