What's the difference between refine and subtilize?
Refine
Definition:
(v. t.) To reduce to a fine, unmixed, or pure state; to free from impurities; to free from dross or alloy; to separate from extraneous matter; to purify; to defecate; as, to refine gold or silver; to refine iron; to refine wine or sugar.
(v. t.) To purify from what is gross, coarse, vulgar, inelegant, low, and the like; to make elegant or exellent; to polish; as, to refine the manners, the language, the style, the taste, the intellect, or the moral feelings.
(v. i.) To become pure; to be cleared of feculent matter.
(v. i.) To improve in accuracy, delicacy, or excellence.
(v. i.) To affect nicety or subtilty in thought or language.
Example Sentences:
(1) The patients had a high AP, consumed more alcohol, were more well-fed, older and consumed more refined carbohydrates per 1 kg bw and less cholesterol and vegetable protein.
(2) After restrained least-squares refinement of the enzyme-substrate complex with the riboflavin omitted from the model, additional electron density appeared near the pyrophosphate, which indicated the presence of an ADPR molecule in the FAD binding site of PHBH.
(3) Well-refined x-ray structures of the liganded forms of the wild-type and a mutant protein isolated from a strain defective in chemotaxis but fully competent in transport have provided a molecular view of the sugar-binding site and of a site for interacting with the Trg transmembrane signal transducer.
(4) To meet these prerequisites we have introduced some technical refinements: (1) computer-controlled rectilinear translations of the target in combination with different angular positions of the source and (2) computer-controlled rotations of the target around a vertical axis in combination with different angular positions of the source.
(5) Percutaneous transhepatic biliary drainage (PTBD) was conceptualized more than 35 years ago, but its clinical application only flourished in the past 10 years after a number of technical refinements.
(6) In 1984 the press-fit condylar knee was first introduced and was intended to provide a condylar knee system primarily for posterior cruciate retention that addressed refinements in metallurgy, prosthetic geometry and sizing, cementless fixation, inventory management, and instrumentation.
(7) Obviously, the sheer number of lasers being used both clinically and experimentally indicates a great potential for further advancement and refinement in technique and surgical outcomes.
(8) Phases from x-ray structure factors (R = 0.43) computed from this model were then used in the calculation of another electron density map against which the model was further refined.
(9) Staging classifications are being refined to reflect increasing knowledge of important prognostic indicators, e.g., absence or presence of lymph node involvement, pattern of lymph node involvement, and absence or presence of visceral disease.
(10) The ordered aspect of the genetic code table makes this result a plausible starting point for studies of the origin and evolution of the genetic code: these could include, besides a more refined optimization principle at the logical level, some effects more directly related to the physico-chemical context, and the construction of realistic models incorporating both aspects.
(11) The structure of Mn(III) superoxide dismutase (Mn(III)SOD) from Thermus thermophilus, a tetramer of chains 203 residues in length, has been refined by restrained least-squares methods.
(12) Based on the refined atomic coordinates of the tRNAphe in the orthorhombic crystal, on the recent advances in the distance dependence of the ring-current magnetic field effects and on the adopted values for the isolated hydrogen-bonded NH resonances, a computed spectrum consisting of 23 protons was constructed.
(13) It can be used as a simple screening procedure to help determine which of many possible anthelmintic control strategies should be selected for more detailed examination in the field, and it provides a theoretical framework within which ideas concerning the epidemiology of parasitic gastroenteritis can be assessed and refined.
(14) The advances in lid and orbital surgery are due to the improvements made in diagnostic equipment and to technical refinements.
(15) The group’s refining business performed better than expected, more than doubling profit to $2.2bn from $1bn.
(16) They also suggest that both the migration of cortical neurons on glia and the refinement of the mapping between the peripheral whisker field and its cortical representation may depend upon the distribution of substrate adhesion molecules.
(17) Thus the present study gives support for a protective effect associated with a fiber-rich or vegetable-rich diet, while it indicates that frequent consumption of refined starchy foods, eggs and fat-rich foods such as cheese and red meat is a risk factor for colo-rectal cancer.
(18) Synthesis and discussion is focused on five major areas in which gerontological continuity and change are evidenced: 1) transformation of basic themes over time; 2) gerontology's identity crisis; 3) the social ideology of gerontology; 4) evolution and refinement of gerontological ideas and methods; and 5) temporal frameworks.
(19) The course content and format were refined after 11 pharmacists completed a pilot program.
(20) This has led to important advances in our understanding of the mechanism of axonal guidance, the physiology of neurotrophic factors and the establishment and refinement of neural connections.
Subtilize
Definition:
(v. t.) To make thin or fine; to make less gross or coarse.
(v. t.) To refine; to spin into niceties; as, to subtilize arguments.
(v. i.) To refine in argument; to make very nice distinctions.
Example Sentences:
(1) After operative methods have been subtilized and radicalized only preventive medical examinations and early public instruction may improve the prognosis of the patients concerned.
(2) Accurate preoperative evaluation and subtile operative technique are imperative, however.
(3) More subtile effects of milk processing on milk digestibility and stomach emptying are mentioned.
(4) It was possible histologically to follow the most subtile alterations on the membranes from the very beginning of the chronic bronchitis.
(5) The present paper suggests the autometallographic demonstration of intralysosomal silver as a sensitive tool for the detection of subtile toxic effects in cell cultures, the method is suggested to primarily detect lysosomal damage.
(6) Fatty acids damage the membrane integrity in such a way that the subtile equilibrium between the factors is disturbed.
(7) The removal of the angioma requires the most subtile preparation.
(8) A microscopical examination of the Leptothrix-filaments revealed a subtile segmentation and sporulation.
(9) In the individual case, it is necessary to identify the major causes by employing subtile investigative measures, in order to be able to plan rational treatment.
(10) Inhibited subtilisin (Subtilism Carlsberg; Subtilopeptidase A) is unfolded in the presence of 7 M guanidine hydrochloride.
(11) There was concluded firstly that the possibility of metastases in the pelvic lymph nodes is dependent from the size of the primary tumor and secondly that before treatment a subtile diagnostic procedure secures that only good cases of cervical cancer FIGO stage I b are operated on by radical vaginal hysterectomy (Schauta-Amreich).
(12) The stereological investigations revealed a subtile reaction of the medial stapled tibial plate in a total of 37 domestic pigs (10 weeks old) during the postoperative follow-up (up to 17 weeks).
(13) Despite subtile changes of glucose, glucagon and to a lesser degree insulin levels which would be suggestive of insulin resistance, the data obtained from skeletal muscle argue against peripheral insulin resistance in spontaneously hypertensive rats.
(14) For the clarification of pathogenesis and clinical relevance of decreases of the triiodothyronine (T3) level in patients with chronic inflammatory rheumatism in a group of 63 patients with clinically, paraclinically and roentgenologically diagnosed rheumatoid arthritis (59 times) and with SLE (4 times), respectively, parallel were determined parameters of the thyroid gland function and of the rheumatic activity as well as a subtile drug anamnesis for the medication of antirheumatic drugs was established.
(15) -- It has been refered to the importance of the exact conisation technique and subtile histotechnical obtaining of slides in step sections.
(16) A stable implantation of this biocompatible material is possible, if the primary attachment by means of special construction features and subtile operation technique is ensured.
(17) The measurement procedure was found to be very sensitive with respect to all fractions in evaluating the subtile differences between different lot numbers of the aerosol.
(18) The other highly vascular neoplasms show unspecific signs of vascular malignant tumors; subtile angiographic signs may, however, be present and help in the differential diagnosis.
(19) Subtile investigations in protein diagnostics are required for avoiding incomplete monoclonal immunoglobulins which may greatly enter the kidneys to be overlooked.
(20) When photographs taken at diastolic and systolic culminations were compared, with the haploscope, when stereoscopically seen, they clearly showed the subtile deformation of the vessels under a stereoscopic effect.