(1) The effects of hormonal promotion of T24-ras oncogene-transfected rat embryo fibroblasts (REF) were compared to cotransformation of these cells with adenovirus E1A and ras.
(2) Large gender differences were found in the correlations between the RAS, CR, run frequency, and run duration with the personality, mood, and locus of control scores.
(3) Here we co-inject RB protein with c-myc, EJ-ras, c-fos or c-jun protein.
(4) These results suggest that a certain minimum level of expression of c-myc is required for the maintenance of ras transformation in NIH 3T3 cells.
(5) This is the first clear example of activation of the K-ras gene by ethylating agents in a rodent lung tumor system.
(6) A total of 28 cell lines were selected for Geneticin - resistance and inoculated into the footpads of syngeneic animals following co-transfection with pSV2neo and genomic DNA, or transfection with plasmid constructs containing neo and the activated Ha-ras oncogene.
(7) In the second study, CFA, TiterMax, Adjuvax and RAS were compared in rabbits, mice and goats.
(8) One week after initiation is 1-2 months before the appearance of benign papillomas that harbor activated Ha-ras oncogenes when the initiated mice are promoted with the tumor promoter phorbol 12-myristate 13-acetate.
(9) The other three oncogenes namely c-K-ras, c-H-ras and c-myc, were not detected in these two carcinomas or the non-cancerous liver tissue adjacent to the carcinomas.
(10) Thus, a4 and a2 alleles of the c-Ha-ras-1 may perhaps be viewed as genetic markers of predisposition to lung, ovarian and thyroid cancer, respectively, in combination with other clinical parameters.
(11) Additionally, the amount of mRNAs for preproenkephalin as well as for the cellular proto-oncogenes c-myc, c-fos and c-H-ras, which are thought to be mediators of intracellular signal transduction, was determined in hippocampus in these same animals.
(12) The degree of staining for ras 11 was significantly related to the grade of differentiation and increased from Dukes stage A to C. Strong staining for ras 11 predicted a significantly shorter recurrence-free interval (p less than 0.001).
(13) The effects of oxidant stress were studied in immortalised hamster (BHK-21) and rat (208F) cell lines before and after transformation to the malignant state with polyoma virus, or activated H-ras, respectively.
(14) Upon stimulation with NGF, the percentage of Ras.GTP increased to 24% after 2 min, and the high level of Ras.GTP was maintained for at least 16 h. On the other hand, the activation of Ras by FGF and IL-6 showed distinct kinetics; about 3-fold increase of Ras.GTP was detected at 10 min, and afterward, the level returned to the basal level within 60 min.
(15) Transfection with normal and activated C-H-ras oncogenes only led to increases in the IC50s of alkylating agents.
(16) These cell lines also overexpress the Ha-ras proto-oncogene.
(17) In one patient with gastric carcinoma a c-Ha-ras-1 overexpression was detected due to its amplification both in tumour tissues and in regional metastasis.
(18) Our study gives further evidence that erb B, myc, Ha-ras and fos proto-oncogenes are involved in the control of cell growth and in the process of rat hepatocarcinogenesis.
(19) The Wap-ras gene was stably introduced into the mouse germ line of five transgenic mice (one male and four females).
(20) These results suggest that ras, fos, mos, src, and erbB-2 use a common cellular pathway for transforming cells.
Sea
Definition:
(n.) One of the larger bodies of salt water, less than an ocean, found on the earth's surface; a body of salt water of second rank, generally forming part of, or connecting with, an ocean or a larger sea; as, the Mediterranean Sea; the Sea of Marmora; the North Sea; the Carribean Sea.
(n.) An inland body of water, esp. if large or if salt or brackish; as, the Caspian Sea; the Sea of Aral; sometimes, a small fresh-water lake; as, the Sea of Galilee.
(n.) The ocean; the whole body of the salt water which covers a large part of the globe.
(n.) The swell of the ocean or other body of water in a high wind; motion of the water's surface; also, a single wave; a billow; as, there was a high sea after the storm; the vessel shipped a sea.
(n.) A great brazen laver in the temple at Jerusalem; -- so called from its size.
(n.) Fig.: Anything resembling the sea in vastness; as, a sea of glory.
Example Sentences:
(1) A full-scale war is unlikely but there is clear concern in Seoul about the more realistic threat of a small-scale attack on the South Korean military or a group of islands near the countries' disputed maritime border in the Yellow Sea.
(2) Blood samples were collected from an antecubital vein at sea level (S1), in a base camp at 1515 m prior to the summit ascent (S2), on the summit at 3285 m after 6.5 hours of climbing (S3), at base camp immediately after the descent (S4), and at sea level following a trail descent from the base camp (S5).
(3) "In a sea of bubblegum-cute popsters, Sistar stand out for their cool and sexy image," says Scobie.
(4) The compromised ice sheet tilts and he sinks into the Arctic Sea on the back of his faltering white Icelandic pony.
(5) This is an edited extract from Across the Seas – Australia’s Response to Refugees: A History by Klaus Neumann, published by Black Inc. Books and on-sale now .
(6) Two years ago, the Intergovernmental Panel on Climate Change declared Egypt's Nile Delta to be among the top three areas on the planet most vulnerable to a rise in sea levels, and even the most optimistic predictions of global temperature increase will still displace millions of Egyptians from one of the most densely populated regions on earth.
(7) It is shown that the combined effects of altitude and wind assistance yielded an increment in the length of the jump of about 31 cm, compared to a corresponding jump at sea level under still air conditions.
(8) Two similar calici agents, San Miguel sea lion virus (SMSV) and vesicular exanthema of swine virus (VESV) are susceptible to the virucidal activity of disinfectants of differing formulation.
(9) The sea ice usually then begins to freeze again over the winter.
(10) The sequential resonance assignment of the 1H NMR spectrum of the antihypertensive and antiviral protein BDS-I from the sea anemone Anemonia sulcata is presented.
(11) In the present work by the method of molecular DNA hybridization there was shown a low degree of affinity of the standard museum strains of cholera vibrios to the respresentatives of the sea species V. parahaemolyticus and V. alginolyticus, and also halophilic vibrios identified earlier on the basis of phenotypical characteristics of the nucleotide DNA composition as Marinovibrio.
(12) A guide, £44pp, is compulsory ( rscn.org.jo ) 2 Discover the Nuweiba coast: Red Sea, Egypt Beach, Nuweiba, Sinai, Egypt.
(13) In Tokyo, the US president warned China against forcibly pressing its maritime claims, following Beijing's unilateral declaration last autumn of an air exclusion zone over Japanese-controlled islands in the East China Sea.
(14) The highest rates were observed where the inhabitants' activities were related to the sea.
(15) CyIIIa.CAT) expression simultaneously in embryos bearing excess competitor regulatory DNA, we developed, and here describe, a new procedure for generating transgenic sea urchin embryos in which all of the cells in many embryos, and most in others, bear the exogenous DNA.
(16) All have territorial disputes with Beijing over the South China Sea , a route for about $4.5tn (£3.4tn) in trade that the US is concerned China wants to fully control.
(17) This time, as a journalist covering the event, I was arrested on the high seas, briefly imprisoned and interrogated on Mururoa itself while the tests continued.
(18) The cytolytic activity of peritoneal SEA reactive effector cells was confined to the TCR alpha beta+ CD4- CD8+ CD45RC- cell population.
(19) A light rain pattered the rooftops of Los Mochis in Friday’s pre-dawn darkness, the town silent and still as the Sea of Cortez lapped its shore.
(20) With grievous amazement, never self-pitying but sometimes bordering on a sort of numbed wonderment, Levi records the day-to-day personal and social history of the camp, noting not only the fine gradations of his own descent, but the capacity of some prisoners to cut a deal and strike a bargain, while others, destined by their age or character for the gas ovens, follow "the slope down to the bottom, like streams that run down to the sea".