(1) The effects of hormonal promotion of T24-ras oncogene-transfected rat embryo fibroblasts (REF) were compared to cotransformation of these cells with adenovirus E1A and ras.
(2) Large gender differences were found in the correlations between the RAS, CR, run frequency, and run duration with the personality, mood, and locus of control scores.
(3) Here we co-inject RB protein with c-myc, EJ-ras, c-fos or c-jun protein.
(4) These results suggest that a certain minimum level of expression of c-myc is required for the maintenance of ras transformation in NIH 3T3 cells.
(5) This is the first clear example of activation of the K-ras gene by ethylating agents in a rodent lung tumor system.
(6) A total of 28 cell lines were selected for Geneticin - resistance and inoculated into the footpads of syngeneic animals following co-transfection with pSV2neo and genomic DNA, or transfection with plasmid constructs containing neo and the activated Ha-ras oncogene.
(7) In the second study, CFA, TiterMax, Adjuvax and RAS were compared in rabbits, mice and goats.
(8) One week after initiation is 1-2 months before the appearance of benign papillomas that harbor activated Ha-ras oncogenes when the initiated mice are promoted with the tumor promoter phorbol 12-myristate 13-acetate.
(9) The other three oncogenes namely c-K-ras, c-H-ras and c-myc, were not detected in these two carcinomas or the non-cancerous liver tissue adjacent to the carcinomas.
(10) Thus, a4 and a2 alleles of the c-Ha-ras-1 may perhaps be viewed as genetic markers of predisposition to lung, ovarian and thyroid cancer, respectively, in combination with other clinical parameters.
(11) Additionally, the amount of mRNAs for preproenkephalin as well as for the cellular proto-oncogenes c-myc, c-fos and c-H-ras, which are thought to be mediators of intracellular signal transduction, was determined in hippocampus in these same animals.
(12) The degree of staining for ras 11 was significantly related to the grade of differentiation and increased from Dukes stage A to C. Strong staining for ras 11 predicted a significantly shorter recurrence-free interval (p less than 0.001).
(13) The effects of oxidant stress were studied in immortalised hamster (BHK-21) and rat (208F) cell lines before and after transformation to the malignant state with polyoma virus, or activated H-ras, respectively.
(14) Upon stimulation with NGF, the percentage of Ras.GTP increased to 24% after 2 min, and the high level of Ras.GTP was maintained for at least 16 h. On the other hand, the activation of Ras by FGF and IL-6 showed distinct kinetics; about 3-fold increase of Ras.GTP was detected at 10 min, and afterward, the level returned to the basal level within 60 min.
(15) Transfection with normal and activated C-H-ras oncogenes only led to increases in the IC50s of alkylating agents.
(16) These cell lines also overexpress the Ha-ras proto-oncogene.
(17) In one patient with gastric carcinoma a c-Ha-ras-1 overexpression was detected due to its amplification both in tumour tissues and in regional metastasis.
(18) Our study gives further evidence that erb B, myc, Ha-ras and fos proto-oncogenes are involved in the control of cell growth and in the process of rat hepatocarcinogenesis.
(19) The Wap-ras gene was stably introduced into the mouse germ line of five transgenic mice (one male and four females).
(20) These results suggest that ras, fos, mos, src, and erbB-2 use a common cellular pathway for transforming cells.
Ray
Definition:
(v. t.) To array.
(v. t.) To mark, stain, or soil; to streak; to defile.
(n.) Array; order; arrangement; dress.
(n.) One of a number of lines or parts diverging from a common point or center, like the radii of a circle; as, a star of six rays.
(n.) A radiating part of a flower or plant; the marginal florets of a compound flower, as an aster or a sunflower; one of the pedicels of an umbel or other circular flower cluster; radius. See Radius.
(n.) One of the radiating spines, or cartilages, supporting the fins of fishes.
(n.) One of the spheromeres of a radiate, especially one of the arms of a starfish or an ophiuran.
(n.) A line of light or heat proceeding from a radiant or reflecting point; a single element of light or heat propagated continuously; as, a solar ray; a polarized ray.
(n.) One of the component elements of the total radiation from a body; any definite or limited portion of the spectrum; as, the red ray; the violet ray. See Illust. under Light.
(n.) Sight; perception; vision; -- from an old theory of vision, that sight was something which proceeded from the eye to the object seen.
(n.) One of a system of diverging lines passing through a point, and regarded as extending indefinitely in both directions. See Half-ray.
(n.) To mark with long lines; to streak.
(n.) To send forth or shoot out; to cause to shine out; as, to ray smiles.
(v. i.) To shine, as with rays.
(n.) Any one of numerous elasmobranch fishes of the order Raiae, including the skates, torpedoes, sawfishes, etc.
(n.) In a restricted sense, any of the broad, flat, narrow-tailed species, as the skates and sting rays. See Skate.
Example Sentences:
(1) The level of gadd45 mRNA increased rapidly after X rays at doses as low as 2 Gy.
(2) Pain is not reported in the removal area, the clinical examinations show identical findings on both patellar tendons, X-ray and ultrasound evaluations do not demonstrate any change in patellar position.
(3) Findings on plain X-ray of the abdomen, using the usual parameters of psoas and kidney shadows in the Nigerian, indicate that the two communities studied are similar but urinary calculi and urinary tract distortion are significantly more prominent in the community with the higher endemicity of urinary schistosomiasis.
(4) In the German Democratic Republic, patients with scleroderma and history of long term silica exposure are recognized as patients with occupational disease even though pneumoconiosis is not clearly demonstrated on X-ray film.
(5) A new type of Escherichia coli mutant which shows increased sensitivity to methyl methane sulfonate but not to UV light or to gamma rays was isolated after mutagenesis with N-methyl-N'-nitro-N-nitrosoguanidine.
(6) Thin films (OD approximately 0.7) of glucose-embedded membranes, prepared as a control, showed virtually 100% conversion to the M state, and stacks of such thin film specimens gave very similar x-ray diffraction patterns in the bR568 and the M412 state in most experiments.
(7) In 0.17 M Na+(aq), tRNA(Phe) exists in its native conformation and the number of strong binding sites (Ka greater than or equal to 10(4)) was estimated to be 3-4 by titration experiments, in agreement with X-ray structural data for crystalline tRNA(Phe) (Jack et al., 1977).
(8) Radiological findings on chest X-rays taken two weeks after BAI were evaluated according to Takeuchi's criteria.
(9) The intermandibularis is probably present only in electric rays.
(10) Carbopol-940 gels, being the best of those used, were studied further for the effect of its concentration and of additives (benzalkonium chloride, phenylmercuric nitrate, chlorbutol and disodium edetate), autoclaving at 121 degrees C for 30 min and irradiation with gamma rays (2.5 Mrad), on the end product.
(11) The X-ray tube rotates outside the detector array at the rate of one revolution per second.
(12) If this is what 70s stoners were laughing at, it feels like they’ve already become acquiescent, passive parts of media-relayed consumer society; precursors of the cathode-ray-frazzled pop-culture exegetists of Tarantino and Kevin Smith in the 90s.
(13) Chromosome aberrations were scored in BHK21 C13 Syrian hamster fibroblasts, exposed to 60Co gamma-rays, 250 kV X-rays, 15 MeV neutrons or neutrons of mean energy 2.1 MeV produced from the 9Be(d,n)10B reaction.
(14) The scatter measurement was made using a standard imaging geometry with both beam stops and an additional x-ray detector placed behind the standard imaging detector.
(15) Chest X-ray revealed multiple nodular lesions in both lung fields.
(16) The treatment group received 75 mg of roxatidine acetate hydrochloride at 9 PM and 12 to 13 hours later gastric juice secretion was measured with gastric x-ray films in both groups.
(17) All patients received an X-ray study of swallow at 3 months after the operation.
(18) Modifications in quaternary structure induced by variation of these physicochemical parameters were followed by means of X-ray and quasi-elastic light-scattering and quantified in terms of weight average molecular weight (M), radius of gyration (Rg) and hydrodynamic radius (Rh).
(19) Congenital defect of a cervical pedicle produces a rare clinical syndrome with a characteristic X-ray picture associated with vague clinical signs often accentuated after trauma.
(20) A chest X-ray examination showed a large mediastinal mass on the right.