(1) The effects of hormonal promotion of T24-ras oncogene-transfected rat embryo fibroblasts (REF) were compared to cotransformation of these cells with adenovirus E1A and ras.
(2) Large gender differences were found in the correlations between the RAS, CR, run frequency, and run duration with the personality, mood, and locus of control scores.
(3) Here we co-inject RB protein with c-myc, EJ-ras, c-fos or c-jun protein.
(4) These results suggest that a certain minimum level of expression of c-myc is required for the maintenance of ras transformation in NIH 3T3 cells.
(5) This is the first clear example of activation of the K-ras gene by ethylating agents in a rodent lung tumor system.
(6) A total of 28 cell lines were selected for Geneticin - resistance and inoculated into the footpads of syngeneic animals following co-transfection with pSV2neo and genomic DNA, or transfection with plasmid constructs containing neo and the activated Ha-ras oncogene.
(7) In the second study, CFA, TiterMax, Adjuvax and RAS were compared in rabbits, mice and goats.
(8) One week after initiation is 1-2 months before the appearance of benign papillomas that harbor activated Ha-ras oncogenes when the initiated mice are promoted with the tumor promoter phorbol 12-myristate 13-acetate.
(9) The other three oncogenes namely c-K-ras, c-H-ras and c-myc, were not detected in these two carcinomas or the non-cancerous liver tissue adjacent to the carcinomas.
(10) Thus, a4 and a2 alleles of the c-Ha-ras-1 may perhaps be viewed as genetic markers of predisposition to lung, ovarian and thyroid cancer, respectively, in combination with other clinical parameters.
(11) Additionally, the amount of mRNAs for preproenkephalin as well as for the cellular proto-oncogenes c-myc, c-fos and c-H-ras, which are thought to be mediators of intracellular signal transduction, was determined in hippocampus in these same animals.
(12) The degree of staining for ras 11 was significantly related to the grade of differentiation and increased from Dukes stage A to C. Strong staining for ras 11 predicted a significantly shorter recurrence-free interval (p less than 0.001).
(13) The effects of oxidant stress were studied in immortalised hamster (BHK-21) and rat (208F) cell lines before and after transformation to the malignant state with polyoma virus, or activated H-ras, respectively.
(14) Upon stimulation with NGF, the percentage of Ras.GTP increased to 24% after 2 min, and the high level of Ras.GTP was maintained for at least 16 h. On the other hand, the activation of Ras by FGF and IL-6 showed distinct kinetics; about 3-fold increase of Ras.GTP was detected at 10 min, and afterward, the level returned to the basal level within 60 min.
(15) Transfection with normal and activated C-H-ras oncogenes only led to increases in the IC50s of alkylating agents.
(16) These cell lines also overexpress the Ha-ras proto-oncogene.
(17) In one patient with gastric carcinoma a c-Ha-ras-1 overexpression was detected due to its amplification both in tumour tissues and in regional metastasis.
(18) Our study gives further evidence that erb B, myc, Ha-ras and fos proto-oncogenes are involved in the control of cell growth and in the process of rat hepatocarcinogenesis.
(19) The Wap-ras gene was stably introduced into the mouse germ line of five transgenic mice (one male and four females).
(20) These results suggest that ras, fos, mos, src, and erbB-2 use a common cellular pathway for transforming cells.
Vas
Definition:
(n.) A vessel; a duct.
Example Sentences:
(1) A segment of vas deferens was transplanted to the contralateral deferens with the intention of improving treatment for certain cases of infertility caused by obstruction.
(2) To minimise the risk of recanalisation (0.2%), 20 mm of vas deferens was resected.
(3) At a concentration of 10 microM, tetraamine 4 did not affect histamine and 5-hydroxytryptamine receptors of guinea pig ileum or alpha-adrenoreceptors of guinea pig atria whereas it inhibited postsynaptic alpha-adrenoreceptors of rat vas deferens with a -log K value of 5.23 and nicotinic receptors of frog rectus abdominis with an IC50 value of 0.23 microM.
(4) Emphasis is placed on techniques that prevent spontaneous recanalization of the ends of the vas deferens after vasectomy.
(5) After properly fixing the vas deferens with a ring clamp, the surgeon pierces the scrotal skin, vas sheath, and vas deferens in the midline with a curved dissecting clamp held at a 45 degree angle from horizontal.
(6) The acrosin inhibitors are localized in the mucosa cells of the cauda epididymis, the vas deferens, the seminal vesicles, the urethra and distinct glandular units of the prostate.
(7) It is thus concluded that the active core for the morphine like activity in the mouse vas deferens bioassay is the fragment 61-65 of beta-LPH.
(8) Microsurgical vasovasostomy for the reversal of elective bilateral segmental vasectomy (vasectomy, vas ligation) was done in 57 patients (61 operations) between May 1977 and March 1984.
(9) There was a significant positive correlation between the efflux of noradrenaline from platelets and vas deferens (r = 0.56, P less than 0.001).
(10) Supersensitivity to noradrenaline was produced by both of the stereoisomers in isolated vas deferens of guinea-pigs although there was no difference in the activity.
(11) At lesser intensities, VAS occasionally produced a small pressor response.
(12) Probably there is a continuity of this system throughout the entire vascular pole including (1) all granulated cells, (2) all lacis cells, (3) the mesangium cells and (4) the adjacent smooth muscle cells of the vas afferens and vas efferens.
(13) Pain scores (VAS) and responses to a pain questionnaire were similar for both groups; however, within Group B improvement in mean VAS scores at rest with time were more sustained.
(14) Various techniques have been described, but in this surgeon's opinion the simplest and best method is to remove a length of a vas such that it becomes a physical impossibility to approximate the cut ends.
(15) A 10-month-old boy with a crossed ectopic testis and a common vas deferens is presented.
(16) Within the epididymis, regions closest to the testis develop soluble ACE activity about 1 week before those nearest to the vas deferens.
(17) Pretreatment of the vas deferens with both HNBTG and 2'-deoxycoformycin eliminated the difference in inhibitory potency between adenosine and 2-chloroadenosine.
(18) We interpret these results to indicate that angiotensins stimulate PGE production by adrenergic nerves in the vas deferens and that released norepinephrine mediates a part of the PGE production in response to the angiotensins.
(19) The effects of the ATP affinity label periodate-oxidized ATP (ATP-2',3'-dialdehyde; P-ATP) on contractile responses of the guinea pig vas deferens to ATP was characterized and compared to the effects of the specific P2x-purinoceptor photoaffinity label antagonist, arylazido aminopropionyl ATP (ANAPP3).
(20) Knowledge of the mechanical properties of the vas deferens is important in order to understand the mechanical interaction between an intravasal device (IVD) and the vas deferens--a necessary step for successful long-term implantation.